scholarly journals Acute Necrotizing Encephalitis in Viral Respiratory Tract Infection: An Autopsy Case Report

Cureus ◽  
2020 ◽  
Author(s):  
George S Stoyanov ◽  
Emran Lyutfi ◽  
Deyan L Dzhenkov ◽  
Lilyana Petkova
Keyword(s):  
Case Report ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Autopsy Case ◽  
Viral Respiratory Tract Infection ◽  
Acute Necrotizing ◽  
Viral Respiratory

Eustachian Tube Histopathology during Experimental Influenza a Virus Infection in the Chinchilla

1987 ◽  
Vol 96 (2) ◽  
pp. 199-206 ◽  
Author(s):  
G. Scott Giebink ◽  
Mary Lou Ripley ◽  
Peter F. Wright
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Influenza A Virus ◽  
Middle Ear ◽  
Influenza A ◽  
Middle Ear Pressure ◽  
Viral Respiratory Tract Infection ◽  
Pathologic Basis ◽  
Viral Respiratory

The eustachian tubes of 29 influenza a virus–infected chinchillas were examined for histopathologic signs at intervals up to 21 days after inoculation to elucidate the pathologic basis of negative middle ear pressure, which occurs during viral respiratory tract infection in humans. In the animal model, eardrum inflammation and negative middle ear pressure mirrored epithelial damage in the eustachian tube and the accumulation of cellular and mucous debris in the tubal lumen. Epithelial damage was greatest in the proximal two thirds of the tube near the nasopharynx, whereas goblet cell metaplasia and increased secretory activity was greatest in the distal, tympanic one third of the tube. These results provide a morphologic correlate to the development of negative middle ear pressure, and perhaps explain the pathologic basis for purulent otitis media during viral respiratory tract infection.

scholarly journals Airway CD8+T Cells Are Associated with Lung Injury during Infant Viral Respiratory Tract Infection

2016 ◽  
Vol 54 (6) ◽  
pp. 822-830 ◽  
Author(s):  
Thomas J. Connors ◽  
Thyyar M. Ravindranath ◽  
Kara L. Bickham ◽  
Claire L. Gordon ◽  
Feifan Zhang ◽  
...  
Keyword(s):  
T Cells ◽  
Tract Infection ◽  
Lung Injury ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Cd8 T Cells ◽  
Viral Respiratory Tract Infection ◽  
Viral Respiratory

scholarly journals Host response to mechanical ventilation for viral respiratory tract infection

2012 ◽  
Vol 40 (6) ◽  
pp. 1508-1515 ◽  
Author(s):  
Marije P. Hennus ◽  
Riny Janssen ◽  
Jeroen L.A. Pennings ◽  
Hennie M. Hodemaekers ◽  
Debby Kruijsen ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Host Response ◽  
Viral Respiratory Tract Infection ◽  
Viral Respiratory

Effect of viral respiratory tract infection on outcome of acute otitis media

1992 ◽  
Vol 120 (6) ◽  
pp. 856-862 ◽  
Author(s):  
Tasnee Chonmaitree ◽  
Mary J. Owen ◽  
Janak A. Patel ◽  
Dawn Hedgpeth ◽  
David Horlick ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Otitis Media ◽  
Acute Otitis Media ◽  
Viral Respiratory Tract Infection ◽  
Viral Respiratory

scholarly journals A curated transcriptome dataset collection to investigate the blood transcriptional response to viral respiratory tract infection and vaccination.

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 284 ◽  
Author(s):  
Salim Bougarn ◽  
Sabri Boughorbel ◽  
Damien Chaussabel ◽  
Nico Marr
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Respiratory Tract Infections ◽  
Respiratory Viruses ◽  
Immune Defense ◽  
Correlates Of Protection ◽  
Viral Respiratory Tract Infection ◽  
Tract Infections ◽  
Viral Respiratory

The human immune defense mechanisms and factors associated with good versus poor health outcomes following viral respiratory tract infections (VRTI), as well as correlates of protection following vaccination against respiratory viruses, remain incompletely understood. To shed further light into these mechanisms, a number of systems-scale studies have been conducted to measure transcriptional changes in blood leukocytes of either naturally or experimentally infected individuals, or in individual’s post-vaccination. Here we are making available a public repository, for research investigators for interpretation, a collection of transcriptome datasets obtained from human whole blood and peripheral blood mononuclear cells (PBMC) to investigate the transcriptional responses following viral respiratory tract infection or vaccination against respiratory viruses. In total, Thirty one31 datasets, associated to viral respiratory tract infections and their related vaccination studies, were identified and retrieved from the NCBI Gene Expression Omnibus (GEO) and loaded in a custom web application designed for interactive query and visualization of integrated large-scale data. Quality control checks, using relevant biological markers, were performed. Multiple sample groupings and rank lists were created to facilitate dataset query and interpretation. Via this interface, users can generate web links to customized graphical views, which may be subsequently inserted into manuscripts to report novel findings. The GXB tool enables browsing of a single gene across projects, providing new perspectives on the role of a given molecule across biological systems in the diagnostic and prognostic following VRTI but also in identifying new correlates of protection. This dataset collection is available at: http://vri1.gxbsidra.org/dm3/geneBrowser/list.

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