scholarly journals Poststreptococcal Reactive Arthritis: Diagnostic Challenges

2019 ◽  
Keyword(s):  
Reactive Arthritis ◽  
Poststreptococcal Reactive Arthritis

scholarly journals FRI0445 HLA-B27 IN POSTSTREPTOCOCCAL REACTIVE ARTHRITIS WITH ENTHESITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 820.1-820
Author(s):  
I. Naishtetik ◽  
L. Khimion ◽  
O. Yashchenko ◽  
P. Dolinskiy
Keyword(s):  
Rheumatic Fever ◽  
Reactive Arthritis ◽  
Streptococcal Infection ◽  
Joint Involvement ◽  
Hla B27 ◽  
Aseptic Inflammation ◽  
Beta Hemolytic Streptococcus ◽  
Common Diagnosis ◽  
Poststreptococcal Reactive Arthritis ◽  
Rheumatology Practice

Background:Poststreptococcal reactive arthritis (PSRA) is a very common diagnosis in rheumatology practice, which develops after recent pharyngeal streptococcal infection and characterized by aseptic inflammation in one or more joints and periarticular involvement. Now no diagnostic criteria have been agreed [2,4]; association of the expression of HLA-B27 and PSRA is not clear [1,3].Objectives:In our study we analyzed the features of PSRA in presence of HLA-B27.Methods:88 patients (48 female and 40 male) aged between 18-55 years with complains of pain, tender and swollen joints developed after recent pharyngeal streptococcal infection underwent standard physical and laboratory rheumatological examinations. Acute rheumatic fever and other inflammatory arthritis were excluded.Results:60 patients (68,2%) had oligo-polyarthralgia, 10 patients (11,4%) - monoarthritis, 24 patients (27,3%) had asymmetrical olygoarthritis, 4 patients (4,5%) had polyarthritis, enthesitis was found in 4 (4,5%) patients, tenosynovitis of the palmar flexor tendons in 10 cases (11,4%) and the peroneal tendons of the ankles in 5 patients (5,7%), one-sided sacroiliitis (confirmed by MRI) in 5 patients (5,7%).The mean level of ASL-O was 542 U/ml, CRP -15 mg/L, ESR - 34 mm/H; HLA-B27 was present in 24 (30,7%) patients. HLA-B27 positivity was connected to enthesitis, sacroiliitis, more joint involvement with higher levels of ESR and CRP.Conclusion:30% of patients with poststreptococcal reactive arthritis are HLA-B27 positive, the presence of HLA-B27 leads to more frequent development of enthesitis, polyarthritis and sacroiliitis with higher level of inflammatory activity which dictate the need for longer supervision of such patients for possible triggering of ankylosing spondylitis development.References:[1]Ahmed S, Ayoub EM, ScorniK JC, Wang C-Y, She J-X. Poststreptococcal reactive arthritis. Clinical characteristics and association with YLA-DR alleles. Arthritis Rheum 1998; 41:1096-102.9[[2]Gibofsky A, Khanna A, Suh E, et al. The genetics of rheumatic fever: Relationship to streptococcal infection and autoimmune disease. J Rheumatol Suppl. 1991;30:1–5. [PubMed] [Google Scholar][3]Leitch DN, Holland CD/ Reactive arthritis, beta-hemolytic Streptococcus and Staphylococcus aureus. Br J Rheumatol 1996;35:912.[4]Mackie SL, Keat A. Poststreptococcal reactive arthritis: what is it and how do we know? Rheumatology (Oxford) 2004;43:949–54. 10.1093/rheumatology/keh225 [PubMed].Disclosure of Interests:None declared

Use of Adalimumab in Poststreptococcal Reactive Arthritis

2007 ◽  
Vol 13 (3) ◽  
pp. 176 ◽  
Author(s):  
Daniel S??nchez-Cano ◽  
Jos?? Luis Callejas-Rubio ◽  
Norberto Ortego-Centeno
Keyword(s):  
Reactive Arthritis ◽  
Poststreptococcal Reactive Arthritis

