Strong Photoacoustic Signal Enhancement by Coating Gold Nanoparticles with Melanin for Biomedical Imaging

2017 ◽  
Vol 28 (7) ◽  
pp. 1705607 ◽  
Author(s):  
Tatjana Repenko ◽  
Anne Rix ◽  
Alexander Nedilko ◽  
Jonas Rose ◽  
Alina Hermann ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Biomedical Imaging ◽  
Photoacoustic Signal ◽  
Signal Enhancement

Photoacoustic signal enhancement at visible and X-ray wavelengths

1991 ◽  
Vol 52 (1) ◽  
pp. 8-13
Author(s):  
S. J. Isak ◽  
B. A. Garland ◽  
E. M. Eyring ◽  
J. P. Kirkland ◽  
R. A. Neiser
Keyword(s):  
Photoacoustic Signal ◽  
Signal Enhancement ◽  
X Ray

Tailored porphyrin–gold nanoparticles for biomedical applications

2019 ◽  
Vol 23 (07n08) ◽  
pp. 766-780 ◽  
Author(s):  
Madalina E. Grigore ◽  
Rodica-M. Ion ◽  
Lorena Iancu ◽  
Ramona M. Grigorescu
Keyword(s):  
Gold Nanoparticles ◽  
Biomedical Applications ◽  
Biomedical Imaging ◽  
Synthesis Methods ◽  
Triplet States ◽  
Medical Field ◽  
Yield Efficiency ◽  
Quantum Yield Efficiency ◽  
Synthesis Approach ◽  
Functionalized Aunps

In this review we present an updated survey of the main synthesis methods of gold nanoparticles (AuNPs) in order to obtain various tailored nanosystems for biomedical imaging. The synthesis approach significantly impacts on the AuNPs properties such as surface chemistry, biocompatibility and cytotoxicity. In recent years, nanomedicine emphasized the development of functionalized AuNPs for biomedical imaging. AuNPs are a good option for used as delivery photosensitizer agents for PDT of cancer. For example, the complex formed from AuNPs functionalized with PEGylate porphyrins presents several advantages in the medical field such as a better use in photodynamic therapy because of high triplet states and singlet oxygen quantum yield efficiency of porphyrin molecules.

scholarly journals Exploiting Nonlinear Photoacoustic Signal Generation in Gold Nanospheres for Selective Detection in Serial 3D PA Tomography

2018 ◽  
Vol 4 (12) ◽  
pp. 146 ◽  
Author(s):  
Susanne Schrof ◽  
Genny Pang ◽  
Jens Buchmann ◽  
Jan Laufer
Keyword(s):  
Gold Nanoparticles ◽  
Spatial Distribution ◽  
Signal Amplitude ◽  
Photoacoustic Signal ◽  
Selective Detection ◽  
Gold Nanospheres ◽  
Robust Detection ◽  
Tissue Phantom ◽  
Gold Nanosphere ◽  
Background Contrast

The photoacoustic (PA) signal amplitude measured in gold nanosphere suspensions has been shown to increase nonlinearly with the incident excitation fluence. In this work, this effect is exploited to recover the spatial distribution of gold nanoparticles in tomographic 3D photoacoustic (PA) images against the background contrast provided by absorbers that exhibit a linear relationship between the PA signal amplitude and the fluence. Serial tomographic PA images of a tissue phantom containing gold nanospheres and a tissue-mimicking absorber were acquired. By assessing the linearity of the PA intensity voxel by voxel, the spatial distribution of the gold nanosphere suspension was recovered. The method is shown to enable the robust detection of gold nanoparticles.

Ternary covalent conjugate (antibody–gold nanoparticle–peroxidase) for signal enhancement in enzyme immunoassay

RSC Advances ◽  
2016 ◽  
Vol 6 (54) ◽  
pp. 48827-48833 ◽  
Author(s):  
M. M. Vdovenko ◽  
N. A. Byzova ◽  
A. V. Zherdev ◽  
B. B. Dzantiev ◽  
I. Yu. Sakharov
Keyword(s):  
Gold Nanoparticles ◽  
Horseradish Peroxidase ◽  
Enzyme Immunoassay ◽  
Gold Nanoparticle ◽  
Signal Enhancement ◽  
Enzyme Content ◽  
High Enzyme ◽  
Covalently Bound

A synthesis of a new horseradish peroxidase (HRP) conjugate and antibody covalently bound with gold nanoparticles (GNPs) with a high enzyme content was first developed.

The effect of surface charge of plasmonic gold nanoparticles on photoacoustic signal

2014 ◽  
Author(s):  
Miya Ishihara ◽  
Takeshi Hirasawa ◽  
Shinpei Okawa ◽  
Ryota Sato ◽  
Yasuteru Urano ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Surface Charge ◽  
Photoacoustic Signal ◽  
Effect Of Surface
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