Favorable pregnancy outcomes following continual intramuscular lorazepam use in late pregnancy

2013 ◽  
Vol 3 (2) ◽  
pp. 96-98
Author(s):  
Karen E. Moeller
Keyword(s):  
Case Report ◽  
Pregnancy Outcomes ◽  
Late Pregnancy ◽  
Pregnant Patient ◽  
High Dose ◽  
Third Trimester ◽  
The Third

Use of benzodiazepines during pregnancy is controversial due to conflicting studies in the literature. Furthermore, few published reports on continual use of parenteral benzodiazepines during the third trimester of pregnancy have been published. This case report evaluates the use of high-dose intramuscular lorazepam in a pregnant patient during her last three weeks of gestation.

Glycated Albumin in Pregnancy: Reference Intervals Establishment and Its Predictive Value in Adverse Pregnant Outcomes

2019 ◽  
Author(s):  
Ying Dong ◽  
Yanhong Zhai ◽  
Jing Wang ◽  
Xin Xie ◽  
Chunhong Zhang ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Predictive Value ◽  
Glycated Albumin ◽  
Late Pregnancy ◽  
Reference Intervals ◽  
Diabetic Patients ◽  
Third Trimester ◽  
The Third ◽  
Adverse Pregnancy ◽  
In Pregnancy

Abstract Background As one of the most common pregnant complications, the gestational diabetes mellitus (GDM) is associated with significant adverse pregnant outcomes and it is crucial to accurately monitor the glycemic states of GDM patients. The HbA1c which is a traditional long-term glycemic marker used in diabetic patients, is not recommended in GDM patients during pregnancy. Recently, many efforts have been focused on the alternative marker glycated albumin (GA) and its application in pregnancy during which profound physiological changes take place. Our objective was to determine the reference intervals (RIs) of GA in healthy Chinese pregnant women and to assess the predictive value of serum GA in adverse pregnant outcomes. Methods Totally 479 healthy subjects including 153 in the first trimester, 174 in the second trimester, and 152 in the third trimester were enrolled from March to July 2019, for the purpose of establishing the trimester-specific RIs of GA. The diagnostic value of GA for GDM patients was evaluated and compared with that of fasting plasma glucose (FPG) at 24-28 weeks of gestation. The association between GA in the late pregnancy and the adverse pregnant outcomes was analyzed retrospectively with the data collected from January to June 2018 at our hospital. Results The estimated RIs of GA in present study were 10.87-15.09 %, 10.04-13.50 %, and 9.78-13.03 % in the first, second, and third trimesters respectively. The areas under receiver operating characteristic (ROC) curves were 0.503 for GA and 0.705 for FPG. More importantly, the GA levels of the third trimester did not show significant changes in women with large-for-date birth weight, preterm delivery, postpartum hemorrhage or hypertension when compared in women with normal pregnancy outcomes. The exception was that the GDM patients who developed preeclampsia did have a lower GA level in their late pregnancy. Conclusions Our results show that the GA was continuously decreased as the gestational age went up. It has limited value in diagnosing GDM and predicting adverse pregnancy outcomes.

Obstetric cholestasis

1997 ◽  
Vol 9 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Nicholas Raine-Fenning ◽  
Mark Kilby
Keyword(s):  
Case Report ◽  
Liver Function ◽  
Maternal Morbidity ◽  
Acute Viral Hepatitis ◽  
Pregnant Patient ◽  
Fetal Outcome ◽  
Third Trimester ◽  
The Third ◽  
First Case ◽  
Characteristic Features

Obstetric cholestasis (OC) is associated with significant perinatal mortality and maternal morbidity. Fetal outcome may be improved with increased antenatal surveillance and timely intervention. Frequently attributed to the Scandinavian authors Alvar Svanborg and Leif Thorling, the first case report was by Ahlfeld in 1883 who elegantly described recurrent jaundice in a pregnant patient that remitted with delivery. During the 1950's various terminologies originated describing some of the characteristic features of the disease: icterus gravidarum, cholestatic hepatosis and recurrent jaundice during pregnancy, all synonymous with ‘obstetric cholestasis.’ Ahlfeld's original patient did not complain of itching but over the recent years pruritis has become the commonest manifestation. Obstetric cholestasis is the most common disorder of liver function unique to pregnancy and second only to acute viral hepatitis as a cause of jaundice in the third trimester.

scholarly journals Sight-Threatening Graves’ Ophthalmopathy during the Third Trimester of Pregnancy: A Case Report

2020 ◽  
Vol 252 (4) ◽  
pp. 321-327
Author(s):  
Kanako Sakurai ◽  
Toshu Inoue ◽  
Satsuki Niitsuma ◽  
Ryota Sato ◽  
Kazuhiro Takahashi ◽  
...  
Keyword(s):  
Case Report ◽  
Third Trimester ◽  
The Third ◽  
Graves Ophthalmopathy

