scholarly journals Aspergillus flavus Infection of Lower Limb in an Immune-Competent Patient

Cureus ◽  
2020 ◽  
Author(s):  
Terrence Jose Jerome ◽  
Lakshmi Kandasamy ◽  
Thirumagal Kuppusamy Terrence ◽  
Suresh Bhalaji ◽  
Bhuvaneswari Shanmugasundaram
Keyword(s):  
Aspergillus Flavus ◽  
Lower Limb ◽  
Competent Patient

Severe Sepsis with DIC due to Capnocytophaga Canimorsus after Dog Bite in an Immune Competent Patient leading to subsequent Lower Limb Amputationa

2018 ◽  
Vol 08 (02) ◽  
Author(s):  
Leonie Grossekettler ◽  
Vedat Schwenger ◽  
Bastian Schmack ◽  
Hugo A Katus ◽  
Michael R Preusch
Keyword(s):  
Severe Sepsis ◽  
Lower Limb ◽  
Dog Bite ◽  
Capnocytophaga Canimorsus ◽  
Competent Patient

scholarly journals Coinfection with Lichtheimia corymbifera and Aspergillus flavus in an Immune-Competent Patient Mimicking as Pulmonary-Renal Syndrome

2017 ◽  
Vol 182 (7-8) ◽  
pp. 727-731 ◽  
Author(s):  
Ali Bin Sarwar Zubairi ◽  
Farah Idrees ◽  
Kauser Jabeen ◽  
Saima Kamal ◽  
Afia Zafar
Keyword(s):  
Aspergillus Flavus ◽  
Competent Patient ◽  
Pulmonary Renal Syndrome ◽  
Lichtheimia Corymbifera

The chronically ischemic lower limb

JAMA ◽  
1966 ◽  
Vol 197 (11) ◽  
pp. 915-916
Author(s):  
I. J. Schatz
Keyword(s):  
Lower Limb

Systemic aspergillosis caused by an aflatoxin-producing strain of Aspergillus flavus

1998 ◽  
Vol 36 (2) ◽  
pp. 107-112 ◽  
Author(s):  
T. MORI ◽  
M. MATSUMURA ◽  
K. YAMADA ◽  
S. IRIE ◽  
K. OSHIMI ◽  
...  
Keyword(s):  
Aspergillus Flavus

Cardiac troponin I in patients with acute upper and lower limb ischemia

VASA ◽  
2008 ◽  
Vol 37 (4) ◽  
pp. 327-332 ◽  
Author(s):  
Koutouzis ◽  
Sfyroeras ◽  
Moulakakis ◽  
Kontaras ◽  
Nikolaou ◽  
...  
Keyword(s):  
Upper Limb ◽  
Lower Limb ◽  
Cardiac Troponin ◽  
Cardiac Involvement ◽  
Troponin I ◽  
Limb Ischemia ◽  
Elevated Troponin ◽  
Troponin Elevation ◽  
Lower Limb Ischemia ◽  
Ischemia Group

Background: The aim of this study was to investigate the presence, etiology and clinical significance of elevated troponin I in patients with acute upper or lower limb ischemia. The high sensitivity and specificity of cardiac troponin for the diagnosis of myocardial cell damage suggested a significant role for troponin in the patients investigated for this condition. The initial enthusiasm for the diagnostic potential of troponin was limited by the discovery that elevated cardiac troponin levels are also observed in conditions other than acute myocardial infarction, even conditions without obvious cardiac involvement. Patients and Methods: 71 consecutive patients participated in this study. 31 (44%) of them were men and mean age was 75.4 ± 10.3 years (range 44–92 years). 60 (85%) patients had acute lower limb ischemia and the remaining (11; 15%) had acute upper limb ischemia. Serial creatine kinase (CK), isoenzyme MB (CK-MB) and troponin I measurements were performed in all patients. Results: 33 (46%) patients had elevated peak troponin I (> 0.2 ng/ml) levels, all from the lower limb ischemia group (33/60 vs. 0/11 from the acute upper limb ischemia group; p = 0.04). Patients with lower limb ischemia had higher peak troponin I values than patients with upper limb ischemia (0.97 ± 2.3 [range 0.01–12.1] ng/ml vs. 0.04 ± 0.04 [0.01–0.14] ng/ml respectively; p = 0.003), higher peak CK values (2504 ± 7409 [range 42–45 940] U/ml vs. 340 ± 775 [range 34–2403] U/ml, p = 0.002, respectively, in the two groups) and peak CK-MB values (59.4 ± 84.5 [range 12–480] U/ml vs. 21.2 ± 9.1 [range 12–39] U/ml, respectively, in the two groups; p = 0.04). Peak cardiac troponin I levels were correlated with peak CK and CK-MB values. Conclusions: Patients with lower limb ischemia often have elevated troponin I without a primary cardiac source; this was not observed in patients presenting with acute upper limb ischemia. It is very important for these critically ill patients to focus on the main problem of acute limb ischemia and to attempt to treat the patient rather than the troponin elevation per se. Cardiac troponin elevation should not prevent physicians from providing immediate treatment for limb ischaemia to these patients, espescially when signs, symptoms and electrocardiographic findings preclude acute cardiac involvement.

Acute limb ischemia in a patient with pre-fibrotic myelofibrosis complicated by heparin-induced thrombocytopenia and thrombosis – case report and systematic review of dabigatran use

VASA ◽  
2020 ◽  
pp. 1-6 ◽  
Author(s):  
Marina Di Pilla ◽  
Stefano Barco ◽  
Clara Sacco ◽  
Giovanni Barosi ◽  
Corrado Lodigiani
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Lower Limb ◽  
Limb Ischemia ◽  
Acute Limb Ischemia ◽  
Review Of The Literature ◽  
Heparin Induced Thrombocytopenia ◽  
Lower Limb Ischemia ◽  
Vein Thrombosis ◽  
Left Lower Limb

Summary: A 49-year-old man was diagnosed with pre-fibrotic myelofibrosis after acute left lower-limb ischemia requiring amputation and portal vein thrombosis. After surgery he developed heparin-induced thrombocytopenia (HIT) with venous thromboembolism, successfully treated with argatroban followed by dabigatran. Our systematic review of the literature supports the use of dabigatran for suspected HIT.

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