Changes in Psychological Symptoms after Treatment with a Novel Therapy, the Phoenix Protocol: A Case Series

2018 ◽  
Vol 10 (2) ◽  
pp. 50-59
Author(s):  
Ron E. Masters ◽  
Kara K. Baertsch ◽  
Jessica M. Troxel
Keyword(s):  
Psychological Symptoms ◽  
Case Series ◽  
Novel Therapy ◽  
The Phoenix

Autotransfusion of vaginally shed blood as a novel therapy in obstetric hemorrhage: A case series

Transfusion ◽  
2022 ◽  
Author(s):  
Jaclyn M. Phillips ◽  
Takahiro Tamura ◽  
Jonathan H. Waters ◽  
Jacob Larkin ◽  
Sara Sakamoto
Keyword(s):  
Case Series ◽  
Obstetric Hemorrhage ◽  
Novel Therapy ◽  
Shed Blood

Exposure, Relaxation, and Rescripting Therapy for Trauma-Related Nightmares With Psychiatric Inpatients: A Case Series

2020 ◽  
Vol 20 (1) ◽  
pp. 3-21
Author(s):  
Helen Reiter ◽  
Leanne Humphreys
Keyword(s):  
Acute Care ◽  
Psychiatric Hospital ◽  
Psychological Symptoms ◽  
Psychiatric Patients ◽  
Hospital Setting ◽  
Case Series ◽  
Psychiatric Inpatients ◽  
Empirically Supported ◽  
Individualized Care

Research has shown that posttraumatic stress disorder (PTSD) is a highly prevalent diagnosis for psychiatric patients, yet individualized care and treatment is limited in the inpatient acute care sector. Two case studies are presented which examine the use of Exposure, Relaxation, and Rescripting Therapy (ERRT) for chronic trauma-related nightmares, within a private acute care inpatient psychiatric hospital setting. ERRT is empirically supported with efficacy for veteran and civilian populations, however no research to date has been conducted with psychiatric inpatients. Two participants diagnosed with PTSD, suffering distressing trauma-related nightmares, completed ERRT over three sessions during their psychiatric hospital admission, with the aim of reducing the frequency and severity of nightmares and related psychological symptoms. PTSD, depression, sleep quality and quantity, and nightmare frequency and related distress, were measured pre-treatment, during treatment, and follow-up at one, 3 and 6 months. Only one participant reported ongoing nightmares by the third week of the intervention, with both participants reporting an absence of nightmares at the one and 3-month follow-ups, but mixed results by the 6-month follow-up. One participant also reported a reduction in PTSD symptoms and a mild improvement in depression. The results offer some preliminary support for the provision of ERRT for the treatment of trauma-related nightmares for psychiatric inpatients.

scholarly journals Spontaneous spondylodiscitis and endocarditis: interdisciplinary experience from a tertiary institutional case series and proposal of a treatment algorithm

2021 ◽  
Author(s):  
Lennart Viezens ◽  
Marc Dreimann ◽  
André Strahl ◽  
Annika Heuer ◽  
Leon-Gordian Koepke ◽  
...  
Keyword(s):  
Treatment Algorithm ◽  
Case Series ◽  
Improve Patient Care ◽  
Transoesophageal Echocardiography ◽  
Simultaneous Presence ◽  
Novel Therapy ◽  
Therapy Algorithm ◽  
Efficient Treatment ◽  
Treatment Processes ◽  
Delays In Diagnosis

AbstractPreviously, the simultaneous presence of endocarditis (IE) has been reported in 3–30% of spondylodiscitis cases. The specific implications on therapy and outcome of a simultaneous presence of both diseases are not yet fully evaluated. Therefore, the aim of this study was to investigate the influence of a simultaneously present endocarditis on the course of therapy and outcome of spondylodiscitis. A prospective database analysis of 328 patients diagnosed with spontaneous spondylodiscitis (S) using statistical analysis with propensity score matching was conducted. Thirty-six patients (11.0%) were diagnosed with concurrent endocarditis (SIE) by means of transoesophageal echocardiography. In our cohort, the average age was 65.82 ± 4.12 years and 64.9% of patients were male. The incidence of prior cardiac or renal disease was significantly higher in the SIE group (coronary heart disease SIE n = 13/36 vs. S n = 57/292, p < 0.05 and chronic heart failure n = 11/36 vs. S n = 41/292, p < 0.05, chronic renal failure SIE n = 14/36 vs. S n = 55/292, p < 0.05). Complex interdisciplinary coordination and diagnostics lead to a significant delay in surgical intervention (S = 4.5 ± 4.5 days vs. SIE = 8.9 ± 9.5 days, p < 0.05). Mortality did not show statistically significant differences: S (13.4%) and SIE (19.1%). Time to diagnosis and treatment is a key to efficient treatment and patient safety. In order to counteract delayed therapy, we developed a novel therapy algorithm based on the analysis of treatment processes of the SIE group. We propose a clear therapy pathway to avoid frequently observed pitfalls and delays in diagnosis to improve patient care and outcome.

