Three-Dimensional Numerical Analysis of Pulsatile Blood Flow around Different Plaque Shapes in Human Carotid Artery

2012 ◽  
pp. 305-308
Author(s):  
Absaar Ul Jabbar ◽  
Rana Usman Ali ◽  
Khalid Parvez ◽  
Umar H. K. Niazi
Keyword(s):  
Blood Flow ◽  
Numerical Analysis ◽  
Carotid Artery ◽  
Three Dimensional ◽  
Pulsatile Blood Flow ◽  
Human Carotid

Three Dimensional Numerical Analysis of Flow Through the Human Carotid Bifurcation With Varying Degrees of Stenotic Plaque Formation

2007 ◽  
Author(s):  
Scott T. Lovald ◽  
Tariq Khraishi ◽  
Juan C. Heinrich ◽  
Howard Yonas ◽  
Christopher L. Taylor
Keyword(s):  
Numerical Analysis ◽  
Carotid Artery ◽  
Three Dimensional ◽  
Carotid Bifurcation ◽  
Local Flow ◽  
Flow Through ◽  
High Degree ◽  
The Brain ◽  
Insight Into ◽  
Human Carotid

The human carotid artery bifurcation is often affected by plaque and atherosclerotic formations. A high degree of stenosis due to plaque deposit in the carotid artery can significantly diminish blood flow to the brain [1]. For three decades, local flow anomalies such as flow separation, recirculation, low wall shear stress, and high local particle residence time are factors that have been implicated in the development of arterial diseases [3, 1]. Numerical analysis of flow through a stenotic carotid bifurcation provides insight into local flow dynamics and an assessment of the risks of particular modes and degrees of stenosis.

SIMULATION OF PULSATILE BLOOD FLOW THROUGH STENOTIC ARTERY CONSIDERING DIFFERENT BLOOD RHEOLOGIES: COMPARISON OF 3D AND 2D-AXISYMMETRIC MODELS

2013 ◽  
Vol 25 (02) ◽  
pp. 1350023 ◽  
Author(s):  
Safoora Karimi ◽  
Mitra Dadvar ◽  
Mahsa Dabagh ◽  
Payman Jalali ◽  
Hamid Modarress ◽  
...  
Keyword(s):  
Blood Flow ◽  
Carotid Artery ◽  
3D Model ◽  
Flow Behavior ◽  
Three Dimensional ◽  
3D Models ◽  
Secondary Flows ◽  
Pulsatile Blood Flow ◽  
Axisymmetric Model ◽  
Symptomatic Carotid

Hemodynamic factors such as velocity distribution, pressure gradient and wall shear stress are thought to play an important role in the prognosis of symptomatic carotid occlusion. Although there are many studies about modeling the blood flow behavior in carotid, hemodynamic characteristics of blood flow in a stenosed carotid artery is still debatable. In this study a three-dimensional (3D) model of a symmetric stenosed common carotid artery (CCA) is developed and the simulation results of it are compared to the experimental data where subsequent agreement is confirmed. To study the accuracy of two-dimensional (2D) axisymmetric model, the result of it is compared to the result of the 3D model. Two non-Newtonian rheological models, namely Carreau and modified Power-law, as well as Newtonian model are used to realize the hemodynamical differences of 2D-axisymmetric and 3D models in pulsatile blood flow. Comparing the 3D simulated results with 2D-axisymmetric modeling results that were published in recent years indicates that the assumption of 2D-axisymmetric model cannot adequately predict the velocity profiles even for a symmetric stenotic artery. Although a symmetric stenotic artery is considered, the results indicate a nonsymmetric flow in poststenosis region that is detected by the presence of extensive secondary flows particularly at diastole. The existence of secondary flows that can only be detected in 3D modeling is the main reason for the differences in hemodynamic factors in 3D and 2D results.

In Vitro Three Dimensional Imaging of Human Carotid Atherosclerotic Plaques Using Ultrasonography

2011 ◽  
Author(s):  
Renate W. Boekhoven ◽  
Marcel C. M. Rutten ◽  
Marc R. H. M. van Sambeek ◽  
Frans N. van de Vosse
Keyword(s):  
Mechanical Properties ◽  
Carotid Artery ◽  
Carotid Endarterectomy ◽  
Early Stage ◽  
Three Dimensional ◽  
Atherosclerotic Plaques ◽  
Unstable Plaques ◽  
Human Carotid ◽  
Selection Of

Ruptured atherosclerotic plaques in the carotid artery are the main cause of stroke (70–80%). To prevent it, carotid endarterectomy is the procedure of choice in patients with a recent symptomatic 70–99% stenosis. Today, the selection of candidates is based on stenosis size only. However, endarterectomy is beneficial for only 1 out of 6 patients [1], the patients with unstable plaques (Fig. 1). Knowledge of mechanical properties of different components in the atherosclerotic arteries is important, because it will allow the identification of plaque stability at an early stage.

Smooth Mesh Generation for Numerical Analysis of Blood Vessel Fluid Flow

2011 ◽  
Author(s):  
Juraj Culak ◽  
Yulia V. Peet ◽  
David L. Chopp
Keyword(s):  
Blood Flow ◽  
Image Segmentation ◽  
Fluid Flow ◽  
Numerical Analysis ◽  
Carotid Artery ◽  
Blood Vessel ◽  
Mesh Generation ◽  
Patient Specific ◽  
High Quality

A Matlab-based approach to image segmentation and mesh generation for creating high-quality hexagonal meshes is developed. The successful use of the procedure in patient-specific simulations of blood flow in a carotid artery is demonstrated.

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