A Multifunctional Micellar Nanoplatform with pH-Triggered Cell Penetration and Nuclear Targeting for Effective Cancer Therapy and Inhibition to Lung Metastasis

2018 ◽  
Vol 7 (7) ◽  
pp. 1700974 ◽  
Author(s):  
Yuting Jing ◽  
Xiang Xiong ◽  
Yang Ming ◽  
Jingya Zhao ◽  
Xing Guo ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Lung Metastasis ◽  
Cell Penetration ◽  
Nuclear Targeting ◽  
Effective Cancer Therapy

scholarly journals EGFR-mutant NSCLC presenting with stroke and massive systemic embolization as the first manifestation: case report

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zheng Wang ◽  
Jiangyong Miao ◽  
Lina Wang ◽  
Ying Liu ◽  
Hui Ji ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Cancer Therapy ◽  
Acute Ischemic Stroke ◽  
Oral Anticoagulants ◽  
Initial Manifestation ◽  
Arterial Thromboembolism ◽  
Systemic Embolization ◽  
Effective Cancer Therapy

Abstract Background Presentation with massive systemic embolization as the initial manifestation of occult malignancy is infrequent. The standard management of cancer-related arterial thromboembolism has not yet been established. Case presentation We described a case of Trousseau’s syndrome resulting in acute ischemic stroke concomitant with multiple embolizations in the spleen and kidney during oral administration of dabigatran for pulmonary embolism preceding the diagnosis of a malignant tumor. A cancer-related hypercoagulable state was suspected because the patient was admitted to the neurology department due to acute ischemic stroke with three territory infarcts on diffusion-weighted imaging (DWI) in the absence of identifiable conventional risk factors and brain vessel narrowing. The patient was subsequently diagnosed with epidermal growth factor receptor (EGFR) mutation–positive non-small-cell lung cancer (NSCLC) (stage IV) with pleural metastasis. Administration of low-molecular-weight heparin followed by long-term dabigatran under effective cancer therapy comprising gefitinib and subsequent chemotherapy did not cause stroke relapse during the 1-year follow-up. Conclusions This case suggests that cancer-related hypercoagulability should be considered an important etiology for stroke patients who develop unexplained disseminated acute cerebral infarction without conventional stroke risk factors, especially concomitant with multiple organ embolization. Novel oral anticoagulants may be an alternative therapy for the long-term management of cancer-related arterial thromboembolism under effective cancer therapy.

Facile Preparation of Cationic Gold Nanoparticle-Bioconjugates for Cell Penetration and Nuclear Targeting

ACS Nano ◽  
2012 ◽  
Vol 6 (9) ◽  
pp. 7692-7702 ◽  
Author(s):  
Isaac Ojea-Jiménez ◽  
Lorena García-Fernández ◽  
Julia Lorenzo ◽  
Victor F. Puntes
Keyword(s):  
Gold Nanoparticle ◽  
Cell Penetration ◽  
Nuclear Targeting ◽  
Facile Preparation ◽  
Cationic Gold

scholarly journals Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer-Associated Fibroblast Activation

2015 ◽  
Vol 128 (3) ◽  
pp. 1062-1067 ◽  
Author(s):  
Tianjiao Ji ◽  
Ying Zhao ◽  
Yanping Ding ◽  
Jing Wang ◽  
Ruifang Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Fibroblast Activation ◽  
Cancer Associated Fibroblast ◽  
Effective Cancer Therapy

Conceptually Novel Black Phosphorus/Cellulose Hydrogels as Promising Photothermal Agents for Effective Cancer Therapy

2018 ◽  
Vol 7 (7) ◽  
pp. 1701510 ◽  
Author(s):  
Chenyang Xing ◽  
Shiyou Chen ◽  
Meng Qiu ◽  
Xin Liang ◽  
Quan Liu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Black Phosphorus ◽  
Effective Cancer Therapy

Hollow Polypyrrole Nanospindles for Highly Effective Cancer Therapy

ChemPlusChem ◽  
2018 ◽  
Vol 83 (12) ◽  
pp. 1127-1134 ◽  
Author(s):  
Yixin Chen ◽  
Siyuan Xiang ◽  
Lu Wang ◽  
Mingyue Wang ◽  
Congcong Wang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Highly Effective ◽  
Effective Cancer Therapy

High-Throughput Synthesis of Single-Layer MoS2 Nanosheets as a Near-Infrared Photothermal-Triggered Drug Delivery for Effective Cancer Therapy

ACS Nano ◽  
2014 ◽  
Vol 8 (7) ◽  
pp. 6922-6933 ◽  
Author(s):  
Wenyan Yin ◽  
Liang Yan ◽  
Jie Yu ◽  
Gan Tian ◽  
Liangjun Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
High Throughput ◽  
Near Infrared ◽  
Single Layer ◽  
Mos2 Nanosheets ◽  
Effective Cancer Therapy

scholarly journals Corrigendum: Hollow Polypyrrole Nanospindles for Highly Effective Cancer Therapy

ChemPlusChem ◽  
2021 ◽  
Author(s):  
Yixin Chen ◽  
Siyuan Xiang ◽  
Lu Wang ◽  
Mingyue Wang ◽  
Congcong Wang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Highly Effective ◽  
Effective Cancer Therapy

scholarly journals Mono-arginine Cholesterol-based Small Lipid Nanoparticles as a Systemic siRNA Delivery Platform for Effective Cancer Therapy

Theranostics ◽  
2016 ◽  
Vol 6 (2) ◽  
pp. 192-203 ◽  
Author(s):  
Jinju Lee ◽  
Phei Er Saw ◽  
Vipul Gujrati ◽  
Yonghyun Lee ◽  
Hyungjun Kim ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Sirna Delivery ◽  
Lipid Nanoparticles ◽  
Delivery Platform ◽  
Effective Cancer Therapy
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