scholarly journals Evaluation of the In Vivo Efficacy of Novel Monosubstituted Sulfonylureas against H37Rv and Extensively Drug-Resistant Tuberculosis

2014 ◽  
Vol 67 (6) ◽  
pp. 485-487 ◽  
Author(s):  
Yu Liu ◽  
Pengtao Bao ◽  
Di Wang ◽  
Zhengming Li ◽  
Yun Li ◽  
...  
Keyword(s):  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
In Vivo Efficacy ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant

scholarly journals Antitubercular Activity of Disulfiram, an Antialcoholism Drug, against Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Isolates

2012 ◽  
Vol 56 (8) ◽  
pp. 4140-4145 ◽  
Author(s):  
Yasuhiro Horita ◽  
Takemasa Takii ◽  
Tetsuya Yagi ◽  
Kenji Ogawa ◽  
Nagatoshi Fujiwara ◽  
...  
Keyword(s):  
Ex Vivo ◽  
Antitubercular Activity ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Content Type ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant

ABSTRACTThe antimycobacterial activities of disulfiram (DSF) and diethyldithiocarbamate (DDC) against multidrug- and extensively drug-resistant tuberculosis (MDR/XDR-TB) clinical isolates were evaluatedin vitro. Both DSF and DDC exhibited potent antitubercular activities against 42 clinical isolates ofM. tuberculosis, including MDR/XDR-TB strains. Moreover, DSF showed remarkable bactericidal activityex vivoandin vivo. Therefore, DSF might be a drug repurposed for the treatment of MDR/XDR-TB.

scholarly journals Comprehensive Treatment of Extensively Drug-Resistant Tuberculosis

2008 ◽  
Vol 359 (6) ◽  
pp. 563-574 ◽  
Author(s):  
Carole D. Mitnick ◽  
Sonya S. Shin ◽  
Kwonjune J. Seung ◽  
Michael L. Rich ◽  
Sidney S. Atwood ◽  
...  
Keyword(s):  
Comprehensive Treatment ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant

scholarly journals Diagnostic Accuracy of the GenoType MTBDRslAssay for Rapid Diagnosis of Extensively Drug-Resistant Tuberculosis in HIV-Coinfected Patients

2012 ◽  
Vol 51 (1) ◽  
pp. 243-248 ◽  
Author(s):  
Irina Kontsevaya ◽  
Olga Ignatyeva ◽  
Vladyslav Nikolayevskyy ◽  
Yanina Balabanova ◽  
Alexander Kovalyov ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Rapid Diagnosis ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant

High rate of extensively drug-resistant tuberculosis in Indian AIDS patients

AIDS ◽  
2007 ◽  
Vol 21 (17) ◽  
pp. 2345-2347 ◽  
Author(s):  
Sarman Singh ◽  
Manimuthu Mani Sankar ◽  
Krishnamoorthy Gopinath
Keyword(s):  
High Rate ◽  
Drug Resistant ◽  
Aids Patients ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant
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