Trap Effect of Three-Dimensional Fibers Network for High Efficient Cancer-Cell Capture

2015 ◽  
Vol 4 (6) ◽  
pp. 838-843 ◽  
Author(s):  
Lan Ma ◽  
Gao Yang ◽  
Nü Wang ◽  
Pengchao Zhang ◽  
Fengyun Guo ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Three Dimensional ◽  
Cell Capture ◽  
High Efficient

scholarly journals Three‐Dimensional Visualization of Subcellular Dynamics of Cancer Cell Destruction on Therapeutic Nanodrug Treatment

2021 ◽  
pp. 2000145
Author(s):  
Sreejith Raveendran ◽  
Anindito Sen ◽  
Toru Maekawa ◽  
D. Sakthi Kumar
Keyword(s):  
Cancer Cell ◽  
Three Dimensional ◽  
Cell Destruction

scholarly journals Folic acid modified electrospun poly(vinyl alcohol)/polyethyleneimine nanofibers for cancer cell capture applications

2016 ◽  
Vol 34 (6) ◽  
pp. 755-765 ◽  
Author(s):  
Zhang-yu Fan ◽  
Yi-li Zhao ◽  
Xiao-yue Zhu ◽  
Yu Luo ◽  
Ming-wu Shen ◽  
...  
Keyword(s):  
Folic Acid ◽  
Cancer Cell ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Cell Capture

PDMS micropillar-based microchip for efficient cancer cell capture

RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 52161-52166 ◽  
Author(s):  
Jingrong Xiao ◽  
Weiqi He ◽  
Zhengtao Zhang ◽  
Weiying Zhang ◽  
Yiping Cao ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Microfluidic Device ◽  
Cell Capture

We introduce a micropillar-based microfluidic device for efficient and rapid cancer cell capture.

Abstract 020: Cell-sheet-based Bioengineered Human Cardiac Tissue Using Pluripotent Stem Cells For Heart Repair And Disease Models

2013 ◽  
Vol 113 (suppl_1) ◽  
Author(s):  
Katsuhisa Matsuura ◽  
Tatsuya Shimizu ◽  
Nobuhisa Hagiwara ◽  
Teruo Okano
Keyword(s):  
Cardiac Tissue ◽  
Subcutaneous Tissue ◽  
Cell Sheet ◽  
Three Dimensional ◽  
Embryoid Bodies ◽  
Cardiac Differentiation ◽  
Cardiac Cell ◽  
Cell Sheets ◽  
High Efficient ◽  
Human Cardiac Tissue

We have developed an original scaffold-free tissue engineering approach, “cell sheet engineering”, and this technology has been already applied to regenerative medicine of various organs including heart. As the bioengineered three-dimensional cardiac tissue is expected to not only function for repairing the broad injured heart but also to be the practicable heart tissue models, we have developed the cell sheet-based perfusable bioengineered three-dimensional cardiac tissue. Recently we have also developed the unique suspension cultivation system for the high-efficient cardiac differentiation of human iPS cells. Fourteen-day culture with the serial treatments of suitable growth factors and a small compound in this stirring system with the suitable dissolved oxygen concentration produced robust embryoid bodies that showed the spontaneous beating and were mainly composed of cardiomyocytes (~80%). When these differentiated cells were cultured on temperature-responsive culture dishes after the enzymatic dissociation, the spontaneous and synchronous beating was observed accompanied with the intracellular calcium influx all over the area even after cell were detached from culture dishes as cell sheets by lowering the culture temperature. The cardiac cell sheets were mainly composed of cardiomyocytes (~80%) and partially mural cells (~20%). Furthermore, extracellular action potential propagation was observed between cell sheets when two cardiac cell sheets were partially overlaid, and this propagation was inhibited by the treatment with some anti-arrhythmic drugs. When the triple layered cardiac tissue was transplanted onto the subcutaneous tissue of nude rats, the spontaneous pulsation was observed over 2 months and engrafted cardiomyocytes were vascularized with the host tissue-derived endothelial cells. These findings suggest that cardiac cell sheets formed by hiPSC-derived cardiomyocytes might have sufficient properties for the creation of thickened cardiac tissue. Now we are developing the vascularized thickened human cardiac tissue by the repeated layering of cardiac cell sheets on the artificial vascular bed in vitro.

Three‐dimensional cancer cell culture in high‐yield multiscale scaffolds by shear spinning

2018 ◽  
Vol 35 (2) ◽  
pp. e2750 ◽  
Author(s):  
Ahmed A. Ahmed ◽  
CJ Luo ◽  
Sandra Perez‐Garrido ◽  
Connor R. Browse ◽  
Christopher Thrasivoulou ◽  
...  
Keyword(s):  
Cell Culture ◽  
Cancer Cell ◽  
Three Dimensional ◽  
High Yield ◽  
Shear Spinning

scholarly journals Transparent, biocompatible nanostructured surfaces for cancer cell capture and culture

2014 ◽  
pp. 2569 ◽  
Author(s):  
Bin Xiong ◽  
Boran Cheng ◽  
Zhaobo He ◽  
Libo Zhao ◽  
Yuanyuan Chen ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Cell Capture ◽  
Nanostructured Surfaces
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