CO2-Induced Tunable and Reversible Surface Wettability of Honeycomb Structured Porous Films for Cell Adhesion

2016 ◽  
Vol 3 (7) ◽  
pp. 1500623 ◽  
Author(s):  
Hongyao Yin ◽  
Anne-Laure Bulteau ◽  
Yujun Feng ◽  
Laurent Billon
Keyword(s):  
Cell Adhesion ◽  
Surface Wettability ◽  
Porous Films

scholarly journals Surface wettability of plasma SiO x :H nanocoating-induced endothelial cells' migration and the associated FAK-Rho GTPases signalling pathways

2011 ◽  
Vol 9 (67) ◽  
pp. 313-327 ◽  
Author(s):  
Yang Shen ◽  
Guixue Wang ◽  
Xianliang Huang ◽  
Qin Zhang ◽  
Jiang Wu ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Rho Gtpases ◽  
Vascular Endothelial Cell ◽  
Contact Angles ◽  
Surface Wettability ◽  
Signalling Pathways ◽  
Hydrophobic Surfaces ◽  
Water Contact ◽  
Hydrophilic Surfaces ◽  
And Migration

Vascular endothelial cell (EC) adhesion and migration are essential processes in re-endothelialization of implanted biomaterials. There is no clear relationship and mechanism between EC adhesion and migration behaviour on surfaces with varying wettabilities. As model substrates, plasma SiO x :H nanocoatings with well-controlled surface wettability (with water contact angles in the range of 98.5 ± 2.3° to 26.3 ± 4.0°) were used in this study to investigate the effects of surface wettability on cell adhesion/migration and associated protein expressions in FAK-Rho GTPases signalling pathways. It was found that EC adhesion/migration showed opposite behaviour on the hydrophilic and hydrophobic surfaces (i.e. hydrophobic surfaces promoted EC migration but were anti-adhesions). The number of adherent ECs showed a maximum on hydrophilic surfaces, while cells adhered to hydrophobic surfaces exhibited a tendency for cell migration. The focal adhesion kinase (FAK) inhibitor targeting the Y-397 site of FAK could significantly inhibit cell adhesion/migration, suggesting that EC adhesion and migration on surfaces with different wettabilities involve ( p )FAK and its downstream signalling pathways. Western blot results suggested that the FAK-Rho GTPases signalling pathways were correlative to EC migration on hydrophobic plasma SiO x :H surfaces, but uncertain to hydrophilic surfaces. This work demonstrated that surface wettability could induce cellular behaviours that were associated with different cellular signalling events.

scholarly journals Preparation of a Cage-Type Polyglycolic Acid/Collagen Nanofiber Blend with Improved Surface Wettability and Handling Properties for Potential Biomedical Applications

Polymers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 3458
Author(s):  
Sofia El-Ghazali ◽  
Hisatoshi Kobayashi ◽  
Muzamil Khatri ◽  
Duy-Nam Phan ◽  
Zeeshan Khatri ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Biomedical Applications ◽  
Structural Integrity ◽  
Polyglycolic Acid ◽  
Electrospinning Process ◽  
Surface Wettability ◽  
Practical Utilization ◽  
Electrospinning Method ◽  
Nitrogen Treatment ◽  
Surgical Operations

Electrospun biobased polymeric nanofiber blends are widely used as biomaterials for different applications, such as tissue engineering and cell adhesion; however, their surface wettability and handling require further improvements for their practical utilization in the assistance of surgical operations. Therefore, Polyglycolic acid (PGA) and collagen-based nanofibers with three different ratios (40:60, 50:50 and 60:40) were prepared using the electrospinning method, and their surface wettability was improved using ozonation and plasma (nitrogen) treatment. The effect on the wettability and the morphology of pristine and blended PGA and collagen nanofibers was assessed using the WCA test and SEM, respectively. It was observed that PGA/collagen with the ratio 60:40 was the optimal blend, which resulted in nanofibers with easy handling and bead-free morphology that could maintain their structural integrity even after the surface treatments, imparting hydrophilicity on the surface, which can be advantageous for cell adhesion applications. Additionally, a cage-type collector was used during the electrospinning process to provide better handling properties to (PGA/collagen 60:40) blend. The resultant nanofiber mat was then incorporated with activated poly (α,β-malic acid) to improve its surface hydrophilicity. The chemical composition of PGA/collagen 60:40 was assessed using FTIR spectroscopy, supported by Raman spectroscopy.

