scholarly journals Patient Outcomes With Use of Computed Tomography Angiography in Acute Ischemic Stroke and Transient Ischemic Attack: A Systematic Review and Meta-Analysis

Cureus ◽  
2020 ◽  
Author(s):  
Siying (Shari) Li ◽  
Aleksandar Trajkovski ◽  
Michael Siarkowski ◽  
Calvin Santiago ◽  
Kevin A Eng ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Systematic Review ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Patient Outcomes ◽  
Transient Ischemic Attack ◽  
Computed Tomography Angiography ◽  
Meta Analysis ◽  
Ischemic Attack

scholarly journals Cardiac imaging in ischemic stroke or transient ischemic attack of undetermined cause: Systematic review & meta-analysis

2021 ◽  
Author(s):  
Gerlinde van der Maten ◽  
Saskia Dijkstra ◽  
Matthijs F.L. Meijs ◽  
Clemens von Birgelen ◽  
Job van der Palen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ischemic Stroke ◽  
Cardiac Imaging ◽  
Transient Ischemic Attack ◽  
Meta Analysis ◽  
Ischemic Attack

scholarly journals Intraluminal Thrombi in the Cervico-Cephalic Arteries

Stroke ◽  
2019 ◽  
Vol 50 (2) ◽  
pp. 357-364 ◽  
Author(s):  
Ravinder-Jeet Singh ◽  
Debabrata Chakraborty ◽  
Sadanand Dey ◽  
Aravind Ganesh ◽  
Abdulaziz Sulaiman Al Sultan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ischemic Stroke ◽  
Functional Outcome ◽  
Scale Score ◽  
Transient Ischemic Attack ◽  
Computed Tomography Angiography ◽  
Functional Independence ◽  
Stroke Recurrence ◽  
Modified Rankin Scale ◽  
Ischemic Attack

Background and Purpose— Intraluminal thrombus (ILT) is an uncommon finding among patients with ischemic stroke. We report clinical-imaging manifestations, treatment offered, and outcome among patients with ischemic stroke/transient ischemic attack and ILT in their cervico-cephalic arteries. Methods— Sixty-one of 3750 consecutive patients with acute ischemic stroke/transient ischemic attack (within 24 hours of onset) and ILT on initial arch-to-vertex computed tomography angiography from April 2015 through September 2017 constituted the prospective study cohort. Functional outcome was assessed using the modified Rankin Scale score with functional independence at discharge defined as modified Rankin Scale score ≤2. Results— Prevalence of ILT on computed tomography angiography was 1.6% (95% CI, 1.2%–2.1%). Median age was 67 years (interquartile range, 56–73), and 40 subjects (65%) were male. The initial clinical presentation included transient ischemic attack in 12 (20%) and stroke in 49 patients (80%); most strokes (76%) were mild (National Institutes of Health Stroke Scale ≤5). The most common ILT location was cervical carotid or vertebral artery (n=48 [79%]) followed by intracranial (n=11 [18%]) and tandem lesions (n=2 [3%]). The most common initial treatment strategy was combination antithrombotics (heparin with single antiplatelet agent) among 57 patients (93%). Follow-up computed tomography angiography (n=59), after a median 6 days (interquartile range 4–10 days), revealed thrombus resolution in 44 patients (75% [completely in 27%]). Twenty four of 30 patients (80%) with >50% residual carotid stenosis underwent carotid revascularization (endarterectomy in 15 and stenting in 9 patients) without peri-procedural complications a median of 9 days after symptom onset. In-hospital stroke recurrence occurred in 4 patients (6.6%). Functional independence was achieved in 46 patients (75%) at discharge. Conclusions— Patients presenting with acute stroke/transient ischemic attack with ILT on baseline imaging have a favorable clinical course in hospital with low stroke recurrence, high rate of thrombus resolution, and good functional outcome when treated with combination antithrombotic therapy.

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