scholarly journals A Curious Case of Crystal Deposit Disease in the Petrous Bone

Cureus ◽  
2019 ◽  
Author(s):  
Marije De Jong ◽  
Carlos Candanedo ◽  
Tal Keidar Haran ◽  
Michal Kaufman
Keyword(s):  
Petrous Bone ◽  
Crystal Deposit

Primary Cholesteatoma of Petrous Bone: A Case Report

2014 ◽  
Vol 75 (S 02) ◽  
Author(s):  
Insaf Zgolli ◽  
S. Mezri ◽  
I. Kasraoui ◽  
N. Moussa ◽  
K. Akkari ◽  
...  
Keyword(s):  
Case Report ◽  
Petrous Bone

Mechatronical Assistance in the Surgery of Petrous Bone: First Experiences with a Navigation-Controlled Drill

Skull Base ◽  
2007 ◽  
Vol 16 (S 1) ◽  
Author(s):  
Gero Strauss ◽  
Kirill Koulechov ◽  
Mathias Hofer ◽  
Andreas Dietz ◽  
Christos Trantakis ◽  
...  
Keyword(s):  
Petrous Bone

Petrous Bone Meningiomas

Skull Base ◽  
2007 ◽  
Vol 17 (S 1) ◽  
Author(s):  
F. Calbucci
Keyword(s):  
Petrous Bone

Petrous bone lesions: surgical implementation and outcomes of extradural subtemporal approach

2021 ◽  
Author(s):  
Udom Bawornvaraporn ◽  
Ali R. Zomorodi ◽  
Allan H. Friedman ◽  
Takanori Fukushima
Keyword(s):  
Petrous Bone ◽  
Bone Lesions ◽  
Subtemporal Approach

scholarly journals POS0132 IS THE INTERCRITICAL GOUT REALLY ASYMPTOMATIC? THE INFLAMMATORY ROLE OF THE SILENT URATE CRYSTAL DEPOSITION

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 277.1-278
Author(s):  
C. Diaz-Torne ◽  
M. A. Ortiz ◽  
S. Jeria Navarro ◽  
A. Garcia-Gullien ◽  
L. Sainz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Whole Body ◽  
Subclinical Inflammation ◽  
Monosodium Urate ◽  
Crystal Deposition ◽  
Secretome Analysis ◽  
Healthy Donors ◽  
Cytokine Levels ◽  
Urate Crystal ◽  
Crystal Deposit

Background:Gout is the most prevalent inflammatory arthritis. Gout is chronic inflammatory deposition disease related to an increase of cardiovascular (CV) events and mortality. Subclinical chronic inflammation has been demonstrated in this patients but not its relation with the monosodium urate (MSU) crystal deposit size and the number of CV risk factors.Objectives:To study the subclinical inflammation in intercritical gout patients and its possible relation to the estimated size of the crystal deposition and the number of CV risk factors.Methods:To analyze subclinical inflammation we performed a secretome analysis and a cytokine and adiponektine plasma levels quantification (IL-1β, IL-18, IL-6, sIL-6R, TNFα, CXCL-5, RANTES, leptin, resistin and adiponectin) in a cohort of gout patients. As nowadays it is not feasible to determinate the whole body deposit of MSU crystals we created three different MSU crystal deposit size patient groups using an indirect clinical and analytical classification to estimate it. Then we compared cytokine levels between healthy donors and gout patients. We also compared cytokine levels between the different crystal size deposition groups and studied its association to the number of CV risk factors.Results:Ninety consecutive patients attending a Crystal Arthritis Unit were studied. Mean age was 68.27 (28-101) years. 81.1% were male. Clinical gout evolution was of 10.1±9.8 years. 77.5% were on urate lowering treatment. 24% had tophaceous gout. Mean uric acid was 6.3±2.1 mg/dl with 47.1% of them being on target. Hypertension was present in 68.9%, diabetes mellitus in 18.9%, dislipemia in 48.9%, BMI>30 in 32.9%, abdominal obesity in 50% and 16.1% suffered from ischemic heart disease. From the 102 molecules studied in the secretome analysis in 56 there was at least a 20% difference between donors group and any of the deposition groups. In 74% of them gout patients secreted lower levels. IL-18, sIL-6R, RANTES, leptin and adiponectin were higher in patients than in healthy donors. IL-18, sIL6-R, RANTES and CXCL5 levels were associated to the size of the crystal deposits. IL-18, sIL-6R, RANTES and leptin were higher in gout groups with CV risk factors. IL-18, sIL6-R, RANTES and leptin were higher in gout patients with no risk factors when compared to healthy donors with no risk factors. We found no differences when comparing urate lowering treated and non-treated patients.Conclusion:Our results demonstrate that some proinflammatory cytokines and metabolic proteins are raised in intercritical gout patients. Some of them are different from the flare/inflammasome expected ones. In some cytokines this elevation is related to the size of the monosodium urate crystal deposit and/or to the number of cardiovascular risk factors. This cytokine changes could help to explain the increase of the cardiovascular events in gout patients.Disclosure of Interests:Cesar Diaz-Torne Grant/research support from: Received a grant from Grünenthal, Maria Angels Ortiz: None declared, Sicylle Jeria Navarro: None declared, Andrea Garcia-Gullien: None declared, Lluis Sainz: None declared, Hector Corominas: None declared, Silvia Vidal: None declared

