Role of Sonographic Elastography in the Differential Diagnosis of Axillary Lymph Nodes in Breast Cancer

2011 ◽  
Vol 30 (4) ◽  
pp. 429-436 ◽  
Author(s):  
Jae Jeong Choi ◽  
Bong Joo Kang ◽  
Sung Hun Kim ◽  
Ji Hye Lee ◽  
Seung Hee Jeong ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Differential Diagnosis ◽  
Lymph Nodes ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Sonographic Elastography

scholarly journals Value of Ultrasound in Evaluation of Abnormal Axillary Lymph Node

2021 ◽  
Vol 4 ◽  
pp. 3
Author(s):  
Abdelmohsen Radwan Hussien ◽  
Monaliza El-Quadi ◽  
Avice Oconnell
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Cancer Treatment ◽  
Axillary Lymph Node ◽  
Breast Cancer Treatment ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph

Understanding of the various appearances of axillary lymph nodes (LNs) is essential for diagnosing and planning of breast cancer treatment. In this article, the role of ultrasound in detecting abnormal appearing metastatic LNs s is discussed, with emphasis on most of the ultrasonographic features and tools which might help improve detection of axillary LN pathology.

scholarly journals Characterization of Axillary Lymph Nodes as Normal, Reactive and Benign Using Conventional Ultrasonography

2016 ◽  
Vol 14 (1) ◽  
pp. 8-16
Author(s):  
Farzana Alam ◽  
Md. Menhazul Islam ◽  
Mahbuba Shirin ◽  
Sayeeda Shawkat ◽  
Salahuddin Al Azad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Differential Diagnosis ◽  
Lymph Nodes ◽  
Healthy Woman ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Short Axis ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Axis Ratio

Background: Detection of abnormalities of axillary lymph nodes is important for the diagnosis of different pathologies. Objective: The purpose of this present study was to see the accuracy of conventional USG for the differential diagnosis of axillary lymph nodes. Methodology: This cross sectional study was carried out in the Department of Radiology & Imaging at Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2012 to June 2013 for a period of one year. Normal healthy woman who came for screening of breast disease without any symptoms and did not have any abnormality on USG was included as normal patient. Axillary lymph nodes from these normal patients were categorized as benign lymph nodes. Patients, who came with the complaints of mastalgia with normal breast findings, were included as patients with mastalgia. The lymph nodes from the patients of mastalgia were considered as reactive lymph nodes and patients with known breast cancer and lymph node metastasis were included as malignant patients. Metastatic lymph nodes from breast cancer patients were included. Result: In benign vs reactive the area under curve for long axis diameter was 0.534 (p=0.307), short axis diameter was 0.589 (p=0.007), sinus length 0.492 (p=0.798), cortical thickness was 0.684 (p=0.0001) short long ratio was 0.570 (p=0.033), sinus long ratio 0.445 (p=0.095) cortex short axis ratio 0.641 (p=0.0001). Conclusion: The accuracy of conventional USG is good diagnostic modalities for the differential diagnosis of axillary lymph nodes.Journal of Science Foundation, January 2016;14(1):8-16

Comparative evaluation of strain ratio on sonographic elastography and T2* values on 3 Tesla magnetic resonance imaging in differentiating malignant from benign axillary lymph nodes in breast cancer

2021 ◽  
Vol 9 (4) ◽  
pp. 1156
Author(s):  
Shweta Sharma ◽  
Richa Bansal ◽  
Shubham Jain
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Sensitivity And Specificity ◽  
Roc Curve ◽  
Predictive Value ◽  
Strain Ratio ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Linear Probe ◽  
Sonographic Elastography

Background: The study aimed to assess whether strain ratio and T2* values can improve the sensitivity and specificity of differentiating metastatic from benign axillary lymph nodes in breast cancer patients taking histopathology as reference standard.Methods: The study was done on 43 patients. A multi-echo transverse T2*W MR sequence was obtained with TE = 0.9- 1.5 ms, TR=37.2 ms and flip angle = 25°. Sonographic elastography was done using high frequency linear probe (L3-16 MHz). Manual selection of the region of interest was done on suspicious lymph nodes for calculation of T2* values and strain ratio. ROC curves were obtained for various T2* and strain ratio values in comparison to histopathological findings as gold standard.Results: Correlation with histopathology was better with T2* values than strain ratio. The sensitivity and specificity were calculated using cut off values obtained from ROC curve (31.225 ms for T2* value and 1.85 for SR) and were 70.37%, 68.75% for strain ratio and 96.29%, 93.75% for T2* value respectively. The positive predictive value and negative predictive value were also assessed, values being higher for T2* than strain ratio. Comparison of areas under ROC curve was statistically significant with p=0.018.Conclusions: T2* can be used as a potential biomarker for differentiating metastatic from benign axillary lymph nodes owing to its high sensitivity, specificity and relative ease of performance. Quantitative assessment of changes in T2* values may allow more objective analysis of signal changes with significant differences between benign and malignant lymph nodes, even in case of partial infiltration. 

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