Two-Dimensional Nanomaterials for Biomedical Applications: Emerging Trends and Future Prospects

2015 ◽  
Vol 27 (45) ◽  
pp. 7261-7284 ◽  
Author(s):  
David Chimene ◽  
Daniel L. Alge ◽  
Akhilesh K. Gaharwar
Keyword(s):  
Biomedical Applications ◽  
Two Dimensional ◽  
Future Prospects ◽  
Emerging Trends

Graphene and Graphene-Based Materials in Biomedical Applications

2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic
Keyword(s):  
Tissue Engineering ◽  
Thermal Properties ◽  
Gene Delivery ◽  
Regenerative Medicine ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Two Dimensional ◽  
Drug And Gene Delivery ◽  
Biomedical Fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

Functional Two-Dimensional Black Phosphorus Nanostructures towards Next-Generation Devices

2021 ◽  
Author(s):  
Mengke Wang ◽  
Jun Zhu ◽  
You Zi ◽  
Zheng-Guang Wu ◽  
Haiguo Hu ◽  
...  
Keyword(s):  
Surface Area ◽  
Biomedical Applications ◽  
Black Phosphorus ◽  
Large Surface Area ◽  
Two Dimensional ◽  
Next Generation

In recent years, two-dimensional (2D) black phosphorus (BP) has been widely applied in many fields, such as (opto)electronics, transistors, catalysis and biomedical applications due to its large surface area, tunable...

scholarly journals Biomedical Uses of Sulfobetaine-Based Zwitterionic Materials

2020 ◽  
Vol 02 (04) ◽  
pp. 342-357
Author(s):  
Francesco Zaccarian ◽  
Matthew B. Baker ◽  
Matthew J. Webber
Keyword(s):  
Biomedical Applications ◽  
Foreign Body Reaction ◽  
Inflammatory Responses ◽  
Cellular Adhesion ◽  
Review Of The Literature ◽  
Future Prospects ◽  
Protein Fouling ◽  
Biomedical Device ◽  
The Many ◽  
Hydrophilic Coatings

Protein fouling can render a biomedical device dysfunctional, and also serves to nucleate the foreign body reaction to an implanted material. Hydrophilic coatings have emerged as a commonly applied route to combat interface-mediated complications and promote device longevity and limited inflammatory response. While polyethylene glycol has received a majority of the attention in this regard, coatings based on zwitterionic moieties have been more recently explored. Sulfobetaines in particular constitute one such class of zwitterions explored for use in mitigating surface fouling, and have been shown to reduce protein adsorption, limit cellular adhesion, and promote increased functional lifetimes and limited inflammatory responses when applied to implanted materials and devices. Here, we present a focused review of the literature surrounding sulfobetaine, beginning with an understanding of its chemistry and the methods by which it is applied to the surface of a biomedical device in molecular and polymeric forms, and then advancing to the many early demonstrations of function in a variety of biomedical applications. Finally, we provide some insights into the benefits and challenges presented by its use, as well as some outlook on the future prospects for using this material to improve biomedical device practice by addressing interface-mediated complications.

2D MXene Nanomaterials for Versatile Biomedical Applications: Current Trends and Future Prospects

Small ◽  
2021 ◽  
pp. 2100946
Author(s):  
Beibei Lu ◽  
Zhenye Zhu ◽  
Biyuan Ma ◽  
Wei Wang ◽  
Rongshu Zhu ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Future Prospects ◽  
Current Trends

scholarly journals Stimuli Responsive, Programmable DNA Nanodevices for Biomedical Applications

2021 ◽  
Vol 9 ◽  
Author(s):  
Udisha Singh ◽  
Vinod Morya ◽  
Bhaskar Datta ◽  
Chinmay Ghoroi ◽  
Dhiraj Bhatia
Keyword(s):  
Biomedical Applications ◽  
Recent Progress ◽  
Dna Nanotechnology ◽  
Research Area ◽  
Biological Applications ◽  
Stimuli Responsive ◽  
Future Prospects ◽  
Dna Structures ◽  
Challenges And Opportunities

