scholarly journals SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SCHIFFS BASES

2014 ◽  
Vol 3 (1) ◽  
pp. 10-13
Author(s):  
Omran Fhid ◽  
Talal Zeglam ◽  
Asma Gebril
Keyword(s):  
Biological Evaluation ◽  
Schiffs Bases

scholarly journals Synthesis, characterization and biological evaluation of Schiff’s bases derivatives as potent antibacterial agents

2017 ◽  
Vol 4 (5) ◽  
pp. 216
Author(s):  
Versha Parcha ◽  
Ankit Kumar ◽  
Babita Mahajan ◽  
Jaswinder Kaur
Keyword(s):  
Antibacterial Effect ◽  
Biological Evaluation ◽  
Spectral Studies ◽  
Schiff’S Bases ◽  
Zone Of Inhibition ◽  
Schiff's Bases ◽  
Almost All ◽  
Derivatives Of ◽  
Antibacterial Potential ◽  
Schiffs Bases

Objective: To design, synthesize and screen biologically newer Substituted Schiff bases by condensing substituted acid hydrazides with various benzaldehydes and explore their antimicrobial potential.Methods: Present study synthesis of various derivatives of Schiffs bases was carried out by: firstly converting substituted acids to acid hydrazides and then to Schiff's bases after condensation with substituted benzaldehyde. Synthesized compounds were characterised on the basis of spectral studies (like UV, IR, and NMR). All the synthesized derivatives were screened further for their antibacterial effect against Salmonella typhimurium, Shigella sonnei, Staphylococcus aureus& Bacillus cereus.Results: From this study it could be observed that schiff’s bases 2-[( aminophenylhydrazinyldene o,m,dinitrobenzoyl] aniline (H) and compound 2-[( aminophenylzinyldene) p amino benzoyl] aniline (I) showed very good zone of inhibition against almost all strains tested for.Conclusions: So further attempts could be made to extend the series and explore their antibacterial potential to achieve hopeful goal.

Chemical and biological evaluation of native bamboo species from atlantic rain forest

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
MT Grombone-Guaratini ◽  
LM Brandão Torres ◽  
DA Faria ◽  
CM José
Keyword(s):  
Rain Forest ◽  
Biological Evaluation ◽  
Atlantic Rain Forest ◽  
Bamboo Species

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF 3-FORMYL INDOLE BASED SCHIFF BASES

2018 ◽  
Vol 7 (6) ◽  
Author(s):  
Singh Gurvinder ◽  
Singh Prabhsimran ◽  
Dhawan R. K.
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Analysis ◽  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Biological Evaluation ◽  
Fungal Strain ◽  
Bacterial Strains ◽  
Standard Drug ◽  
Gram Negative ◽  
E Coli

In order to develop new antimicrobial agents, a series of 3-formyl indole based Schiff bases were synthesized by reacting 3-formyl indole(indole-3-carboxaldehyde) with substituted aniline taking ethanol as solvent. The reaction was carried in the presence of small amount of p-toluene sulphonic acid as catalyst.All the synthesized compounds were characterized by IR, 1H-NMR spectral analysis. All the synthesized compounds were evaluated for antimicrobial activity against two gram positive bacterial strains (B. subtilisand S. aureus) and two gram negative bacterial strains (P. aeruginosaand E. coli) and one fungal strain (C. albicans). All the synthesized compounds were found to have moderate to good antimicrobial activity. The  standard drug amoxicillin, fluconazole were used for antimicrobial activity. Among the synthesized compounds, the maximum antimicrobial activity was shown by compounds GS04, GS07, GS08 and GS10.

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