Dupilumab as a novel therapy for bullous pemphigoid: A multicenter case series

2020 ◽  
Vol 83 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Rana Abdat ◽  
Reid A. Waldman ◽  
Valeria de Bedout ◽  
Annette Czernik ◽  
Michael Mcleod ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Case Series ◽  
Novel Therapy

Gastric peroral endoscopic myotomy for the treatment of refractory gastroparesis: a multicenter international experience

Endoscopy ◽  
2018 ◽  
Author(s):  
Michel Kahaleh ◽  
Jean-Michel Gonzalez ◽  
Ming-ming Xu ◽  
Iman Andalib ◽  
Monica Gaidhane ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Hospital Stay ◽  
Case Series ◽  
Length Of Hospital Stay ◽  
Novel Therapy ◽  
Gastric Emptying Scintigraphy ◽  
Post Procedure ◽  
The Mean ◽  
Procedure Duration

Abstract Background Gastroparesis is a difficult-to-treat motility disorder with a poor response to medical therapy. Gastric peroral endoscopic pyloromyotomy (G-POEM) has been offered as a novel therapy in the treatment of refractory gastroparesis. We present a multicenter case series of our experience with G-POEM. Methods This is an international multicenter case series of patients who underwent G-POEM for the treatment of gastroparesis. The severity of gastroparesis was assessed by delayed gastric emptying scintigraphy (GES) and an elevated gastroparesis cardinal symptoms index (GCSI). Patients then underwent G-POEM using the submucosal tunneling technique. The primary endpoint was improvement in the GCSI score and improvement in gastric emptying on repeat scintigraphy. Secondary endpoints were technical success, complication rate, procedure duration, and length of hospital stay post-procedure. Results G-POEM was technically successful in all 33 patients. Symptomatic improvement was seen in 28/33 patients (85 %), with a decrease in symptom score by GCSI from 3.3 to 0.8 at follow-up (P < 0.001). The mean procedure duration was 77.6 minutes (37 – 255 minutes). Mean GES improved significantly from 222.4 minutes to 143.16 minutes (P < 0.001). Complications were minimal and included bleeding (n = 1) and an ulcer (n = 1) treated conservatively. The mean length of hospital stay post-procedure was 5.4 days (1 – 14 days). The mean follow-up duration was 11.5 months (2 – 31 months). Conclusion G-POEM is a technically feasible, safe, and successful procedure for the treatment of refractory gastroparesis. A further multicenter comparative study should be performed to compare this technique to laparoscopic pyloromyotomy.

scholarly journals LOOP ILEOSTOMY

2011 ◽  
Vol 18 (02) ◽  
pp. 222-227
Author(s):  
MUHAMMAD SHER-UZ-ZAMAN ◽  
FAWAD HAMEED ◽  
SHEIKH ATIQ-UR-REHMAN ◽  
Younis Khan
Keyword(s):  
Typhoid Fever ◽  
Psychological Symptoms ◽  
Loop Ileostomy ◽  
Case Series ◽  
Female Ratio ◽  
Life Saving ◽  
Surgical Units ◽  
Case Series Study ◽  
Enteric Perforation ◽  
Considerable Morbidity

Enteric perforation is a disastrous complication of untreated or poorly treated typhoid fever and unless treated by surgical method, it results in considerable morbidity and mortality. The purpose of this study to describe complications of ileostomy in patients of enteric perforation. Place & Duration of study: The study was conducted was in surgical units B-V hospital, Bahawalpur from 1st July 2008 to 30th June 2009. Material & Method: This was a descriptive case series study. 100 patients of both genders suffering from typhoid fever with perforation who underwent ileostomy were included the study. All the data was collected on pre-designed proforma. Results: Most of the patients were young with male to female ratio 1.6:1. Ileostomy was done in all the patients after cleaning the peritoneal cavity. Ileostomy was associated with diarrhea 20%, peristomal skin problems 22%. Other complications were bleeding in 3%,prolapsed in 5%, retraction in 4%, parastomal hernia in 5%, wound infection in 8%, intestinal obstruction in 5% patients, incisional hernia & psychological symptoms in 2% patients and stoma stenosis in one patient in our study. Two patients expired due the complication of ileostomy. Conclusions: Although ileostomy is not the most favored way of treatment of enteric perforation and it is associated with a number of complications and management problems, it is still a good option and life saving procedure in our setup where patients present very late with gross peritoneal contamination. 

scholarly journals Virtual Reality Experience In Long Term Care Resident Older Adults With Dementia: A Case Series 

