scholarly journals Asymmetric Hybrid Polymer-Lipid Giant Vesicles as Cell Membrane Mimics

2017 ◽  
Vol 5 (1) ◽  
pp. 1700453 ◽  
Author(s):  
Ariane Peyret ◽  
Emmanuel Ibarboure ◽  
Jean-François Le Meins ◽  
Sebastien Lecommandoux
Keyword(s):  
Cell Membrane ◽  
Hybrid Polymer ◽  
Giant Vesicles ◽  
Membrane Mimics ◽  
Asymmetric Hybrid

Unraveling Dendrimer Translocation Across Cell Membrane Mimics

Langmuir ◽  
2012 ◽  
Vol 28 (36) ◽  
pp. 13025-13033 ◽  
Author(s):  
Anna Åkesson ◽  
Tania K. Lind ◽  
Robert Barker ◽  
Arwel Hughes ◽  
Marité Cárdenas
Keyword(s):  
Cell Membrane ◽  
Membrane Mimics

scholarly journals HIV Fusion Peptide Penetrates, Disorders, and Softens T-Cell Membrane Mimics

2010 ◽  
Vol 402 (1) ◽  
pp. 139-153 ◽  
Author(s):  
Stephanie Tristram-Nagle ◽  
Rob Chan ◽  
Edgar Kooijman ◽  
Pradeep Uppamoochikkal ◽  
Wei Qiang ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Membrane ◽  
Fusion Peptide ◽  
Membrane Mimics ◽  
T Cell Membrane

scholarly journals HIV Fusion Peptide Penetrates, Disorders and Softens T-Cell Membrane Mimics

2011 ◽  
Vol 100 (3) ◽  
pp. 186a
Author(s):  
Stephanie Tristram-Nagle ◽  
Rob Chan ◽  
Edgar E. Kooijman ◽  
Wei Qiang ◽  
David P. Weliky ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Membrane ◽  
Fusion Peptide ◽  
Membrane Mimics ◽  
T Cell Membrane

scholarly journals Toward Realistic Large-Area Cell Membrane Mimics: Excluding Oil, Controlling Composition, and Including Ion Channels

Langmuir ◽  
2018 ◽  
Vol 34 (20) ◽  
pp. 5880-5888 ◽  
Author(s):  
Peter J. Beltramo ◽  
Laura Scheidegger ◽  
Jan Vermant
Keyword(s):  
Ion Channels ◽  
Cell Membrane ◽  
Large Area ◽  
Membrane Mimics

scholarly journals Deformation but not migration and rotation – a model study on vesicle biomechanics in a uniform DC electric field

2016 ◽  
Vol 3 (1) ◽  
pp. 18
Author(s):  
Hui Ye ◽  
Austen Curcuru
Keyword(s):  
Cell Membrane ◽  
Electric Field ◽  
Electric Fields ◽  
Radial Pressure ◽  
Biological Properties ◽  
Phospholipid Bilayer ◽  
Biological Cell ◽  
Biological Cells ◽  
Giant Vesicles ◽  
Dc Electric Field

Background: Biological cells migrate, deform and rotate in various types of electric fields, which have significant impact on the normal cellular physiology. To investigate electrically-induced deformation, researchers have used artificial giant vesicles that mimic the phospholipid bilayer cell membrane. Containing primarily the neutral molecule phosphatidylcholine, these vesicles deformed under evenly distributed, strong direct current (DC) electric fields. Interestingly, they did not migrate or rotate. A biophysical mechanism underlying the kinematic differences between the biological cells and the vesicles under electric stimulation has not been worked out. Methods: We modeled the vesicle as a leaky, dielectric sphere and computed the surface pressure, rotation torques and translation forces applied on the vesicle by a DC electric field. We compared these measurements with those in a biological cell that contains non-zero, intrinsic charges (carried by the functional groups on the membrane). Results: For both the vesicle and the cell, the electrically-induced charges interacted with the local electric field to generate radial pressure for deformation. However, due to the symmetrical distribution of both the charges and the electric field on the vesicle/cell surface, the electric field could not generate net translation force or rotational torques. For a biological cell, the intrinsic charges carried by the cell membrane could account for its migration and rotation in a DC electric field. Conclusions: Results from this work suggests an interesting control diagram of cellular kinematics and movements by the electric field: cell deformation and migration can be manipulated by directly targeting different charged groups on the membrane. Fate of the cell in an electric field depends not only on the delicately controlled field parameters, but also on the biological properties of the cell.

scholarly journals Toward Realistic Cell Membrane Mimics

2019 ◽  
Vol 116 (3) ◽  
pp. 80a
Author(s):  
Peter Beltramo
Keyword(s):  
Cell Membrane ◽  
Membrane Mimics
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