Highly Efficient Asymmetric Three-Component Vinylogous Mannich Reaction Catalyzed by a Chiral Scandium(III)- N,N′-Dioxide Complex

2010 ◽  
Vol 352 (6) ◽  
pp. 976-980 ◽  
Author(s):  
Qi Zhang ◽  
Yonghai Hui ◽  
Xin Zhou ◽  
Lili Lin ◽  
Xiaohua Liu ◽  
...  
2017 ◽  
Vol 15 (43) ◽  
pp. 9217-9225 ◽  
Author(s):  
Saumen Hajra ◽  
Suhas Shivajirao Bhosale ◽  
Atanu Hazra

A highly efficient TMSOTf-mediated asymmetric acetate-Mannich reaction of chiral isatin derived ketimines and S-phenyl thioacetate was developed to afford the direct synthesis of indole-based β3,3-amino acid thioester with excellent selectivity (dr > 98 : 2). Syntheses of (+)-AG-041R and 3-aminopyrroloindoline have been accomplished utilizing the method.


ChemInform ◽  
2010 ◽  
Vol 32 (37) ◽  
pp. no-no
Author(s):  
Changtao Qian ◽  
Feifeng Gao ◽  
Ruifang Chen

2019 ◽  
Vol 33 (7) ◽  
Author(s):  
Yunyun Wang ◽  
Yajun Jian ◽  
Ya Wu ◽  
Huaming Sun ◽  
Guofang Zhang ◽  
...  

ChemInform ◽  
2006 ◽  
Vol 37 (37) ◽  
Author(s):  
Najmodin Azizi ◽  
Lalleh Torkiyan ◽  
Mohammad R. Saidi

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