Androgen secretion in women with threatened miscarriage

2020 ◽  
Vol 19 (5) ◽  
pp. 22-28
Author(s):  
М.М. Amiraslanova ◽  
◽  
I.V. Kuznetsova ◽  
E.P. Gitel ◽  
◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
First Trimester ◽  
Total Testosterone ◽  
Third Trimester ◽  
Group Iii ◽  
The Third ◽  
Threatened Miscarriage ◽  
Group I ◽  
Androgen Secretion ◽  
Group Ii

Objective. To assess androgen secretion and its possible effect on pregnancy in women with threatened miscarriage in the first trimester. Patients and methods. This prospective observational study included 120 pregnant women divided into four groups. Group I comprised 32 patients with threatened miscarriage and hyperandrogenism who received corticosteroids; Group II was composed of 28 patients with threatened miscarriage and hyperandrogenism who did not receive corticosteroids; Group III included 30 patients with threatened miscarriage and no hyperandrogenism; and Group IV comprised 30 women with normal pregnancy. Serum levels of dehydroepiandrosterone sulfate (DHEA-S), 17-hydroxyprogesterone (17-OHP), and total testosterone were measured on the following weeks of gestation: 5–8, 9–12, 13–18, 19–24, and 25–32. We also evaluated clinical outcomes of pregnancy. Results. We observed no significant differences in 17-ОНР and DHEA-S secretion between women from Group III and controls. Patients from Group II demonstrated higher hormone levels than controls; however, their dynamics of 17-ОНР and testosterone secretion was similar to that in women without hyperandrogenism, so their DHEA-S levels decreased and reached control values by the third trimester. Corticosteroids reduced 17-ONR secretion in the second and third trimesters and DHEA-S secretion in the third trimester. Women receiving corticosteroids demonstrated the poorest clinical pregnancy outcomes. Conclusion. Hyperandrogenism should be considered as one of the risk factors for poor pregnancy outcomes. Administration of corticosteroids to reduce androgen levels impairs normal dynamics of their secretion, does not improve pregnancy outcomes, and is potentially harmful; therefore, these drugs should not be used for such purposes. Key words: pregnancy, hyperandrogenism, corticosteroid therapy, pregnancy outcomes, pregnancy loss, androgen secretion, threatened miscarriage

scholarly journals Juvenile granulosa cell tumour in the third trimester of pregnancy

2020 ◽  
Vol 9 (2) ◽  
pp. 861
Author(s):  
Jonathan Gaughran ◽  
Argha Datta ◽  
Judith Hamilton ◽  
Tom Holland ◽  
Ahmad Sayasneh
Keyword(s):  
Case Report ◽  
Granulosa Cell ◽  
Cell Tumour ◽  
Granulosa Cell Tumour ◽  
Third Trimester ◽  
Rare Finding ◽  
Histopathological Findings ◽  
The Third ◽  
In Pregnancy

This case report describes the rare finding of a granulosa cell tumour in the third trimester of pregnancy. The presentation, investigation, management, histopathological findings and subsequent follow up are detailed. The difficulties associated with such diagnoses in pregnancy are explored.

scholarly journals Uterine torsion of 90 degrees: case report

2020 ◽  
Vol 9 (4) ◽  
pp. 1743
Author(s):  
S. Tanouti ◽  
M. Chakri ◽  
H. Taheri ◽  
H. Saadi ◽  
A. Mimouni
Keyword(s):  
Case Report ◽  
Caesarean Section ◽  
Emergency Caesarean Section ◽  
Third Trimester ◽  
Singleton Pregnancy ◽  
The Third ◽  
Emergency Caesarean ◽  
Uterine Torsion ◽  
Vaginal Deliveries ◽  
Obstetrical Unit

Uterine torsion is defined as a rotation of uterus more than 45 degrees along its long axis. However, a pathologic rotation of the uterus beyond 45 degrees-torsion of the entire uterus-is rarely seen in obstetrical practice, authors report a case of torsion of the uterus by 90 degrees. The patient, a 30-year-old gravida 3 para 2 at 37 weeks’ gestation with a singleton pregnancy, her prior obstetrical history included two uncomplicated term vaginal deliveries, and the current pregnancy had been uncomplicated until the date of presentation was admitted to the obstetrical unit  with  labour at 37 weeks 5 days ,on obstetric examination the patient was in labour with transversal presentation of the fetus so an emergency caesarean section (CS) was carried out for. At the time of CS, the diagnosis of uterine torsion of 90 degrees was made. After the delivery of the baby, uterus returned to anatomical position and the torsion corrected spontaneously. The patient recovered and was discharged home with her baby on the third postoperative day. Uterine torsion is an infrequently reported and potentially dangerous complication of pregnancy that occurs mainly in the third trimester.

Successful Use of Argatroban During the Third Trimester of Pregnancy: Case Report and Review of the Literature

2008 ◽  
Vol 28 (12) ◽  
pp. 1531-1536 ◽  
Author(s):  
Sallie K Young ◽  
Hamid A Al-Mondhiry ◽  
Sonia J Vaida ◽  
Anthony Ambrose ◽  
John J Botti
Keyword(s):  
Case Report ◽  
Review Of The Literature ◽  
Third Trimester ◽  
The Third
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