scholarly journals Utility of 99mTc-mebrofenin hepato-biliary scintigraphy (HIDA scan) for the diagnosis of biliary atresia

2012 ◽  
Vol 33 (1) ◽  
pp. 4-8 ◽  
Author(s):  
CS Bal
Keyword(s):  
Biliary Atresia ◽  
Hida Scan ◽  
Biliary Scintigraphy

scholarly journals Utility of Tc99m-Mebrofenin hepato-biliary scintigraphy (HIDA scan) for the diagnosis of biliary atresia

2012 ◽  
Vol 33 (1) ◽  
pp. 62-64 ◽  
Author(s):  
Ira Shah ◽  
Sushmita Bhatnagar ◽  
Venkatesh Rangarajan
Keyword(s):  
Biliary Atresia ◽  
Hida Scan ◽  
Biliary Scintigraphy

scholarly journals Role of Hepatobiliary Scintigraphy and Ultrasonography in the Diagnosis of Biliary Atresia in Infant with Neonatal Jaundice – Experiences in NINMAS

2017 ◽  
Vol 18 (1) ◽  
pp. 51-53
Author(s):  
Nasreen Sultana ◽  
Zeenat Jabin ◽  
Md Bashir ◽  
Rahima Parveen ◽  
Shamim MF Begum ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Gall Bladder ◽  
Biliary Atresia ◽  
False Positive ◽  
Hepatic Dysfunction ◽  
Hepatobiliary Scintigraphy ◽  
Hida Scan ◽  
Complementary Role

Objective: The purpose of this study was to determine whether gall bladder visualization can help to exclude the biliary atresia in hepatobiliary scintigraphic studies of infants with persistent jaundice.Methods: This is a retrospective study carried out at the National Institute of Nuclear Medicine and Allied Sciences (NINMAS). Study subjects include infants with neo-natal jaundice who underwent Hepatobiliary scintigraphies for suspected biliary atresia and study period was 2 years. Food was withheld for 4 hours before the examination. Anterior images of liver and gall bladder were taken after i/v administration of 2 -3 mci 99m Tc labeled Brida (HIDA) at 5 min interval for 2 hours then at 4 hours and 24 hours. Non-visualization of bowel activity in HIDA scan in 24hours delayed images was considered as cases of diagnosis of biliary atresia.Results: Thirty-six patients were included in this retrospective study. Patent biliary channels was seen by scintigraphies in 17(47%) patients and biliary atresia was seen in 19(52%) patients. By abdominal US non- visualization of gall bladder were found in 25(69%) cases and gall bladder visualized in 11(30%) cases. Eight (22%) of 36 patients had biopsy confirmed biliary atresia; all of these had positive scintigraphies and (60%) had positive sonographic findings. Among the 5 false-positive scintigraphies caused by hepatic dysfunction and 2 had normal sonography. Thirty-six patients had periscintigraphic sonography. There were 25/36 (61%) abnormal studies, which included cases with small gallbladder (n = 8) and non-visualized gallbladder (n = 17), but not periportal fibrosis.Conclusion: Gall bladder was usually visible on Hepatobiliary scintigraphy of fasting patients with biliary patency.  Both hepatobiliary scintigraphy and sonography are currently the standard imaging investigations for suspected biliary atresia. The complementary role, in which scintigraphy and sonography are important, and recommend follow-up imaging reassessment before making definitive surgical decisions. This will serve to decrease the frequency of false-positive imaging diagnoses of biliary atresia, and hence, avoid unnecessary surgeries.Bangladesh J. Nuclear Med. 18(1): 51-53, January 2015

scholarly journals Hepato-biliary Scintigraphy in diagnosis of Biliary Atresia

2006 ◽  
Vol 62 (1) ◽  
pp. 20-21 ◽  
Author(s):  
SS Anand ◽  
RK Handa ◽  
Jogender Singh ◽  
I Sinha
Keyword(s):  
Biliary Atresia ◽  
Biliary Scintigraphy

Differentiating Biliary Atresia from Other Causes of Cholestatic Jaundice

2014 ◽  
Vol 80 (9) ◽  
pp. 827-831 ◽  
Author(s):  
Daniel K. Robie ◽  
Sarah R. Overfelt ◽  
Li Xie
Keyword(s):  
Liver Biopsy ◽  
Biliary Atresia ◽  
Small Sample Size ◽  
Small Sample ◽  
Cholestatic Jaundice ◽  
Exact Test ◽  
Hida Scan ◽  
Operative Evaluation ◽  
Student’S T ◽  
Size Limits

Diagnosis of biliary atresia (BA) in infants presenting with cholestatic jaundice (CJ) requires exploratory surgery with cholangiography. However, the lack of a standardized approach to pre-operative evaluation of infants with CJ can lead to a high number of negative surgical explorations. We reviewed our experience with CJ and BA to determine preoperative variables that might reliably identify BA. Infants explored for possible BA over a 5–year period were retrospectively reviewed. Preoperative clinical indices and liver biopsy results were reviewed. Statistical analysis was conducted by Student's t test and Fisher's exact test ( P < 0.05). Twenty patients were identified, 10 with BA and 10 without (50% negative exploration rate). Nuclear cholescintigraphy (HIDA) excretion into the gastrointestinal tract was absent in all BA and in 8 of 10 without BA. Hepatomegaly was more common in the BA group (OR = 9.3, P = 0.07). BA had higher mean (6 standard error) serum gammaglutamyl transpeptidase levels (542 ± 130 vs 139 ± 25.8 U/L in non-BA, P = 0.03). There were insignificant differences in sex, type of feeding, TPN exposure and sepsis between the two groups. Although our small sample size limits conclusions, we suggest screening infants with CJ by measuring GGT levels, absence of hepatomegaly, presence of cholic stools and/or excretion on HIDA scan to undergo pecutaneous liver biopsy given the lower likelihood of BA necessary.

Intrahepatic biliary atresia with xanthomatosis

1966 ◽  
Vol 94 (6) ◽  
pp. 791-793 ◽  
Author(s):  
L. Shapiro
Keyword(s):  
Biliary Atresia

Loss of gap junctions in biliary atresia occurs simultaneously with declined expression of Protein kinase Cα

2015 ◽  
Vol 53 (01) ◽  
Author(s):  
JHK Andruszkow ◽  
S Groos ◽  
C Klaus ◽  
U Schneider ◽  
C Petersen ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Gap Junctions ◽  
Biliary Atresia ◽  
Protein Kinase Cα

Epidemiologic Study of Infants With Biliary Atresia

PEDIATRICS ◽  
1998 ◽  
Vol 101 (4) ◽  
pp. 729-730 ◽  
Author(s):  
M. Davenport ◽  
A. Dhawan; ◽  
P. Yoon ◽  
J. S. Bresee ◽  
R. S. Olney ◽  
...  
Keyword(s):  
Biliary Atresia ◽  
Epidemiologic Study
Sign in / Sign up

Export Citation Format

Share Document