2020 ◽  
Author(s):  
Munira Sultana ◽  
Karen Campbell ◽  
Morgan Jennings ◽  
Manuel Montero-Odasso ◽  
Joseph. B. Orange ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Long Term Care ◽  
Psychological Symptoms ◽  
Care Home ◽  
Case Series ◽  
Recruitment Rate ◽  
Adherence Rate ◽  
Term Care ◽  
Convenience Sample

Abstract BACKGROUND: Behavioural and Psychological Symptoms of Dementia (BPSD) worsens as dementia progresses, intensifies caregiver distress and consequent institutionalization. We wanted to evaluate feasibility of Virtual Reality (VR) as non-pharmacologic intervention for BPSD in a long-term care home. METHODS: A single site (Henley Place at London, Ontario) case series with a convenience sample (24 older adult residents with moderate to severe dementia). Intervention was 30 minutes of VR experience with Broomx©, five days a week for two weeks. RESULTS: Implementing VR experience was possible at Henley Place (recruitment rate=40%, the adherence rate=21%, and the attrition=0%) and participants could tolerate it. No adverse events and one-to-one staff use were recorded during the intervention period. CONCLUSION: VR experience can be implemented in a care home. TRIAL REGISTRATION: The study was not registered as clinical trial. We obtained ethics approval from ADVARRA Canada Ethics Board before recruiting participants for the study.

A systematic review of the association between the Behavioral and Psychological Symptoms of Dementia and burden of care

2004 ◽  
Vol 16 (3) ◽  
pp. 295-315 ◽  
Author(s):  
Warwick Black ◽  
Osvaldo P. Almeida
Keyword(s):  
Systematic Review ◽  
Psychological Distress ◽  
Longitudinal Data ◽  
Psychological Symptoms ◽  
Case Series ◽  
Burden Of Care ◽  
Cross Sectional ◽  
Caregiver Depression ◽  
The Relationship ◽  
Behavioral And Psychological Symptoms

Background: Several reports have indicated that the Behavioral and Psychological Symptoms of Dementia (BPSD) are associated with increased burden of care, carer depression and increased rates of institutionalization of patients. The present study aims to review the association between these variables in cross-sectional as well as longitudinal studies.Methods: Systematic review and meta-analysis of all available information published in English between January 1990 and December 2001 was made. Case-reports, case-series and studies with 20 or fewer subjects were excluded from the analyses.Results: Thirty articles are included in the review of cross-sectional data and 12 in the systematic review of longitudinal data. Pooled correlation coefficients were generated for the relationship between BPSD and caregiver burden (rpooled=0.57; 95% CI=0.52 to 0.62), caregiver psychological distress (rpooled=0.41; 95% CI=0.32 to 0.49) and caregiver depression (rpooled=0.30; 95% CI=0.21 to 0.39), suggesting that these concepts have a moderately strong association. Multivariate data, on the whole, further supported the notion that BPSD are a predictor of burden of care and of psychological distress and depression. Limited longitudinal data made clarifying the temporal relationahip between BPSD and the psychological sequelae of care (PSC) difficult. The limited data pertaining to the relationship between BPSD and institutionalization suggest that caregiver variables may be more important in predicting institutionalization than BPSD. Methodological issues and limitations associated with this type of investigation were also considered.Conclusion: The results of this review support, but do not conclusively establish, the association between BPSD and PSC. We propose that the concept of burden of care be abandoned in favor of more clinically relevant outcomes such as caregiver depression.

scholarly journals Changes in Psychological Symptoms and Heart Rate Variability During EMDR Treatment: A Case Series of Subthreshold PTSD

2010 ◽  
Vol 4 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Alessandra Frustaci ◽  
Gaetano A. Lanza ◽  
Isabel Fernandez ◽  
Massimo di Giannantonio ◽  
Gino Pozzi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Psychological Symptoms ◽  
Trauma Exposure ◽  
Case Series ◽  
Self Report ◽  
Holter Ecg ◽  
End Of Treatment ◽  
Report Symptom

Elevated psychophysiological parameters and heightened physiological reactivity to trauma-related cues are acquired changes following trauma exposure. Measuring improvement in these variables is an appropriate evaluation of outcome in treatment studies. Heart Rate Variability (HRV) is a computerized measure of physiological responsivity derived from Holter ECG recording. Four female outpatients with persistent post-traumatic symptoms and personal impairment following “small t” trauma exposure underwent a course of EMDR treatment and were assessed at baseline, end of treatment, day 30 and day 90 of follow-up, using self-report symptom scales and 90-min Holter ECG recordings. Symptom scores decreased between baseline and end of treatment, with improvement maintained at follow-up. Several HRV measures changed favorably in different recording intervals. HRV is a feasible and sensitive method to measure physiological changes in the treatment of individuals distressed by “small t” trauma. Further investigation is advisable to expand these preliminary data.

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