Cobalamin deficiency and red blood cell volume distribution width

1990 ◽  
Vol 150 (4) ◽  
pp. 910b-911
Author(s):  
M. F. Stern
1989 ◽  
Vol 12 (3) ◽  
pp. 170-174 ◽  
Author(s):  
D. Docci ◽  
C. Delvecchio ◽  
C. Gollini ◽  
F. Turci ◽  
L. Baldrati ◽  
...  

Red blood cell volume distribution width (RDW) was obtained with the Coulter counter in 60 haemodialysis patients and 55 normal individuals. RDW tended to be higher in the former and the degree of increase was to some extent correlated with the underlying nephropathy. Although RDW failed to correlate with conventional tests of iron status, it was observed that iron administration could produce a decrease toward normal in RDW and a parallel increase in haemoglobin when the initial RDW was increased. In contrast, the response to iron was negligible in the patients with normal RDW basally. It was concluded that high RDW is an acceptable indicator of iron deficiency in haemodialysis patients.


1988 ◽  
Vol 66 (7) ◽  
pp. 1589-1596 ◽  
Author(s):  
M. R. A. Heieis ◽  
David R. Jones

Blood is the major oxygen store in ducks forced to dive, and underwater endurance depends on how much of this store can be used by oxygen-sensitive tissues such as the heart and brain. Arterial injection of macroaggregated albumin labelled with technetium-99 m, which is trapped and held by capillaries, showed that circulation in dives was restricted to the thoracic and head areas. However, tracing red blood cells labelled with technetium-99 m as they were injected during dives showed not only that the time required for the activity to reach equilibrium was 4–10 times longer than when labelled cells were injected into resting ducks but also that blood flow continued in the leg and visceral regions. Tracing red blood cells, labelled with technetium-99 m and mixed in the circulation before a dive, during the dive showed that labelled red blood cells were redistributed from the peripheral and visceral areas to the central cardiovascular area. Measurement of circulating red blood cell volume during and after diving showed that, on average, 75.24 ± 4.56% of the total red blood cell volume was circulated during forced submergence. Hence, in forced dives, red blood cell volume is positioned in such a manner that the heart and brain have access to the oxygen stored there, and the residual blood flow in the periphery ensures that most of the red blood cell volume is circulated.


2021 ◽  
Vol 71 (2) ◽  
pp. 575-78
Author(s):  
Sahar Rabbani ◽  
Muhammad Farooq ◽  
Samina Naeem ◽  
, Muhammad Abdul Naeem ◽  
Nasir Uddin ◽  
...  

Objective: To find out the correlation between the red blood cell and platelet indices in patients presenting with iron deficiency anemia at a tertiary care hospital of Pakistan. Study Design: Cross-sectional study. Place and Duration of Study: Department of Hematology, Combined Military Hospital Lahore, from Sep 2018 to Mar 2019. Methodology: The patients of age 1-70 years of either gender presenting with IDA were included in the study. The blood sample of patients were sent to laboratory to assess the red blood cell and platelet indices. SPSS-23 was used to analyze data. Results: Two hundred and seven patients fulfilling the inclusion criteria were included in this study. The mean age was 25.6 ±17.8years. Correlation was weak and insignificant between haemoglobin and packed cell volume (r=-0.385**, p<0.01), haemoglobin and mean cell volume (r=-0.225**, p<0.01), packed cell volume and mean cell haemoglobin (r =0.263**, p<0.01), & mean cell haemoglobin and mean platelet volume (r=0.143*, p<0.05). Correlation was moderate and significant between platelet distribution width and mean platelet volume (r=0.511**) & platelet distribution width and platelet large cell ratio (0.502**, p<0.01). Correlation was strong between mean platelet volume and platelet large cell ratio (r=0.759**, p<0.01). Conclusion: In conclusion, there was significant relation between red blood cell and platelets indices in iron deficiency anemia. Furthermore, haemoglobin and packed cell volume are weekly correlated, platelet distribution width and mean platelet volume are moderately correlated and mean platelet volume and platelet large cell ratio are strongly correlated.


Urology ◽  
2003 ◽  
Vol 61 (3) ◽  
pp. 507-511 ◽  
Author(s):  
Xavier Gamé ◽  
Michel Soulié ◽  
Anne-Marie Fontanilles ◽  
Jean-Michel Benoit ◽  
J.ol-Xavier Corberand ◽  
...  

2017 ◽  
Vol 86 (4) ◽  
pp. 385-391
Author(s):  
Olga Aniołek ◽  
Agnieszka Barc ◽  
Anna Jarosińska ◽  
Zdzisław Gajewski

Microcytosis is observed in healthy Japanese breed dogs. The aim of the study was to evaluate the frequency and intensity of asymptomatic anisocytosis using a three-grade scale in Japanese dog breeds with special emphasis on the following indices: mean cell volume, mean cell haemoglobin, mean cell haemoglobin concentration, and red blood cell distribution width. The retrospective study included analyses of blood morphology and blood smear for clinically healthy Japanese dog breeds Shiba, Akita, and Hokkaido aged from 6 months to 14 years, performed as a part of preventative care. A total of 74 dogs of both sexes were qualified for the study. The group included both neutered and non-neutered animals (Akita – 17 females, 12 males, Shiba – 24 females, 18 males, Hokkaido – 2 females, 1 male). The blood smear revealed significant anisocytosis in 60.8% and mild anisocytosis in 28.4% of the tested dogs – 89.2% in total. Microcytosis was reported for 25.7% of the tested Japanese breed dogs. Reduced mean cell haemoglobin and mean cell haemoglobin concentration were diagnosed in 75.7% and 40.5% of dogs, respectively. Red blood cell distribution width as an anisocytosis indicator exceeded the norm in 12% of the tested dogs. Compared to mixed breed dogs, the Japanese breeds had a reduced mean cell volume, mean cell haemoglobin concentration and significant anisocytosis in the blood smear as well as a higher red blood cell distribution width indicator. Veterinarians should consider these differences when interpreting the results of morphological blood tests.


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