scholarly journals A Comparative Study: Has MRI-guided Fusion Prostate Biopsy Changed the Prostate-specific Antigen Gray-zone Range?

Cureus ◽  
2019 ◽  
Author(s):  
Gökhan Sönmez ◽  
Şevket T Tombul ◽  
Türev Demirtaş ◽  
Figen Öztürk ◽  
Abdullah Demirtaş
2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Michael Maddox ◽  
Joseph Renzulli ◽  
Dragan Golijanin ◽  
Sammy Elsamra ◽  
Matthew Somerville ◽  
...  

2019 ◽  
Vol 13 (2) ◽  
pp. 59-68 ◽  
Author(s):  
Mustafa Zafer Temiz ◽  
Omer Onur Cakir ◽  
Serdar Aykan ◽  
Suat Hayri Kucuk ◽  
Necip Ozan Tiryakioglu ◽  
...  

2014 ◽  
Vol 8 (7-8) ◽  
pp. 476
Author(s):  
Olivier P. Heimrath ◽  
Zuzana Kos ◽  
Eric C. Belanger ◽  
Ilias Cagiannos ◽  
Chris Morash ◽  
...  

Introduction: We review a subset of men who had discordant prostate biopsy sums and were treated with radical prostatectomy.Methods: Consecutive patients treated with radical prostatectomy at The Ottawa Hospital between 2000 and 2012 were reviewed. Those with at least 1 prostate biopsy core of Gleason sum ≥8 and at least 1 prostate biopsy core of Gleason sum ≤7 cancer were included.Results: Of the 764 radical prostatectomies, 661 (87%) were eligible for the study and 35 (5%) met inclusion criteria. Of these, only 16 (46%) had prostatectomy Gleason sum of ≥8. When the highest biopsy core was Gleason sum 8 (n = 24), only 7 (29%) had a prostatectomy Gleason sum ≥8. When the highest biopsy core was Gleason 9 (n = 11), 9 (82%) had a prostatectomy Gleason sum ≥8 (relative risk [RR] 2.8; p = 0.004). Patients with clinical T3 tumours were at higher risk of Gleason sum ≥8 compared to cT1 patients (RR 3.7; p = 0.008). Patient age (p = 0.89), preoperative prostate-specific antigen (p = 0.34), prostate volume (p = 0.86), number of biopsy cores (p = 0.18), and proportion of biopsy cores with cancer (p = 0.96) were not strongly associated with risk of prostatectomy Gleason sum ≥8.Conclusion: These data should be considered when assigning patients into prognostic risk categories based on prostate biopsy information. Further study to verify our findings using larger samples is warranted.


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