Of the multiple areas of applications of DNA nanotechnology, stimuli-responsive nanodevices have emerged as an elite branch of research owing to the advantages of molecular programmability of DNA structures and stimuli-responsiveness of motifs and DNA itself. These classes of devices present multiples areas to explore for basic and applied science using dynamic DNA nanotechnology. Herein, we take the stake in the recent progress of this fast-growing sub-area of DNA nanotechnology. We discuss different stimuli, motifs, scaffolds, and mechanisms of stimuli-responsive behaviours of DNA nanodevices with appropriate examples. Similarly, we present a multitude of biological applications that have been explored using DNA nanodevices, such as biosensing, in vivo pH-mapping, drug delivery, and therapy. We conclude by discussing the challenges and opportunities as well as future prospects of this emerging research area within DNA nanotechnology.

scholarly journals Graphene-Based Nanosystems: Versatile Nanotools for Theranostics and Bioremediation

2021 ◽  
Author(s):  
Marlene Lúcio ◽  
Eduarda Fernandes ◽  
Hugo Gonçalves ◽  
Sofia Machado ◽  
Andreia C. Gomes ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Quantum Physics ◽  
Single Layer ◽  
The Body ◽  
Diagnostic Tools ◽  
Honeycomb Lattice ◽  
Two Dimensional ◽  
Advantages And Disadvantages ◽  
Broad Variety ◽  
Imaging Strategy

Since its revolutionary discovery in 2004, graphene— a two-dimensional (2D) nanomaterial consisting of single-layer carbon atoms packed in a honeycomb lattice— was thoroughly discussed for a broad variety of applications including quantum physics, nanoelectronics, energy efficiency, and catalysis. Graphene and graphene-based nanomaterials (GBNs) have also captivated the interest of researchers for innovative biomedical applications since the first publication on the use of graphene as a nanocarrier for the delivery of anticancer drugs in 2008. Today, GBNs have evolved into hybrid combinations of graphene and other elements (e.g., drugs or other bioactive compounds, polymers, lipids, and nanoparticles). In the context of developing theranostic (therapeutic + diagnostic) tools, which combine multiple therapies with imaging strategies to track the distribution of therapeutic agents in the body, the multipurpose character of the GBNs hybrid systems has been further explored. Because each therapy and imaging strategy has inherent advantages and disadvantages, a mixture of complementary strategies is interesting as it will result in a synergistic theranostic effect. The flexibility of GBNs cannot be limited to their biomedical applications and, these nanosystems emerge as a viable choice for an indirect effect on health by their future use as environmental cleaners. Indeed, GBNs can be used in bioremediation approaches alone or combined with other techniques such as phytoremediation. In summary, without ignoring the difficulties that GBNs still present before being deemed translatable to clinical and environmental applications, the purpose of this chapter is to provide an overview of the remarkable potential of GBNs on health by presenting examples of their versatility as nanotools for theranostics and bioremediation.

Omnipotent phosphorene: a next-generation, two-dimensional nanoplatform for multidisciplinary biomedical applications

2018 ◽  
Vol 47 (15) ◽  
pp. 5588-5601 ◽  
Author(s):  
Meng Qiu ◽  
Wen Xiu Ren ◽  
Taeho Jeong ◽  
Miae Won ◽  
Geun Young Park ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Black Phosphorus ◽  
Two Dimensional ◽  
Next Generation ◽  
2D Material ◽  
Significant Attention

Phosphorene, also known as single- or few-layer black phosphorus (FLBP), is a new member of the two-dimensional (2D) material family and has attracted significant attention in recent years for bio-applications.

Lipid extraction by boron nitride nanosheets from liquid-ordered and liquid-disordered nanodomains

Nanoscale ◽  
2018 ◽  
Vol 10 (29) ◽  
pp. 14073-14081 ◽  
Author(s):  
Yonghui Zhang ◽  
Chun Chan ◽  
Zhen Li ◽  
Jiale Ma ◽  
Qiangqiang Meng ◽  
...  
Keyword(s):  
Boron Nitride ◽  
Biomedical Applications ◽  
Lipid Extraction ◽  
Two Dimensional ◽  
Boron Nitride Nanosheets ◽  
Liquid Ordered

Atomically thin boron nitride nanosheets are important two-dimensional nanomaterials with great potential in biomedical applications.

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