High-Throughput Synthesis of Single-Layer MoS2 Nanosheets as a Near-Infrared Photothermal-Triggered Drug Delivery for Effective Cancer Therapy

ACS Nano ◽  
2014 ◽  
Vol 8 (7) ◽  
pp. 6922-6933 ◽  
Author(s):  
Wenyan Yin ◽  
Liang Yan ◽  
Jie Yu ◽  
Gan Tian ◽  
Liangjun Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
High Throughput ◽  
Near Infrared ◽  
Single Layer ◽  
Mos2 Nanosheets ◽  
Effective Cancer Therapy

scholarly journals Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy

2018 ◽  
Vol 115 (3) ◽  
pp. 501-506 ◽  
Author(s):  
Meng Qiu ◽  
Dou Wang ◽  
Weiyuan Liang ◽  
Liping Liu ◽  
Yin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Black Phosphorus ◽  
Deep Penetration ◽  
Nir Light

A biodegradable drug delivery system (DDS) is one the most promising therapeutic strategies for cancer therapy. Here, we propose a unique concept of light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy. A photosensitizer converts light into heat that softens and melts drug-loaded hydrogel-based nanostructures. Drug release rates can be accurately controlled by light intensity, exposure duration, BP concentration, and hydrogel composition. Owing to sufficiently deep penetration of near-infrared (NIR) light through tissues, our BP-based system shows high therapeutic efficacy for treatment of s.c. cancers. Importantly, our drug delivery system is completely harmless and degradable in vivo. Together, our work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs. If these findings are successfully translated into the clinic, millions of patients with cancer will benefit from our work.

scholarly journals Hyaluronic Acid-Conjugated Carbon Nanomaterials for Enhanced Tumour Targeting Ability

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 48
Author(s):  
Oisin Kearns ◽  
Adalberto Camisasca ◽  
Silvia Giordani
Keyword(s):  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Carbon Nanomaterials ◽  
Graphene Quantum Dots ◽  
Tumour Volume ◽  
The Novel ◽  
Targeting Ability

Hyaluronic acid (HA) has been implemented for chemo and photothermal therapy to target tumour cells overexpressing the CD44+ receptor. HA-targeting hybrid systems allows carbon nanomaterial (CNM) carriers to efficiently deliver anticancer drugs, such as doxorubicin and gemcitabine, to the tumour sites. Carbon nanotubes (CNTs), graphene, graphene oxide (GO), and graphene quantum dots (GQDs) are grouped for a detailed review of the novel nanocomposites for cancer therapy. Some CNMs proved to be more successful than others in terms of stability and effectiveness at removing relative tumour volume. While the literature has been focused primarily on the CNTs and GO, other CNMs such as carbon nano-onions (CNOs) proved quite promising for targeted drug delivery using HA. Near-infrared laser photoablation is also reviewed as a primary method of cancer therapy—it can be used alone or in conjunction with chemotherapy to achieve promising chemo-photothermal therapy protocols. This review aims to give a background into HA and why it is a successful cancer-targeting component of current CNM-based drug delivery systems.

scholarly journals Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy

Theranostics ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. 2217-2228 ◽  
Author(s):  
Xinyu Song ◽  
Xiaoyue Han ◽  
Fabiao Yu ◽  
Xiaoyu Zhang ◽  
Lingxin Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Monitoring Drug ◽  
Lung Cancer Therapy

scholarly journals Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy

2017 ◽  
Vol 56 (39) ◽  
pp. 11896-11900 ◽  
Author(s):  
Wei Tao ◽  
Xiaoyuan Ji ◽  
Xiaoding Xu ◽  
Mohammad Ariful Islam ◽  
Zhongjun Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Effective Cancer Therapy

scholarly journals Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy

2017 ◽  
Vol 129 (39) ◽  
pp. 12058-12062 ◽  
Author(s):  
Wei Tao ◽  
Xiaoyuan Ji ◽  
Xiaoding Xu ◽  
Mohammad Ariful Islam ◽  
Zhongjun Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Effective Cancer Therapy

scholarly journals Innentitelbild: Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy (Angew. Chem. 39/2017)

2017 ◽  
Vol 129 (39) ◽  
pp. 11816-11816
Author(s):  
Wei Tao ◽  
Xiaoyuan Ji ◽  
Xiaoding Xu ◽  
Mohammad Ariful Islam ◽  
Zhongjun Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Effective Cancer Therapy

Stimuli-responsive Drug Delivery Nanocarriers in the Treatment of Breast Cancer

2020 ◽  
Vol 27 (15) ◽  
pp. 2494-2513 ◽  
Author(s):  
João A. Oshiro-Júnior ◽  
Camila Rodero ◽  
Gilmar Hanck-Silva ◽  
Mariana R. Sato ◽  
Renata Carolina Alves ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Stimuli Responsive ◽  
Breast Cancer Therapy ◽  
Physical Stimuli ◽  
Pharmaceutical Properties

Stimuli-responsive drug-delivery nanocarriers (DDNs) have been increasingly reported in the literature as an alternative for breast cancer therapy. Stimuli-responsive DDNs are developed with materials that present a drastic change in response to intrinsic/chemical stimuli (pH, redox and enzyme) and extrinsic/physical stimuli (ultrasound, Near-infrared (NIR) light, magnetic field and electric current). In addition, they can be developed using different strategies, such as functionalization with signaling molecules, leading to several advantages, such as (a) improved pharmaceutical properties of liposoluble drugs, (b) selectivity with the tumor tissue decreasing systemic toxic effects, (c) controlled release upon different stimuli, which are all fundamental to improving the therapeutic effectiveness of breast cancer treatment. Therefore, this review summarizes the use of stimuli-responsive DDNs in the treatment of breast cancer. We have divided the discussions into intrinsic and extrinsic stimuli and have separately detailed them regarding their definitions and applications. Finally, we aim to address the ability of these stimuli-responsive DDNs to control the drug release in vitro and the influence on breast cancer therapy, evaluated in vivo in breast cancer models.

scholarly journals ROS-Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy

2017 ◽  
Vol 29 (33) ◽  
pp. 1700141 ◽  
Author(s):  
Xiaoding Xu ◽  
Phei Er Saw ◽  
Wei Tao ◽  
Yujing Li ◽  
Xiaoyuan Ji ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Effective Cancer Therapy

Black phosphorus analogue tin sulfide nanosheets: synthesis and application as near-infrared photothermal agents and drug delivery platforms for cancer therapy

2018 ◽  
Vol 6 (29) ◽  
pp. 4747-4755 ◽  
Author(s):  
Zhongjian Xie ◽  
Dou Wang ◽  
Taojian Fan ◽  
Chenyang Xing ◽  
Zhongjun Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Drug Loading ◽  
Black Phosphorus ◽  
Loading Capacity ◽  
Tin Sulfide ◽  
High Drug ◽  
High Drug Loading

Black phosphorus analogue tin sulfide nanosheets as photothermal and drug delivery agents with high drug loading capacity for cancer therapy.

Sign in / Sign up

Export Citation Format

Share Document