scholarly journals Novel Use of Calcimimetic Activity to Diagnose Primary Hyperparathyroidism in a Patient With Persistently Low-Normal Parathyroid Hormone Level

Cureus ◽  
2020 ◽  
Author(s):  
Sindhura Bandaru ◽  
Sukesh Manthri ◽  
Deepika Nallala ◽  
Chaitanya K Mamillapalli ◽  
Michael G Jakoby
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Hormone Level ◽  
Parathyroid Hormone Level

Concomitant Graves’ disease and primary hyperparathyroidism: clinical implications and preoperative localization of parathyroid adenoma by fine needle biopsy

Open Medicine ◽  
2006 ◽  
Vol 1 (3) ◽  
pp. 298-305
Author(s):  
Michael Thalhammer ◽  
Amra Cuk ◽  
Heinz Pitzl ◽  
Klaus-Dieter Palitzsch
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Hormone Level ◽  
Needle Aspiration ◽  
Graves Disease ◽  
Parathyroid Hormone Level ◽  
Normal Range ◽  
Fine Needle

AbstractA 53-year old female patient, who presented with retrosternal pain, which could be ascribed to reflux oesophagitis and gastritis, furthermore stated recurrent palpitations, sweating and the feeling of uneasiness. In routine laboratory investigation hyperthyroidism and hypercalcaemia were detected. Further testing revealed elevated TSH receptor antibodies and a parathyroid hormone level within the normal range. Scintigraphically a homogeneous, but increased uptake was found. In ultrasonography guided fine needle aspiration biopsy of a nodule parathyroid hormone was verifiable by immunochemical means.Under thyrostatic treatment with carbimazole the patient became euthyroid, simultaneous a decrease of serum calcium levels could be observed. Parathyroid hormone level remained in normal range. After confirmation of Graves’ disease and adenoma of the parathyroid gland parathyroidectomy in combination with near total resection of the thyroid gland was performed. In conclusions concomitant Graves’ disease and primary hyperparathyroidism is rare, but should be considered in case of persisting hypercalcaemia after the patient became euthyroid again, when parathyroid hormone level is in normal range or elevated. Thus a potentially required second operation can be avoided. By ultrasonography guided fine needle aspiration biopsy and immunochemical processing adenomas of parathyroid glands can be localized preoperatively.

scholarly journals IMPACT OF SUBCLINICAL PRIMARY HYPERPARATHYROIDISM ON CARDIOVASCULAR MANIFESTATIONS OF ESSENTIAL ARTERIAL HYPERTENSION

2012 ◽  
Vol 67 (11) ◽  
pp. 53-58
Author(s):  
B. G. Iskenderov ◽  
O. N. Sisina
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Hormone Level ◽  
Left Ventricular ◽  
Parathyroid Hormone Level ◽  
Functional Remodeling ◽  
Essential Arterial Hypertension ◽  
Artery Remodeling

At 95 patients with essential arterial hypertension features of structural and functional remodeling of left ventricular and humeral artery depending on a level parathyroid hormone in blood are studied. It is shown that while increasing of plasma parathyroid hormone level frequency and expressiveness of left ventricular and humeral artery remodeling increases whereas diastolic function and endothelium-dependent vasodilatation considerably decrease. Subclinical primary hyperparathyroidism in patients with essential arterial hypertension is detected in 22,1% of cases. 

The relationship between adenoma weight and intact (1–84) parathyroid hormone level in primary hyperparathyroidism

1992 ◽  
Vol 163 (3) ◽  
pp. 301-304 ◽  
Author(s):  
J.Graham Williams ◽  
Malcolm H. Wheeler ◽  
J.Paul Aston ◽  
Richard C. Brown ◽  
J.Stuart Woodhead
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Hormone Level ◽  
Parathyroid Hormone Level ◽  
The Relationship

scholarly journals Chondrocalcinosis: An Early Sign of Primary Hyperparathyroidism

Doctor Ru ◽  
2020 ◽  
Vol 19 (11) ◽  
pp. 52-55
Author(s):  
M.S. Eliseev ◽  
◽  
A.M. Novikova ◽  
O.V. Zhelyabina ◽  
◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Storage Disease ◽  
Hormone Level ◽  
Calcium Pyrophosphate ◽  
Parathyroid Hormone Level ◽  
X Ray ◽  
Life Threatening ◽  
Normal Calcium

Objective: To deeply analyse a case of a patient with calcium pyrophosphate crystal storage disease, where chondrocalcinosis (CC) preceded primary hyperparathyroidism (PHPT). Key Points. The association of CC and hyperparathyroidism is well-known; and CC is recognised as one of the late signs of hyperparathyroidism. We describe a 67-year old patient with PHPT, presenting for a long time only with X-ray CC and chronic arthritis, associated with calcium pyrophosphate deposits. At the same time, he did not have any electrolyte imbalances, had normal serum calcium and parathyroid hormone levels; PHPT was diagnosed after 10 years of follow-up when the patient developed life-threatening hypercalcemia. It can be assumed that, unlike other musculoskeletal signs, CC can be one of the earliest symptoms of hyperparathyroidism. Treating CC as a late sign of hyperparathyroidism is likely to be associated with challenges of early diagnosis (asymptomatic in some patients, low sensitivity of X-ray diagnostics). In order to assess the diagnostic value of CC in hyperparathyroidism, including patients with normal calcium levels, specific tests are essential. Conclusion. Target examination for CC using highly-sensitive methods in patients with minor calcium metabolism disturbances, high/normal parathyroid hormone level or slightly increased parathyroid hormone level and normal calcium can improve the detection frequency of both CC and PHPT and follow-up of such patients. Early PHPT diagnosis (prior to clinical presentation) can help in preventing severe, life-threatening complications. Keywords: chondrocalcinosis, primary hyperparathyroidism, parathyroid hormone, calcium pyrophosphate crystal storage disease, hypercalcemia.

Minimally elevated preoperative parathyroid hormone level influences the management of primary hyperparathyroidism

2017 ◽  
Vol 128 (4) ◽  
pp. 1016-1021
Author(s):  
Nader Sadeghi ◽  
Ning-Wei Li ◽  
Tom Shokri ◽  
Esma Akin ◽  
Arjun S. Joshi ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Hormone Level ◽  
Parathyroid Hormone Level
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