scholarly journals Extracellular Matrix Remodelling: Obesity‐Associated Adipose Stromal Cells Promote Breast Cancer Invasion through Direct Cell Contact and ECM Remodeling (Adv. Funct. Mater. 48/2020)

2020 ◽  
Vol 30 (48) ◽  
pp. 2070320
Author(s):  
Lu Ling ◽  
Jeffrey A. Mulligan ◽  
Yunxin Ouyang ◽  
Adrian A. Shimpi ◽  
Rebecca M. Williams ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Extracellular Matrix ◽  
Stromal Cells ◽  
Cell Contact ◽  
Adipose Stromal Cells ◽  
Ecm Remodeling ◽  
Breast Cancer Invasion ◽  
Extracellular Matrix Remodelling ◽  
Direct Cell ◽  
Promote Breast Cancer

scholarly journals Obesity‐Associated Adipose Stromal Cells Promote Breast Cancer Invasion through Direct Cell Contact and ECM Remodeling

2020 ◽  
Vol 30 (48) ◽  
pp. 1910650 ◽  
Author(s):  
Lu Ling ◽  
Jeffrey A. Mulligan ◽  
Yunxin Ouyang ◽  
Adrian A. Shimpi ◽  
Rebecca M. Williams ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stromal Cells ◽  
Cancer Invasion ◽  
Cell Contact ◽  
Adipose Stromal Cells ◽  
Ecm Remodeling ◽  
Breast Cancer Invasion ◽  
Direct Cell ◽  
Promote Breast Cancer

scholarly journals Tumor-Resident Stromal Cells Promote Breast Cancer Invasion through Regulation of the Basal Phenotype

2020 ◽  
Vol 18 (11) ◽  
pp. 1615-1622 ◽  
Author(s):  
Christopher J. Hanley ◽  
Elodie Henriet ◽  
Orit Katarina Sirka ◽  
Gareth J. Thomas ◽  
Andrew J. Ewald
Keyword(s):  
Breast Cancer ◽  
Stromal Cells ◽  
Cancer Invasion ◽  
Basal Phenotype ◽  
Breast Cancer Invasion ◽  
Promote Breast Cancer

scholarly journals Prostaglandin E2 Inhibits p53 in Human Breast Adipose Stromal Cells: A Novel Mechanism for the Regulation of Aromatase in Obesity and Breast Cancer

2015 ◽  
Vol 75 (4) ◽  
pp. 645-655 ◽  
Author(s):  
Xuyi Wang ◽  
Maria M. Docanto ◽  
Hironobu Sasano ◽  
Camden Lo ◽  
Evan R. Simpson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prostaglandin E2 ◽  
Stromal Cells ◽  
Human Breast ◽  
Adipose Stromal Cells ◽  
Breast Adipose

scholarly journals The Origins and Generation of Cancer-Associated Mesenchymal Stromal Cells: An Innovative Therapeutic Target for Solid Tumors

2021 ◽  
Vol 11 ◽  
Author(s):  
Wei Li ◽  
Jin Yang ◽  
Ping Zheng ◽  
Haining Li ◽  
Shaolin Zhao
Keyword(s):  
Cancer Therapy ◽  
Tumor Cells ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Chemotherapy Resistance ◽  
Tissue Type ◽  
Cell Contact ◽  
Local Resident ◽  
Anti Cancer ◽  
Direct Cell

Cancer-associated mesenchymal stromal cells (CA-MSCs) have been isolated from various types of tumors and are characterized by their vigorous pro-tumorigenic functions. However, very little is known about the origins and generating process of CA-MSCs, which may facilitate the identification of biomarkers for diagnosis or innovative targets for anti-cancer therapy to restrain the tumor growth, spread and chemotherapy resistance. Current evidences have indicated that both distally recruited and local resident MSCs are the primary origins of CA-MSCs. In a tissue type-dependent mode, tumor cells together with the TME components prompt the malignant transition of tumor “naïve” MSCs into CA-MSCs in a direct cell-to-cell contact, paracrine or exosome-mediated manner. In this review, we discuss the transition of phenotypes and functions of naïve MSCs into CA-MSCs influenced by tumor cells or non-tumor cells in the TME. The key areas remaining poorly understood are also highlighted and concluded herein.

Adipose Stromal Cells Differentiate Along a Smooth Muscle Lineage Pathway Upon Endothelial Cell Contact via Induction of Activin A

2014 ◽  
Vol 115 (9) ◽  
pp. 800-809 ◽  
Author(s):  
Stephanie Merfeld-Clauss ◽  
Ivan P. Lupov ◽  
Hongyan Lu ◽  
Dongni Feng ◽  
Peter Compton-Craig ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Endothelial Cell ◽  
Stromal Cells ◽  
Activin A ◽  
Cell Contact ◽  
Adipose Stromal Cells

scholarly journals Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells

Oncogene ◽  
2009 ◽  
Vol 28 (30) ◽  
pp. 2745-2755 ◽  
Author(s):  
M Walter ◽  
S Liang ◽  
S Ghosh ◽  
P J Hornsby ◽  
R Li
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Stromal Cells ◽  
Interleukin 6 ◽  
Breast Cancer Cells ◽  
Migration And Invasion ◽  
Adipose Stromal Cells

scholarly journals Association of obesity and circulating adipose stromal cells among breast cancer survivors

2014 ◽  
Vol 41 (5) ◽  
pp. 2907-2916 ◽  
Author(s):  
Sagar Ghosh ◽  
Daniel Hughes ◽  
Dorothy Long Parma ◽  
Amelie Ramirez ◽  
Rong Li
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Stromal Cells ◽  
Breast Cancer Survivors ◽  
Adipose Stromal Cells
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