scholarly journals A Color Doppler Imaging Study of Ocular Haemodynamic Parameters in Normal Tension Glaucoma

2019 ◽  
Vol 29 (4) ◽  
Author(s):  
Atif Rahman Raini
Keyword(s):  
Color Doppler ◽  
Imaging Study ◽  
Color Doppler Imaging ◽  
Normal Tension Glaucoma ◽  
Doppler Imaging ◽  
Haemodynamic Parameters

scholarly journals Color Doppler Imaging Analysis of Ocular Blood Flow Velocities in Normal Tension Glaucoma Patients: A Meta-Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-24 ◽  
Author(s):  
Shuo Xu ◽  
Shouyue Huang ◽  
Zhongjing Lin ◽  
Wangmin Liu ◽  
Yisheng Zhong
Keyword(s):  
Color Doppler ◽  
Meta Analysis ◽  
Color Doppler Imaging ◽  
Normal Tension Glaucoma ◽  
Diagnostic Value ◽  
Doppler Imaging ◽  
Diagnostic Tools ◽  
Significant Heterogeneity ◽  
Cochrane Central Register ◽  
Ischemic Change

Background. To evaluate the potential diagnostic value of CDI of retrobulbar hemodynamic changes in NTG patients.Methods. Relevant publications which included PSV, EDV, and RI of OA, CRA, NPCA, and TPCA in NTG patients and normal controls measured by CDI were retrieved from the Cochrane Central Register of Controlled Trials, PubMed, the ISI Web of Knowledge, and EMBASE from 1990 to 2014. Subgroup analyses were made based on IOP-lowering medications uses.Result. In OA, there was significant decrease of PSV with moderate heterogeneity (P<0.00001,I2=49%) and significant decrease of EDV with significant heterogeneity (P=0.0005,I2=87%) in NTG patients. In CRA, similar results of PSV (P<0.00001,I2=42%) and EDV (P<0.00001,I2=80%) were detected. Significant decrease of PSV and EDV with significant heterogeneity was also found in both NPCA (P<0.0001,I2=70%;P<0.0001,I2=76%; resp.) and TPCA (P<0.00001,I2=54%;P<0.00001,I2=65%; resp.). Statistically significant increases of RI were found in CRA (P=0.0002,I2=89%) and TPCA (P=0.02,I2=81%) with significant heterogeneities, though RI in OA (P=0.25,I2=94%) and in NPCA (P=0.15,I2=86%) showed no statistical changes with significant heterogeneities.Conclusions. Ischemic change of retrobulbar hemodynamics is one of the important manifestations of NTG. Hemodynamic parameters measured by CDI might be potential diagnostic tools for NTG.

scholarly journals Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Mitsushi Fukukita ◽  
Masashi Ido ◽  
Syunsuke Osawa ◽  
Mikio Sasoh ◽  
Motoyasu Furuta ◽  
...  
Keyword(s):  
Color Doppler ◽  
Resistance Index ◽  
Color Doppler Imaging ◽  
Normal Tension Glaucoma ◽  
Ocular Blood Flow ◽  
Doppler Imaging ◽  
Eye Drops ◽  
Ciliary Arteries ◽  
Retinal Artery ◽  
Retrobulbar Hemodynamics

Purpose. To investigate the effects of nipradilol on retrobulbar hemodynamics.Methods. We investigated normal and normal-tension glaucoma (NTG) eyes. Topical nipradilol (one eye) and placebo eye drops (fellow eye) were instilled for 1 week in volunteers. Nipradilol was also instilled in NTG patients. Ultrasound color Doppler imaging for the posterior vessels was performed before, 2 hr, 1 week (for normal), and at 4 weeks (for NTG).Results. In normal eyes, there were significant decreases in the resistance index (RI) for the temporal short posterior ciliary arteries (PCA) at 2 hr and for the ophthalmic arteries at 1 week. There were no significant changes in the placebo-treated eyes. In the NTG eyes, there was a significant decrease in the RI for the central retinal artery, nasal, and temporal PCA at 2 hr and 4 weeks.Conclusion. Short-term observations found that nipradilol increased the ocular blood flow in normal and NTG eyes.

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