Surface Wettability Switched Cell Adhesion and Detachment on Conducting Polymer Nanoarray

2016 ◽  
Vol 3 (19) ◽  
pp. 1600598 ◽  
Author(s):  
Yingying Li ◽  
Yan Wei ◽  
Jingwen Liao ◽  
Yuwei Hao ◽  
Chengyun Ning ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Conducting Polymer ◽  
Surface Wettability

scholarly journals Surface wettability and strong adhesion of medical polyurethane elastomer porous films by microphase separation

AIP Advances ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 075309 ◽  
Author(s):  
Mingshan Xue ◽  
Yuwei Ji ◽  
Junfei Ou ◽  
Fajun Wang ◽  
Changquan Li ◽  
...  
Keyword(s):  
Microphase Separation ◽  
Surface Wettability ◽  
Polyurethane Elastomer ◽  
Porous Films ◽  
Strong Adhesion

Enhanced Multiple Surface Properties of Biometallic Materials by Laser Microprocessing

2021 ◽  
Author(s):  
Bing Wang ◽  
Jiaru Zhang ◽  
Yingchun Guan
Keyword(s):  
Cell Adhesion ◽  
Surface Wettability ◽  
Good Mechanical Property ◽  
Metallic Materials ◽  
Water Contact ◽  
Nano Structure ◽  
Practical Applications ◽  
E Coli ◽  
Corrosion Resistance Property ◽  
High Flexibility

Abstract Metallic materials have been widely used owing to their good mechanical property and high flexibility. However, there are certain limitations for practical applications such as low anti-bacterial, cell adhesion, surface wettability and corrosion resistance property. In this paper, laser microprocessing of titanium (Ti) alloy and magnesium (Mg) alloy has been conducted, respectively. The cell adhesion of Ti6Al4V alloy and Mg-Gd-Ca alloy after laser microprocessing has been investigated. The results show that MC3T3-E1 cells have been successfully adhered to the treated surface and optical density are significantly increased due to hybrid micro/nano structure. Anti-bacterial test shows that the anti-bacterial rates against E. coli of laser-treated surface was up to 72%. Meanwhile, water contact angle has been increased from 57.4° to 135.3° indicating the changing of surface wettability from hydrophilic to hydrophobic. Moreover, corrosion test of Mg-Gd-Ca alloy has been conducted, which has been significantly improved after laser microprocessing. The present work showed that laser surface microprocessing could be a promising technique for fabricating different biomedical property surfaces.

Fabrication of porous films from immiscible polymer blends: Role of the surface structure on the cell adhesion

2020 ◽  
Vol 91 ◽  
pp. 106797
Author(s):  
Rayane Akoumeh ◽  
Tamara Elzein ◽  
Enrique Martínez-Campos ◽  
Felipe Reviriego ◽  
Juan Rodríguez-Hernández
Keyword(s):  
Cell Adhesion ◽  
Polymer Blends ◽  
Surface Structure ◽  
Porous Films ◽  
Immiscible Polymer Blends ◽  
Immiscible Polymer

scholarly journals Tool Feed and Burr Size Influence on Wettability of Ti6Al4V Micro End-Milled

2021 ◽  
Vol 6 (3) ◽  
pp. 114-123
Author(s):  
Rodrigo Ferreira ◽  
Gabriel Lopes de Castro Martinelli ◽  
Alessandro Roger Rodrigues ◽  
Reginaldo Teixeira Coelho
Keyword(s):  
Cell Adhesion ◽  
End Milling ◽  
Surface Texturing ◽  
Contact Angles ◽  
Surface Wettability ◽  
Micro Milling ◽  
High Mechanical Strength ◽  
Burr Size ◽  
Micro Channels ◽  
Micro End Milling

Surface texturing, using micro-milling, has promising applications in the industry of medical implants, since it can assist cell adhesion and thus improve osseointegration. Ti6Al4V alloy is used as implant material due to its excellent biocompatibility and high mechanical strength. However, those mechanical properties reduce machinability creating some challenges for micro-milling. The way to initially assess cell adhesion is using surface wettability, usually conducted with water. At the present work, micro-channels were machined in Ti6Al4V by micro end-milling with 500 µm width per 50 µm depth with 1000 µm distant from each other. The effect of feed per tooth (fz) on wettability was analysed and some interesting relations with burrs formed on channel walls were obtained. Values of feed per tooth were 3, 6, 12 and 15 µm. Wettability results showed that slotted surface is more hydrophilic on channel direction, with contact angles around 30° to 43°. In contrast, on the perpendicular direction the surface tends to be hydrophobic with contact angles between 75° and 146°. In addition, contact angle increases (hydrophobic tendency) as feed per tooth increases (along with roughness), even on channel direction. The presence of burrs also tends to disturb wettability results. Therefore, surface wettability depends on channel direction, burr size and tool feed per tooth, as well.

622: Von Hippel-Lindau Inactivation Downregulates the Cell-Cell Adhesion Molecule E Cadherin in Renal Cancer Cells

2005 ◽  
Vol 173 (4S) ◽  
pp. 170-170
Author(s):  
Maxine G. Tran ◽  
Miguel A. Esteban ◽  
Peter D. Hill ◽  
Ashish Chandra ◽  
Tim S. O'Brien ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Cancer Cells ◽  
Renal Cancer ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Von Hippel Lindau ◽  
E Cadherin ◽  
Cell Cell
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