Poststreptococcal reactive arthritis and tonsillitis induced reactive arthritis

2003 ◽  
Vol 1257 ◽  
pp. 151-154 ◽  
Author(s):  
Shigeto Kobayashi ◽  
Naoto Tamura ◽  
Makoto Ikeda ◽  
Kazuhiko Harua ◽  
BinBin Zhong ◽  
...  
Keyword(s):  
Reactive Arthritis ◽  
Poststreptococcal Reactive Arthritis

scholarly journals No increased risk of valvular heart disease in adult poststreptococcal reactive arthritis

2009 ◽  
Vol 60 (4) ◽  
pp. 987-993 ◽  
Author(s):  
J. M. van Bemmel ◽  
V. Delgado ◽  
E. R. Holman ◽  
C. F. Allaart ◽  
T. W. J. Huizinga ◽  
...  
Keyword(s):  
Heart Disease ◽  
Valvular Heart Disease ◽  
Reactive Arthritis ◽  
Increased Risk ◽  
Poststreptococcal Reactive Arthritis

Poststreptococcal Reactive Arthritis

2006 ◽  
Vol 96 (4) ◽  
pp. 362-366 ◽  
Author(s):  
Daniel Logan ◽  
Patrick J. McKee
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Lower Extremity ◽  
Rheumatic Fever ◽  
Reactive Arthritis ◽  
Acute Rheumatic Fever ◽  
Streptococcal Infection ◽  
Treatment Options ◽  
Review Of The Literature ◽  
Poststreptococcal Reactive Arthritis

Acute rheumatic fever is a delayed inflammatory disease that follows streptococcal infection of the throat. Poststreptococcal reactive arthritis is a sterile arthritis associated with antecedent streptococcal infection in patients not fulfilling the Jones criteria for acute rheumatic fever. Poststreptococcal reactive arthritis has been reported to have lower-extremity predominance and, therefore, should be included in the differential diagnosis of patients with lower-extremity arthritis. A review of the literature, distinguishing poststreptococcal reactive arthritis from acute rheumatic fever, and treatment options are discussed here. A case report is also presented. (J Am Podiatr Med Assoc 96(4): 362–366, 2006)

Uveitis in Adult Patients with Poststreptococcal Reactive Arthritis: the First Two Cases Reported associated with Uveitis

2002 ◽  
Vol 21 (6) ◽  
pp. 533-535 ◽  
Author(s):  
S. Kobayashi ◽  
N. Tamura ◽  
M. Ikeda ◽  
K. Sakuraba ◽  
T. Matsumoto ◽  
...  
Keyword(s):  
Reactive Arthritis ◽  
Adult Patients ◽  
Poststreptococcal Reactive Arthritis

Poststreptococcal Reactive Arthritis and the Association With Tendonitis, Tenosynovitis, and Enthesitis

2010 ◽  
Vol 16 (1) ◽  
pp. 3-6 ◽  
Author(s):  
Housam Aldeen Sarakbi ◽  
Mohammed Hammoudeh ◽  
Izzat Kanjar ◽  
Samar Al-Emadi ◽  
Salah Mahdy ◽  
...  
Keyword(s):  
Reactive Arthritis ◽  
Poststreptococcal Reactive Arthritis

Poststreptococcal Reactive Arthritis and Silent Carditis: A Case Report and Review of the Literature

PEDIATRICS ◽  
1994 ◽  
Vol 93 (5) ◽  
pp. 837-839
Author(s):  
Frederick M. Schaffer ◽  
Ravinder Agarwal ◽  
Jutta Helm ◽  
Robert L. Gingell ◽  
J. Michael A. Roland ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Heart Disease ◽  
Case Report ◽  
North America ◽  
Reactive Arthritis ◽  
Acute Rheumatic Fever ◽  
Review Of The Literature ◽  
Poststreptococcal Reactive Arthritis ◽  
Pediatric Heart Disease

Between 1984 and 1988, a resurgence of acute rheumatic fever (ARF) was reported in several pediatric centers.1-3 During the same time, pediatric cases,4-6 and, recently, adult cases6 of poststreptococcal reactive arthritis (PSRA) have been reported. Although several of these patients had or developed multisystemic manifestations,4,5 none of these cases fully adhered to the guidelines of the revised Jones criteria.7 Thus, these individuals were given the diagnosis of PSRA or poststreptococcal rheumatic syndrome (PSRS) rather than ARF.4-6,8-10 One of the leading causes of acquired pediatric heart disease in North America is carditis of ARF,3 and severe cases can result in congestive heart failure, the need for valve replacement, or death.11

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