scholarly journals Inhibitory Activity of Bacillus subtilis BCC 6327 Metabolites against Growth of Aflatoxigenic Fungi Isolated from Bird Chili Powder

2013 ◽  
pp. 27-32 ◽  
Author(s):  
Rattanaporn Thakaew ◽  
Hataichanoke Niamsup
Keyword(s):  
Bacillus Subtilis ◽  
Inhibitory Activity ◽  
Aflatoxigenic Fungi ◽  
Chili Powder

The Study of Bacillus Subtils Antimicrobial Activity on Some of the Pathological Isolates

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Hussein A Kadhum ◽  
Thualfakar H Hasan2
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Bacterial Growth ◽  
Broad Spectrum ◽  
Inhibitory Activity ◽  
Bacterial Pathogens ◽  
Inhibitory Ability ◽  
Selection Of

The study involved the selection of two isolates from Bacillus subtilis to investigate their inhibitory activity against some bacterial pathogens. B sub-bacteria were found to have a broad spectrum against test bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. They were about 23-30 mm and less against Klebsiella sp. The sensitivity of some antibodies was tested on the test samples. The results showed that the inhibitory ability of bacterial growth in the test samples using B. subtilis extract was more effective than the antibiotics used.

scholarly journals Lysozyme inhibitory activity of DNA from Bacillus subtilis I-139.

1990 ◽  
Vol 54 (5) ◽  
pp. 1289-1290 ◽  
Author(s):  
San-Lang WANG ◽  
Sawao MURAO ◽  
Motoo ARAI
Keyword(s):  
Bacillus Subtilis ◽  
Inhibitory Activity

Application of Topological Descriptors in QSAR Modeling: Substituted Hydrazones Used As a Model System

2020 ◽  
Vol 17 (3) ◽  
pp. 253-263
Author(s):  
Vesna Dimova ◽  
Mirjana Stojan Jankulovska
Keyword(s):  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Inhibitory Activity ◽  
Candida Utilis ◽  
Topological Descriptors ◽  
Projection Area ◽  
Statistical Parameters ◽  
Qsar Study ◽  
Qsar Models

Background: QSAR study of p-substituted aromatic hydrazones was performed to estimate the quantitative effects of selected topological descriptors on their antimicrobial activity. None of the hydrazones inhibited the growth of the Aspergillus spp., while the data obtained with regard to the antifungal activity of the compounds against Candida utilis were insufficient to develop reliable statistical QSAR models. Therefore, the investigation was focused on developing QSAR models for predicting the antibacterial activity of the compounds against Bacillus subtilis. Methods: A set of substituted hydrazones were tested for their in vitro growth inhibitory activity against Candida utilis, Bacillus subtilis and Aspergillus niger and the diameter of the inhibition zone (mm) was measured. The inhibitory activity data, determined in μg/mL, were transformed to the negative logarithms of molar MICs (log1/CMIC). Using Marvinsketch software package, 28 topological descriptors were calculated. Statistical parameters, such as R2, Sd, F-test, R2 adj, Q, SPRESS, PSE and Q2, were used to test the quality of the developed two-, three-, four-parametric and higher QSAR models. Results and Conclusion: Statistical evaluation of the data used to test the quality of the obtained QSAR models indicated that the two-parametric model involving the descriptors Atom Count (AC) and Maximal Projection Area (MAPA) was statistically significant when all the statistical parameters were summarized. The two parameters, AC and MAPA, had opposite input in modeling the antimicrobial activity of the selected hydrazones against Bacillus subtilis.

Sign in / Sign up

Export Citation Format

Share Document