scholarly journals Inverted Sinonasal Papilloma Involving the Middle Ear with Evidence of Squamous Cell Carcinoma

Cureus ◽  
2019 ◽  
Author(s):  
Fatima Alghamdi ◽  
Nora Aldohan ◽  
Sarah Al-Otaibi ◽  
Mohammad Dababo ◽  
Eyas O Othman
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Middle Ear ◽  
Squamous Cell ◽  
Sinonasal Papilloma

Squamous cell carcinoma and consequent otitis in a long-eared hedgehog ( Hemiechinus auritus ) — Case report

2009 ◽  
Vol 57 (1) ◽  
pp. 69-73
Author(s):  
János Gál ◽  
Krisztina Landauer ◽  
Elena Palade ◽  
Katalin Ivaskevics ◽  
Miklós Rusvai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Bacterial Infection ◽  
Cell Carcinoma ◽  
Middle Ear ◽  
Squamous Cell ◽  
Immunohistochemical Staining ◽  
Ear Canal ◽  
Affected Area ◽  
Staining Techniques

The authors describe a squamous cell carcinoma arising from the ear canal of a Long-eared Hedgehog ( Hemiechinus auritus ). No metastasis could be identified elsewhere in the animal. Due to the irritation caused by the tumorous proliferation the animal constantly scratched the affected area, which led to secondary bacterial infection of the middle ear accompanied by the stagnation of an increased volume of local secretions. Using routine haematoxylin and eosin and immunohistochemical staining techniques, the tumour was identified as a squamous cell carcinoma. This work constitutes the first description of such a tumour in a Long-eared Hedgehog.

Treatment Outcomes of Squamous Cell Carcinoma of External Auditory Canal and Middle Ear

2009 ◽  
Vol 75 (3) ◽  
pp. S424
Author(s):  
K. Yoshida ◽  
R. Sasaki ◽  
M. Nakabayashi ◽  
H. Nishimura ◽  
Y. Okamoto ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Treatment Outcomes ◽  
Middle Ear ◽  
Squamous Cell ◽  
External Auditory Canal

scholarly journals MON-260 Sinonasal Papilloma Masquerading as a Pituitary Macroadenoma

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Melissa Cohen ◽  
John Wilson ◽  
Daniel Joseph Toft
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Medical Attention ◽  
Total Testosterone ◽  
Invasive Squamous Cell Carcinoma ◽  
Sellar Mass ◽  
Pituitary Mass ◽  
Prepontine Cistern ◽  
Sinonasal Papilloma

Abstract Background: Sinonasal tumors are rare, with annual worldwide incidence of approximately 1 in 100,000, and are not commonly considered in the differential diagnosis of pituitary tumors (1). Sinonasal tumors are well known for their invasiveness, tendency to recur and association with malignancy. We present a case of sinonasal papilloma presenting as a large suprasellar mass. Clinical Case: A 61 year-old male with a past medical history including type 2 diabetes mellitus presented with chief complaints of headaches and visual disturbances over the past 6 months. Prior to admission he experienced episodes of left eye midline deviation associated with diplopia. New onset dysphagia associated with leftward tongue deviation prompted him to seek medical attention. The social history was notable for chemical exposures in his work at a hair salon; he is sexually active with his husband. He has had no sexually transmitted infections and has been vaccinated against human papilloma virus (HPV). CT of the brain showed a large sellar mass. A subsequent MRI of the pituitary demonstrated a large destructive mass centered on the clivus elevating the pituitary gland into the suprasellar cistern. The mass measured 6 cm x 4.5 cm in the axial plane with displacement without invasion of the cavernous sinuses. The mass extended anteriorly into the ethmoid sinuses and extended posteriorly into the prepontine cistern displacing the basilar artery. Pituitary hormonal analysis included a 250 mcg Cosyntropin stimulation test resulting with a random cortisol of <1.0 ug/dl rising to 17.7 ug/dl following Cosyntropin administration. Additional anterior pituitary results included FSH of 3.8 mIU/ml (1.5-14 mIU/ml), LH of 1.3 mIU/ml (1.4-7.7 mIU/ml), total testosterone of 230 ng/dl (300-700 ng/dl), and prolactin 11.1 ng/ml (2.6-13 ng/ml). Ophthalmology was consulted for visual field testing which proved normal, however a partial left cranial nerve VI palsy was noted likely secondary to cavernous sinus involvement. A biopsy of the sellar mass was obtained by bedside nasal endoscopy. The initial biopsy was consistent with a non-dysplastic, inverted sinonasal papilloma with negative HPV and P16 serologies. The patient underwent resection of the pituitary mass, with surgical pathology showing superficially invasive squamous cell carcinoma arising from sinonasal papilloma. Conclusion: This is one of the very few cases reported in the literature of a sinonasal papilloma masquerading as a pituitary mass. Sinonasal papilloma should be considered when evaluating large destructive suprasellar tumors. Although a benign tumor, the local aggressiveness of sinonasal papilloma and the potential to give rise to squamous cell carcinoma highlights the significance of identifying this lesion.

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