En bloc petrosectomy using a Gigli saw for petroclival lesions

1995 ◽  
Vol 83 (3) ◽  
pp. 559-560 ◽  
Author(s):  
Tomio Sasaki ◽  
Makoto Taniguchi ◽  
Ichiro Suzuki ◽  
Takaaki Kirino
Keyword(s):  
Facial Nerve ◽  
Semicircular Canals ◽  
Petrous Bone ◽  
New Technique ◽  
En Bloc ◽  
Content Type ◽  
A New Technique ◽  
Transtentorial Approach ◽  
Fine Print

✓ The authors report a new technique for en bloc petrosectomy using a Gigli saw as an alternative to drilling the petrous bone in the combined supra- and infratentorial approach or the transpetrosal—transtentorial approach. It is simple and easy and avoids postoperative cosmetic deformity. This technique has been performed in 11 petroclival lesions without injuring the semicircular canals, the cochlea, or the facial nerve.

scholarly journals Insidious onset of headache, diplopia and Horner’s syndrome: a rare case of petrous bone osteomyelitis

2019 ◽  
Vol 12 (9) ◽  
pp. e231062
Author(s):  
Simon Biart ◽  
Janki Panicker
Keyword(s):  
Skull Base ◽  
Inflammatory Markers ◽  
Unusual Case ◽  
Petrous Bone ◽  
Skull Base Osteomyelitis ◽  
Unilateral Headache ◽  
Gradual Onset ◽  
Insidious Onset ◽  
Signal Change ◽  
Sixth Nerve

We present an unusual case of skull base osteomyelitis in an 88-year-old woman. She presented with gradual onset unilateral headache and diplopia. On examination, there was evidence of a left-sided Horner’s and ipsilateral sixth nerve palsy. In addition to persistent raised inflammatory markers, an MRI neck identified signal change in the petrous bone confirming a diagnosis of skull base osteomyelitis. Skull base osteomyelitis should be considered in presentations of subacute raised inflammatory markers in the context of ipsilateral cranial nerve signs.

scholarly journals The remnant of primary head sinus found in the case of dural arteriovenous fistula: A case report

2016 ◽  
Vol 22 (4) ◽  
pp. 452-456 ◽  
Author(s):  
Katsuhiro Mizutani ◽  
Takenori Akiyama ◽  
Kazunari Yoshida
Keyword(s):  
Arteriovenous Fistula ◽  
Dural Arteriovenous Fistula ◽  
Rare Condition ◽  
Venous Drainage ◽  
Petrous Bone ◽  
Jugular Bulb ◽  
Cone Beam ◽  
Middle Fossa ◽  
Rotational Angiography ◽  
Anatomic Information

In the embryo, the primary head sinus (PHS) is the first venous drainage channel in the craniocervical region. During embryonic development, this channel regresses and usually disappears completely; accordingly, a remnant of the PHS is an extremely rare condition and has been described in only a few previous studies. Here, we report a case of remnant of the PHS with a dural arteriovenous fistula (dAVF) in an adult. The remnant of the PHS had penetrated the petrous bone to run from the middle fossa to the jugular bulb and served as a drain for the middle fossa dAVF. We used digital subtraction angiography and reconstructed cone-beam computed tomography in 3D rotational angiography to obtain detailed anatomic information about the remnant PHS and additionally scrutinised and discussed its features.

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