Asymmetric Phase-Transfer Catalysts Bearing Multiple Hydrogen-Bonding Donors: Highly Efficient Catalysts for Enantio- and Diastereoselective Nitro-Mannich Reaction of Amidosulfones

2014 ◽  
Vol 16 (24) ◽  
pp. 6432-6435 ◽  
Author(s):  
Bin Wang ◽  
Yuxin Liu ◽  
Cong Sun ◽  
Zhonglin Wei ◽  
Jungang Cao ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Mannich Reaction ◽  
Phase Transfer ◽  
Phase Transfer Catalysts ◽  
Highly Efficient ◽  
Multiple Hydrogen Bonding

Organocatalyzed Heterocyclic Transformations In Green Media: A Review

2020 ◽  
Vol 07 ◽  
Author(s):  
Neslihan Demirbas ◽  
Ahmet Demirbas
Keyword(s):  
Hydrogen Bonding ◽  
Phase Transfer ◽  
Noncovalent Interactions ◽  
Binding Capacity ◽  
Chemical Transformations ◽  
Organic Transformations ◽  
Phase Transfer Catalysts ◽  
Waste Production ◽  
Synthetic Methodologies ◽  
Organocatalytic Reactions

Background: Since the discovery of metal-free catalysts or organocatalysts about twenty years ago, a number of small molecules with different structures have been using to accelerate organic transformations. With the development of environmental awareness, in order to obtain highly privileged scaffolds, scientists have directed their studies towards the synthetic methodologies which minimize or preferably eliminate the formation of waste, avoid from toxic solvents and reagents and use renewable starting materials as far as possible. Methods: In this connection, the organocatalytic reactions providing efficiency and selectivity for most of case have become an endless topic in organic chemistry since several advantages from both practical and environmental standpoints. Organocatalysts supplying transformation of reactants into products with the least possible waste production have been serving to the concept of green chemistry. Results and Conclusion: Organocatalysts have been classified on the basis of their binding capacity to the substrate with covalently or noncovalent interactions involving hydrogen bonding and electrostatic interaction. Diverse types of small organic compounds including proline and its derivatives, phase-transfer catalysts, (thio)urease, phosphoric acids, sulfones, N-oxides, guanidines, cinchona derivatives, aminoindanol and amino acids have been utilized as hydrogen bonding organocatalysts in different chemical transformations.

Highly efficient polymer supported phase-transfer catalysts containing hydrogen bond inducing functional groups

2008 ◽  
Vol 49 (8) ◽  
pp. 1380-1383 ◽  
Author(s):  
Qinghua Shi ◽  
Yeon-Ju Lee ◽  
Mi-Jeong Kim ◽  
Mi-Kyung Park ◽  
Kyoungyim Lee ◽  
...  
Keyword(s):  
Hydrogen Bond ◽  
Functional Groups ◽  
Phase Transfer ◽  
Phase Transfer Catalysts ◽  
Highly Efficient ◽  
Polymer Supported

Diastereo- and enantioselective nitro-Mannich reaction of isatin-derived N-Boc ketimines catalyzed by chiral phase-transfer catalysts

2018 ◽  
Vol 42 (3) ◽  
pp. 1608-1611 ◽  
Author(s):  
Yuxin Liu ◽  
Jingdong Wang ◽  
Zhonglin Wei ◽  
Jungang Cao ◽  
Dapeng Liang ◽  
...  
Keyword(s):  
Mannich Reaction ◽  
Phase Transfer ◽  
Cinchona Alkaloid ◽  
Chiral Phase ◽  
Phase Transfer Catalysts ◽  
Chiral Phase Transfer Catalysts

A series of 3-substituted 3-amino-oxindoles were constructed in excellent yields (96–99%) with high enantioselectivities (up to 95% ee) and diastereoselectivities (up to 95 : 5 dr) catalyzed by Cinchona alkaloid-derived phase-transfer catalysts.

ChemInform Abstract: A New Family of Cinchona-Derived Bifunctional Asymmetric Phase-Transfer Catalysts: Application to the Enantio- and Diastereoselective Nitro-Mannich Reaction of Amidosulfones.

ChemInform ◽  
2012 ◽  
Vol 43 (38) ◽  
pp. no-no
Author(s):  
Kayli M. Johnson ◽  
Matt S. Rattley ◽  
Filippo Sladojevich ◽  
David M. Barber ◽  
Marta G. Nunez ◽  
...  
Keyword(s):  
Mannich Reaction ◽  
Phase Transfer ◽  
Phase Transfer Catalysts ◽  
New Family

A New Family of Cinchona-Derived Bifunctional Asymmetric Phase-Transfer Catalysts: Application to the Enantio- and Diastereoselective Nitro-Mannich Reaction of Amidosulfones

2012 ◽  
Vol 14 (10) ◽  
pp. 2492-2495 ◽  
Author(s):  
Kayli M. Johnson ◽  
Matt S. Rattley ◽  
Filippo Sladojevich ◽  
David M. Barber ◽  
Marta G. Nuñez ◽  
...  
Keyword(s):  
Mannich Reaction ◽  
Phase Transfer ◽  
Phase Transfer Catalysts ◽  
New Family
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