Results of Factor V Leiden Mutation Screening in Patients with Deep Vein Thrombosis

2013 ◽  
Vol 22 (1) ◽  
pp. 110-116 ◽  
Author(s):  
Olcay Murat DİŞLİ ◽  
Barış AKÇA ◽  
Köksal DÖNMEZ ◽  
Cengiz ÇOLAK ◽  
Hasan Berat CİHAN ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Mutation Screening ◽  
Factor V Leiden ◽  
Factor V ◽  
Factor V Leiden Mutation ◽  
Vein Thrombosis ◽  
Deep Vein

Deep Vein Thrombosis during Varicella in a Child with Factor V Leiden Mutation and Familial Deficiency of Protein S

2001 ◽  
Vol 85 (02) ◽  
pp. 370-370
Author(s):  
Luca Masotti ◽  
Giacomo Zanelli ◽  
Stefania Battistini ◽  
Sandro Forconi ◽  
Roberto Cappelli
Keyword(s):  
Deep Vein Thrombosis ◽  
Factor V Leiden ◽  
Protein S ◽  
Factor V ◽  
Factor V Leiden Mutation ◽  
Vein Thrombosis ◽  
Deep Vein

Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen

The Lancet ◽  
1995 ◽  
Vol 346 (8990) ◽  
pp. 1593-1596 ◽  
Author(s):  
K.W.M. Bloemenkamp ◽  
F.M. Helmerhorst ◽  
F.R. Rosendaal ◽  
J.P. Vandenbroucke ◽  
H.R. Büller
Keyword(s):  
Deep Vein Thrombosis ◽  
Oral Contraceptives ◽  
Factor V Leiden ◽  
Factor V ◽  
Third Generation ◽  
Factor V Leiden Mutation ◽  
Vein Thrombosis ◽  
Deep Vein

scholarly journals Risk Factor Profiles in Patients with Different Clinical Manifestations of Venous Thromboembolism: A Focus on the Factor V Leiden Mutation

1996 ◽  
Vol 76 (04) ◽  
pp. 510-513 ◽  
Author(s):  
Bert Manten ◽  
Rudi G J Westendorp ◽  
Ted Koster ◽  
Pieter H Reitsma ◽  
Frits R Rosendaal
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Venous Thromboembolism ◽  
Clinical Manifestations ◽  
Factor V Leiden ◽  
Factor V ◽  
Factor V Leiden Mutation ◽  
Vein Thrombosis ◽  
Increased Risk ◽  
Deep Vein

Summary Background. Patients with venous thromboembolic disease may present with different clinical manifestations. Factor V Leiden mutation leading to resistance to activated protein C is associated with a sevenfold increased risk for presenting with deep-vein thrombosis. It is not yet established whether carriers of the mutation have a similarly increased risk for manifesting with pulmonary embolism. Methods. From an Anticoagulation Clinic monitoring coumarin therapy, a consecutive series of patients with a first thromboembolic event (objectively proven by current radiological methods) were enrolled. All patients were interviewed and blood was drawn for geno-typing. From the hospital charts and the personal interview, information was obtained on acquired risk factors and the signs and symptoms on hospital admission. Results. 45 patients presented with symptoms of pulmonary embolism only, 211 had only symptoms of deep-vein thrombosis whereas 23 had clinical features of both. In about half of the patients acquired risk factors for venous thromboembolism were present which did not differ between the three groups of patients. Recent surgery had been performed more often in patients presenting with pulmonary embolism than in other patients (33.3% vs. 18.5%, p <0,05). Factor V Leiden was present in 9% of the patients presenting with pulmonary embolism (relative risk: 3.3 95% Cl: 1.0-10.6) and 17% of the patients presenting with deep-vein thrombosis (relative risk: 6.9 95% Cl: 3.6-12.8). The prevalence of factor V Leiden was intermediate in patients with both clinical characteristics. Conclusion. These data suggest that patients with venous thromboembolism have different clinical presentation depending on the risk factor profile. Factor V Leiden may preferentially lead to manifest deep-vein thrombosis. Differences in structure of venous thrombi could underlie differences in embolic tendency.

Factor V Leiden mutation in Egyptian patients with deep vein thrombosis

2016 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
MonaH.A. Yaman ◽  
MohamedM Elwageh ◽  
AmiraY Abd-Elnaby ◽  
ManalA.W. Eid
Keyword(s):  
Deep Vein Thrombosis ◽  
Factor V Leiden ◽  
Factor V ◽  
Factor V Leiden Mutation ◽  
Vein Thrombosis ◽  
Egyptian Patients ◽  
Deep Vein

Factor V Leiden Mutation in Patients with Breast Cancer with a Central Venous Catheter: Risk of Deep Vein Thrombosis

2006 ◽  
Vol 3 (2) ◽  
pp. 98-102 ◽  
Author(s):  
Giuseppe Curigliano ◽  
Mario Mandalà ◽  
Alberto Sbanotto ◽  
Marco Colleoni ◽  
Gianluigi Ferretti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Deep Vein Thrombosis ◽  
Central Venous Catheter ◽  
Factor V Leiden ◽  
Venous Catheter ◽  
Factor V ◽  
Central Venous ◽  
Factor V Leiden Mutation ◽  
Vein Thrombosis ◽  
Deep Vein
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