Measurement of the Human Calcaneus In Vivo Using Ultrasonic Backscatter Spectral Centroid Shift

2016 ◽  
Vol 35 (10) ◽  
pp. 2197-2208 ◽  
Author(s):  
Chengcheng Liu ◽  
Feng Xu ◽  
Dean Ta ◽  
Tao Tang ◽  
Yunqi Jiang ◽  
...  
2003 ◽  
Author(s):  
Keith A. Wear ◽  
Brian S. Garra ◽  
Melanie C. Pinet ◽  
Steven Felker ◽  
Jonathan Mai

1995 ◽  
Vol 98 (4) ◽  
pp. 1852-1857 ◽  
Author(s):  
Keith A. Wear ◽  
Brian S. Garra ◽  
Timothy J. Hall

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Weiying Mao ◽  
Yang Du ◽  
Chengcheng Liu ◽  
Boyi Li ◽  
Dean Ta ◽  
...  

Metabolic bone disease (MBD) is one of the major complications of prematurity. Ultrasonic backscatter technique has the potential to be a portable and noninvasive method for early diagnosis of MBD. This study firstly applied CAS to neonates, which was defined as a linear combination of the apparent integrated backscatter coefficient (AIB) and spectral centroid shift (SCS). The objective was to evaluate the feasibility of ultrasonic backscatter technique for assessing neonatal bone health using AIB, SCS, and CAS. Ultrasonic backscatter measurements at 3.5 MHz, 5.0 MHz, and 7.5 MHz were performed on a total of 505 newborns within 48 hours after birth. The values of backscatter parameters were calculated and compared among gestational age groups. Correlations between backscatter parameters, gestational age, anthropometric indices, and biochemical markers were analyzed. The optimal predicting models for CAS were determined. The results showed term infants had lower SCS and higher AIB and CAS than preterm infants. Gestational age and anthropometric indices were negatively correlated with SCS (|r| = 0.45 – 0.57, P < 0.001), and positively correlated with AIB (|r| = 0.36 – 0.60, P < 0.001) and CAS (|r| = 0.56 – 0.69, P < 0.001). Biochemical markers yielded weak or nonsignificant correlations with backscatter parameters. CAS had relatively stronger correlations with the neonatal variables than AIB and SCS. At 3.5 MHz and 5.0 MHz, only gestational age (P < 0.001) independently contributed to the measurements of CAS, and could explain up to 40.5% – 44.3% of CAS variation. At 7.5 MHz, the combination of gestational age (P < 0.001), head circumference (P = 0.002), and serum calcium (P = 0.037) explained up to 40.3% of CAS variation. This study suggested ultrasonic backscatter technique was feasible to evaluate neonatal bone status. CAS was a promising parameter to provide more information about bone health than AIB or SCS alone.


IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 157417-157426 ◽  
Author(s):  
Weiying Mao ◽  
Yang Du ◽  
Chengcheng Liu ◽  
Boyi Li ◽  
Dean Ta ◽  
...  

1980 ◽  
Vol 2 (1) ◽  
pp. 67-77 ◽  
Author(s):  
J. Ophir ◽  
A. Gobuty ◽  
R. E. McWhirt ◽  
N. F. Maklad

Measurements of ultrasonic backscatter from solid collagen microspheres in suspension and from a standard erythrocyte suspension were performed. When normalized to a standard particle size and concentration, the back-scatter from the collagen was 29.6 dB above that of the erythrocytes. An in vivo canine experiment using commercial diagnostic equipment demonstrated enhanced backscatter from the liver after intravenous injection of the microspheres. Calculations show that the in vivo enhancement cannot be explained from the earlier studies. Possible mechanisms responsible for this effect are proposed.


1998 ◽  
Vol 24 (1) ◽  
pp. 79-91 ◽  
Author(s):  
R.C. Molthen ◽  
V.M. Narayanan ◽  
P.M. Shankar ◽  
J.M. Reid ◽  
V. Genis ◽  
...  

1983 ◽  
Vol 5 (2) ◽  
pp. 117-135 ◽  
Author(s):  
M. Fink ◽  
F. Hottier ◽  
J.F. Cardoso

Short-time Fourier analysis is well suited for processing tissue echographic signals which are nonstationary. We have investigated the use of short-time Fourier analysis to provide an estimation of the echographic spectral composition as a function of time. It will be shown that the time dependence of the spectral centroid of this representation allows one to deduce easily the frequency-dependent attenuation. A simple correction of the noninvariant filtering effect due to diffraction is used to unbias the attenuation slope estimation. This new signal processing technique was first tested on simulated echographic data from a 1-D tissue model. Experimental results obtained from echo signals on a tissue-like phantom and on in vivo liver tissue show the influence of diffraction and attenuation respectively.


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