scholarly journals Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation

2016 ◽  
Vol 5 (21) ◽  
pp. 2758-2764 ◽  
Author(s):  
Lei Cai ◽  
Ruby E. Dewi ◽  
Andrew B. Goldstone ◽  
Jeffrey E. Cohen ◽  
Amanda N. Steele ◽  
...  
Keyword(s):  
Stem Cell ◽  
Network Formation ◽  
Injectable Hydrogels

Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours

2005 ◽  
Vol 47 (1) ◽  
pp. 48-56 ◽  
Author(s):  
C E Hoei-Hansen ◽  
K Almstrup ◽  
J E Nielsen ◽  
S Brask Sonne ◽  
N Graem ◽  
...  
Keyword(s):  
Stem Cell ◽  
Germ Cell ◽  
Carcinoma In Situ ◽  
Germ Cell Tumours ◽  
Testicular Carcinoma ◽  
Stem Cell Pluripotency ◽  
Pluripotency Factor

scholarly journals Fabrication of injectable hydrogels based on poly(l-glutamic acid) and chitosan

RSC Advances ◽  
2017 ◽  
Vol 7 (28) ◽  
pp. 17005-17019 ◽  
Author(s):  
Shifeng Yan ◽  
Taotao Wang ◽  
Xing Li ◽  
Yuhang Jian ◽  
Kunxi Zhang ◽  
...  
Keyword(s):  
Schiff Base ◽  
Glutamic Acid ◽  
Crosslinking Reaction ◽  
Injectable Hydrogels ◽  
Oppositely Charged

The in situ forming hydrogels based on oppositely charged poly(l-glutamic acid) (PLGA) and chitosan (CS) were prepared via a Schiff base crosslinking reaction.

scholarly journals Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44

2012 ◽  
Vol 3 (6) ◽  
pp. 1186-1190 ◽  
Author(s):  
HIDEHIRO TAJIMA ◽  
TETSUO OHTA ◽  
HIROHISA KITAGAWA ◽  
KOICHI OKAMOTO ◽  
SEISHO SAKAI ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Stem Cell ◽  
Neoadjuvant Chemotherapy ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Apoptosis Marker

In Situ Methods for Identifying the Stem Cell of the Normal and Cancerous Breast

2014 ◽  
pp. 151-182 ◽  
Author(s):  
Yanrong Su ◽  
Pedro J. Gutiérrez Diez ◽  
Julia Santucci-Pereira ◽  
Irma H. Russo ◽  
Jose Russo
Keyword(s):  
Stem Cell ◽  
In Situ Methods

scholarly journals Adipose-Derived Mesenchymal Stromal/Stem Cells: Tissue Localization, Characterization, and Heterogeneity

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Patrick C. Baer ◽  
Helmut Geiger
Keyword(s):  
Stem Cells ◽  
Adipose Tissue ◽  
Stem Cell ◽  
Cultured Cells ◽  
Current Knowledge ◽  
High Plasticity ◽  
Culture Methods ◽  
Tissue Localization ◽  
Stromal Stem Cells

Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal stromal/stem cells (ASCs) yields a high amount of stem cells, which is essential for stem-cell-based therapies and tissue engineering. Several studies have provided evidence that ASCs in situ reside in a perivascular niche, whereas the exact localization of ASCs in native adipose tissue is still under debate. ASCs are isolated by their capacity to adhere to plastic. Nevertheless, recent isolation and culture techniques lack standardization. Cultured cells are characterized by their expression of characteristic markers and their capacity to differentiate into cells from meso-, ecto-, and entodermal lineages. ASCs possess a high plasticity and differentiate into various cell types, including adipocytes, osteoblasts, chondrocytes, myocytes, hepatocytes, neural cells, and endothelial and epithelial cells. Nevertheless, recent studies suggest that ASCs are a heterogeneous mixture of cells containing subpopulations of stem and more committed progenitor cells. This paper summarizes and discusses the current knowledge of the tissue localization of ASCs in situ, their characterization and heterogeneityin vitro, and the lack of standardization in isolation and culture methods.

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