scholarly journals Early Results of Gamma Knife Radiosurgery of Acoustic Neurinomas : An Evaluation of Forty-four Cases

1994 ◽  
Vol 3 (3) ◽  
pp. 196-200 ◽  
Author(s):  
Takayuki Tanaka ◽  
Tatsuya Kobayashi ◽  
Yoshihisa Kida ◽  
Hirofumi Oyama ◽  
Takayasu Iwakoshi ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Early Results ◽  
Acoustic Neurinomas

Gamma Knife radiosurgery for skull base meningioma: long-term results of low-dose treatment

2008 ◽  
Vol 109 (5) ◽  
pp. 804-810 ◽  
Author(s):  
Yoshiyasu Iwai ◽  
Kazuhiro Yamanaka ◽  
Hidetoshi Ikeda
Keyword(s):  
Malignant Transformation ◽  
Gamma Knife ◽  
Low Dose ◽  
Gamma Knife Radiosurgery ◽  
Cranial Base ◽  
Local Failure ◽  
Long Term Results ◽  
Early Results

Object In this study, the authors evaluate the long-term results after Gamma Knife radiosurgery of cranial base meningiomas. This study is a follow-up to their previously published report on the early results. Methods Between January 1994 and December 2001, the authors treated benign cranial base meningiomas in 108 patients using low-dose Gamma Knife radiosurgery. The tumor volumes ranged from 1.7 to 55.3 cm3 (median 8.1 cm3), and the radiosurgery doses ranged from 8 to 12 Gy (median 12 Gy) to the tumor margin. Results The mean duration of follow-up was 86.1 months (range 20–144 months). Tumor volume decreased in 50 patients (46%), remained stable in 51 patients (47%), and increased (local failure) in 7 patients (6%). Eleven patients experienced tumor recurrence outside the treatment field. Among these patients, marginal failure was seen in 5 and distant recurrence was seen in 6. Seven patients were thought to have malignant transformation based on histological or radiological characteristics of the lesion. The actuarial progression-free survival rate, including malignant transformation and outside recurrence, was 93% at 5 years and 83% at 10 years. Neurological status improved in 16 patients (15%). Permanent radiation injury occurred in 7 patients (6%). Conclusions Gamma Knife radiosurgery is a safe and effective treatment for cranial base meningiomas as demonstrated with a long-term follow-up period of > 7 years. Surgeons must be aware of the possibility of treatment failure, defined as local failure, marginal failure, and malignant transformation; however, this may be the natural course of meningiomas and not related to radiosurgery.

Effect of Gamma Knife Radiosurgery on Acoustic Neurinomas

1996 ◽  
Vol 66 (1) ◽  
pp. 93-102 ◽  
Author(s):  
Y. Seo ◽  
S. Fukuoka ◽  
J. Nakagawara ◽  
M. Takanashi ◽  
S. Takahashi ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Acoustic Neurinomas

scholarly journals Gamma Knife Radiosurgery for Acoustic Neurinomas : Part2:The Analysis of Functional Outcome

1997 ◽  
Vol 6 (3) ◽  
pp. 180-185 ◽  
Author(s):  
Seiji Fukuoka ◽  
Masami Takashina ◽  
Yoshinobu Seo ◽  
Shuhei Takahashi ◽  
Jyoji Nakagawara ◽  
...  
Keyword(s):  
Functional Outcome ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Acoustic Neurinomas

Statistical Analysis of Risk Factors after Gamma Knife Radiosurgery of Acoustic Neurinomas

1999 ◽  
pp. 205-213 ◽  
Author(s):  
R. LiSC�k ◽  
J. Novotný Jr. ◽  
D. UrgoSik ◽  
V. Vladyka ◽  
G. Simonov�
Keyword(s):  
Risk Factors ◽  
Statistical Analysis ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Acoustic Neurinomas

Acoustic Neurinomas with Macrocysts Treated with Gamma Knife Radiosurgery

1996 ◽  
Vol 66 (1) ◽  
pp. 103-111 ◽  
Author(s):  
G. Pendl ◽  
J.C. Ganz ◽  
K. Kitz ◽  
S. Eustacchio
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Acoustic Neurinomas

scholarly journals Gamma Knife Radiosurgery for Acoustic Neurinomas : Part1:The Analysis of Tumor Control

1997 ◽  
Vol 6 (2) ◽  
pp. 90-96 ◽  
Author(s):  
Seiji Fukuoka ◽  
Yoshinobu Seo ◽  
Jyoji Nakagawara ◽  
Masami Takashina ◽  
Shuhei Takahashi ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Tumor Control ◽  
Acoustic Neurinomas
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