scholarly journals Curvature Elasticity‐Driven Leaflet Asymmetry and Interleaflet Raft Coupling in Supported Membranes

2018 ◽  
Vol 5 (23) ◽  
pp. 1801290 ◽  
Author(s):  
Yong‐Sang Ryu ◽  
Luke R. Jordan ◽  
Nathan J. Wittenberg ◽  
Sang Moon Kim ◽  
Daehan Yoo ◽  
...  
Keyword(s):  
Supported Membranes ◽  
Curvature Elasticity

scholarly journals Lipid Membranes: Curvature Elasticity‐Driven Leaflet Asymmetry and Interleaflet Raft Coupling in Supported Membranes (Adv. Mater. Interfaces 23/2018)

2018 ◽  
Vol 5 (23) ◽  
pp. 1870117
Author(s):  
Yong‐Sang Ryu ◽  
Luke R. Jordan ◽  
Nathan J. Wittenberg ◽  
Sang Moon Kim ◽  
Daehan Yoo ◽  
...  
Keyword(s):  
Lipid Membranes ◽  
Supported Membranes ◽  
Curvature Elasticity

scholarly journals Membrane fusion studied by colloidal probes

2021 ◽  
Vol 50 (2) ◽  
pp. 223-237 ◽  
Author(s):  
Hannes Witt ◽  
Filip Savić ◽  
Sarah Verbeek ◽  
Jörn Dietz ◽  
Gesa Tarantola ◽  
...  
Keyword(s):  
Membrane Fusion ◽  
Optical Tweezers ◽  
Three Dimensional ◽  
Biological Processes ◽  
Supported Membranes ◽  
Supported Bilayers ◽  
Force Microscopy ◽  
Advantages And Disadvantages ◽  
Atomic Force ◽  
Colloidal Probes

AbstractMembrane-coated colloidal probes combine the benefits of solid-supported membranes with a more complex three-dimensional geometry. This combination makes them a powerful model system that enables the visualization of dynamic biological processes with high throughput and minimal reliance on fluorescent labels. Here, we want to review recent applications of colloidal probes for the study of membrane fusion. After discussing the advantages and disadvantages of some classical vesicle-based fusion assays, we introduce an assay using optical detection of fusion between membrane-coated glass microspheres in a quasi two-dimensional assembly. Then, we discuss free energy considerations of membrane fusion between supported bilayers, and show how colloidal probes can be combined with atomic force microscopy or optical tweezers to access the fusion process with even greater detail.

Mechanics of membrane–membrane adhesion

2011 ◽  
Vol 16 (8) ◽  
pp. 872-886 ◽  
Author(s):  
Ashutosh Agrawal
Keyword(s):  
Lipid Vesicles ◽  
Spontaneous Curvature ◽  
Interface Conditions ◽  
Point Boundary ◽  
Lagrange Equations ◽  
Equilibrium Conditions ◽  
Numerical Studies ◽  
Curvature Elasticity ◽  
Equilibrium Shapes ◽  
Membrane Adhesion

Curvature elasticity is used to derive the equilibrium conditions that govern the mechanics of membrane–membrane adhesion. These include the Euler–Lagrange equations and the interface conditions which are derived here for the most general class of strain energies permissible for fluid surfaces. The theory is specialized for homogeneous membranes with quadratic ‘Helfrich’-type energies with non-uniform spontaneous curvatures. The results are employed to solve four-point boundary value problems that simulate the equilibrium shapes of lipid vesicles that adhere to each other. Numerical studies are conducted to investigate the effect of relative sizes, osmotic pressures, and adhesion-induced spontaneous curvature on the morphology of adhered vesicles.

Phosphorylation of C-terminal polycystin-2 influences the interaction with PIGEA14: A QCM study based on solid supported membranes

2013 ◽  
Vol 437 (4) ◽  
pp. 532-537 ◽  
Author(s):  
Daniela Morick ◽  
Michaela Schatz ◽  
Raphael Hubrich ◽  
Helen Hoffmeister ◽  
Anya Krefft ◽  
...  
Keyword(s):  
Supported Membranes ◽  
Solid Supported Membranes

Blocked Lipid Exchange in Bilayers and its Possible Influence on the Shape of Vesicles

1974 ◽  
Vol 29 (9-10) ◽  
pp. 510-515 ◽  
Author(s):  
W Helfrich
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Spontaneous Curvature ◽  
Lipid Exchange ◽  
Lipid Distribution ◽  
Shape Transformations ◽  
Curvature Elasticity ◽  
Possible Cause

Abstract The role of lipid exchange in the curvature elasticity of bilayers is studied theoretically. Blocking of exchange between the monolayers may give rise to a nonequilibrium lipid distribution going hand in hand with a spontaneous curvature. Some possible consequences for vesicular deformations are discussed. Lipid nonequilibrium is tentatively suggest as one possible cause for certain shape transformations of red blood cells

Sign in / Sign up

Export Citation Format

Share Document