Organization of the Bacterial Chromosome

2006 ◽  
pp. 29-50 ◽  
Keyword(s):  
Bacterial Chromosome

scholarly journals Ability of a bacterial chromosome segment to invert is dictated by included material rather than flanking sequence.

Genetics ◽  
1991 ◽  
Vol 129 (4) ◽  
pp. 1021-1032 ◽  
Author(s):  
M J Mahan ◽  
J R Roth
Keyword(s):  
Homologous Recombination ◽  
Parent Strain ◽  
Genetic Material ◽  
Chromosomal Inversion ◽  
Chromosome Segment ◽  
Bacterial Chromosome ◽  
Flanking Sequence ◽  
Flanking Sequences ◽  
Almost All

Abstract Homologous recombination between sequences present in inverse order within the same chromosome can result in inversion formation. We have previously shown that inverse order sequences at some sites (permissive) recombine to generate the expected inversion; no inversions are found when the same inverse order sequences flank other (nonpermissive) regions of the chromosome. In hopes of defining how permissive and nonpermissive intervals are determined, we have constructed a strain that carries a large chromosomal inversion. Using this inversion mutant as the parent strain, we have determined the "permissivity" of a series of chromosomal sites for secondary inversions. For the set of intervals tested, permissivity seems to be dictated by the nature of the genetic material present within the chromosomal interval being tested rather than the flanking sequences or orientation of this material in the chromosome. Almost all permissive intervals include the origin or terminus of replication. We suggest that the rules for recovery of inversions reflect mechanistic restrictions on the occurrence of inversions rather than lethal consequences of the completed rearrangement.

Tuning the Expression Level of a Gene Located on a Bacterial Chromosome

2005 ◽  
Vol 39 (5) ◽  
pp. 719-726 ◽  
Author(s):  
J. I. Katashkina ◽  
A. Yu. Skorokhodova ◽  
D. V. Zimenkov ◽  
A. Yu. Gulevich ◽  
N. I. Minaeva ◽  
...  
Keyword(s):  
Expression Level ◽  
Bacterial Chromosome

Bacterial Chromosome Dynamics

Science ◽  
2003 ◽  
Vol 301 (5634) ◽  
pp. 780-785 ◽  
Author(s):  
D. J. Sherratt
Keyword(s):  
Bacterial Chromosome ◽  
Chromosome Dynamics
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