scholarly journals QUANTITATIVE PHYTOCHEMICAL AND GC-MS ANALYSIS OF LEAF AND BARK EXTRACT OF DOLICHANDRONE ATROVIRENS

2015 ◽  
Vol 6 (3) ◽  
pp. 219-222
Author(s):  
Saminathan Kayarohanam ◽  
Kavimani S
2019 ◽  
Vol 8 (4) ◽  
pp. 177-184
Author(s):  
Sivaraj C ◽  
◽  
Saraswathi K ◽  
Arumugam P ◽  
Baskar R ◽  
...  

Author(s):  
Aruna L. Hugar ◽  
Amarvani P. Kanjikar ◽  
Ramesh L. Londonkar

Introduction: Medicinal plants still represent untapped sources of novel compounds with potential therapeutic effects for mitigating human maladies.Pterocarpus marsupium, commonly known as Bijasal, is a well-known drug in ayurvedic system of medicine. Materials and methods: The dried bark powder of P.marsupium was extracted by Soxhlet with methanol and analyzed by gas chromatography, while the mass spectra data of the compounds found in the extract was matched with the data available at National Institute of Standards and Technology (NIST) library. Results: The results of the GC-MS analysis provide different peaksdetermining the presence of 10 major phytocomponents, that are 1-Penten-3-one,1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-; Geranyl isovalerate; 2-Pentadecanone,6, 10, 14-trimethyl;Cyclopropaneoctanal, 2-octyl-; Octadecanoic acid;10-Octadecanoic acid, methyl ester; Heptadecanoic acid, 16-methyl,-methyl ester; Phytol; 4,8,12,16-Tetramethyl heptadecan-4-olide; Dasycarpidan-1-methanol, acetate with different therapeutic activities. Conclusion: The presence of these bioactive compounds justifies that the Pterocarpus marsupiumcan offer a base for using this compound as herbal alternative for the synthesis and development of new drug to treat various infectious diseases. However, isolation of individual phytochemical constituents might be useful to formulate a new novel drug.


2017 ◽  
Vol 3 (08) ◽  
pp. 34-45 ◽  
Author(s):  
Olufunmiso O. Olajuyigbe ◽  
Faith O Ijeyan ◽  
Morenike O. Adeoye-Isijola

Author(s):  
Hamisu Ibrahim ◽  
Ahmed Jibrin Uttu ◽  
Muhammad Sani Sallau ◽  
Ogunkemi Risikat Agbeke Iyun

Abstract Background Majority of phytochemicals have been known to bear valuable therapeutic activities such as insecticidal, antibacterial, antifungal, anticonstipative, spasmolytic, antiplasmodial and antioxidant activities. Strychnos innocua is straight-stemmed tree belonging to the family Loganiaceae and can grow up to 18 m tall. The plant is used for various pharmacological purposes. The aim of this study was to determine the chemical composition of the ethyl acetate extract of root bark of S. innocua using GC–MS analysis. The root bark was collected, air-dried and then crushed to powder. Standard extraction method (maceration) was used to obtain the ethyl acetate extract. The GC–MS was carried out on the extract using GC 7890B, MSD 5977A, Agilent Tech. Results Thirty-seven compounds were identified among which dibutyl benzene-1,2-dicarboxylate showed the highest peak area (31.03%) and monomethyl pimelate showed the lowest peak area (0.39%). The major compounds identified were cyclooctane (methoxymethoxy), 2,4-dimethylheptanedioic acid dimethyl ester, azelaic acid, 1,2-benzenedicarboxylic acid, bis(2-methylpropyl) ester, dibutyl benzene-1,2-dicarboxylate, butyl 8-methylnonyl benzene-1,2-dicarboxylate, 9,15-octadecadienoic acid, methyl ester, cis-vaccenic acid, linoleic acid ethyl ester and ethyl oleate. Conclusions In conclusion, these phytoconstituents might be responsible for the medicinal efficacy of the root bark of S. innocua and can be used as a source therapeutic drug.


Foods ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 420 ◽  
Author(s):  
Xiaopu Ren ◽  
Wei Wang ◽  
Yingjie Bao ◽  
Yuxia Zhu ◽  
Yawei Zhang ◽  
...  

Tamarix has been widely used as barbecue skewers to obtain a good taste and a unique flavor of roast lamb in China. Many flavonoids have been identified from Tamarix, which is an important strategy employed to reduce the formation of heterocyclic amines (HAs) in roast meat. Isorhamnetin, hispidulin, and cirsimaritin from Tamarix ramosissima bark extract (TRE) effectively inhibit the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP), the most abundant HAs in foods, both in roast lamb patties and in chemical models. According to the results of the GC-MS analysis, TRE and the three flavonoids significantly reduced the contents of phenylacetaldehyde, an important intermediate involved in PhIP formation at three levels. A subsequent ultra performance liquid chromatography-mass spectrometry (UPLC-MS) analysis revealed that these flavonoids trapped phenylacetaldehyde by forming interaction adducts. The formation of three postulated adducts, 8-C-(E-phenylethenyl)isorhamnetin, 6-C-(E-phenylethenyl)isorhamnetin and 8-C-(E-phenylethenyl)hispidulin, in the chemical models and roast lamb patties was further confirmed by a TOF-MS/MS analysis. Our results demonstrate that TRE and the corresponding flavonoids trap phenylacetaldehyde to form adducts and thus inhibit PhIP formation, suggesting their great potential beneficial effects on human health.


2003 ◽  
Vol 14 (1) ◽  
pp. 54-59 ◽  
Author(s):  
William N. Setzer ◽  
Bernhard Vogler ◽  
Robert B. Bates ◽  
Jennifer M. Schmidt ◽  
Christopher W. Dicus ◽  
...  
Keyword(s):  

2011 ◽  
Vol 49 (05) ◽  
Author(s):  
S Szabó ◽  
L Márk ◽  
S Kiss ◽  
É Polyák ◽  
A Kisbenedek ◽  
...  
Keyword(s):  

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