scholarly journals Cerebral Venous Sinus Thrombosis with Bilateral Abducens Palsy in a Patient with Heterozygous Prothrombin G20210A Mutation

Cureus ◽  
2019 ◽  
Author(s):  
Soujanya Sodavarapu ◽  
Saiyed W Ali ◽  
Megha Goyal
Keyword(s):  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Prothrombin G20210a ◽  
Abducens Palsy ◽  
Venous Sinus Thrombosis ◽  
G20210a Mutation ◽  
Bilateral Abducens Palsy ◽  
Bilateral Abducens

Cerebral venous sinus thrombosis: a complication of nitrous oxide abuse

2021 ◽  
Vol 14 (8) ◽  
pp. e244478
Author(s):  
Laura de Valck ◽  
Victoria Margarita Defelippe ◽  
Nathalia Anne Maria Geertruida Bouwman
Keyword(s):  
Nitrous Oxide ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Prothrombin G20210a ◽  
Vitamin B ◽  
Venous Sinus Thrombosis ◽  
Multiple Risk Factors ◽  
G20210a Mutation ◽  
Blurry Vision

Nitrous oxide (NO) is an inhalant that has become increasingly popular as a recreational drug. While it is presumed to be harmless, a number of adverse effects of NO have been described. We discuss the case of a 24-year-old man with no medical history, who initially presented to the emergency department with progressive polyneuropathy caused by vitamin B12 deficiency after NO abuse. Two days after being discharged with hydroxocobalamin supplementation, the patient returned with a severe headache, blurry vision and slurred speech. Imaging revealed cerebral venous sinus thrombosis. Hypercoagulability workup showed slightly elevated homocysteine and normalised vitamin B12 after supplementation. Genetic testing showed a heterozygous prothrombin G20210A mutation. He was treated with low-molecular-weight heparin followed by dabigatran. We hypothesise that NO use may increase the risk of developing cerebral venous thrombosis, especially in patients with multiple risk factors and elevated homocysteine levels.

scholarly journals Bilateral Abducens Nerve Palsy Due to Extensive Cerebral Venous Sinus Thrombosis

Medicina ◽  
2019 ◽  
Vol 55 (4) ◽  
pp. 115
Author(s):  
Buljan ◽  
Šarić ◽  
Czersky Hafner ◽  
Perković
Keyword(s):  
Nerve Palsy ◽  
Sinus Thrombosis ◽  
Rare Condition ◽  
Abducens Nerve ◽  
Positive Outcome ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Abducens Nerve Palsy ◽  
Venous Sinus Thrombosis ◽  
Bilateral Abducens

Cerebral venous sinus thrombosis (CVST) is a relatively rare condition. We present a case of an acute aseptic thrombosis of the sagittal, transverse and sigmoid sinus in a puerperium patient with protein S deficiency. The specifics of the case include high intracranial pressure (ICP) caused by sinus thrombosis with typical symptomatology and bilateral papilloedema, which also manifested in transient bilateral abducens nerve palsy and, consequently, bilateral horizontal diplopia. The recovery of the cranial nerve function occurred 3 to 4 weeks after it was initially reported. Prompt and adequate anticoagulant therapy contributed to the almost complete recanalization of the dural venous sinus thrombosis and a positive outcome of the disease.

An Unusual Cause of Cerebral Venous Sinus Thrombosis: Prothrombin G20210A Gene Mutation

2007 ◽  
Vol 100 (9) ◽  
pp. 906-908 ◽  
Author(s):  
Mateo Porres-Aguilar ◽  
Jaime H. Square ◽  
Raul Storey ◽  
Simon Rodriguez-Dunn ◽  
Mohamed S. Mohamed-Aly
Keyword(s):  
Gene Mutation ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Prothrombin G20210a ◽  
Venous Sinus Thrombosis

scholarly journals Abducens Palsy Due to Cerebral Venous Sinus Thrombosis in a Patient with Heart Failure

2015 ◽  
Vol 45 (4) ◽  
pp. 179-181
Author(s):  
Cem Özgönül ◽  
Osman Melih Ceylan ◽  
Fatih Mehmet Mutlu ◽  
Halil İbrahim Altınsoy ◽  
Mustafa Aparcı
Keyword(s):  
Heart Failure ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Abducens Palsy ◽  
Venous Sinus Thrombosis

Long-term prognosis of cerebral venous sinus thrombosis in childhood

2004 ◽  
Vol 46 (08) ◽  
Author(s):  
Els LLM De Schryver ◽  
Ingrid Blom ◽  
Kees PJ Braun ◽  
L Jaap Kappelle ◽  
Gabriël JE Rinkel ◽  
...  
Keyword(s):  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Long Term Prognosis
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