scholarly journals Acute Effects of Hypoxic Gas Admixtures on Pulmonary Blood Flow and Regional Oxygenation in Children Awaiting Norwood Palliation

Cureus ◽  
2019 ◽  
Author(s):  
Lisha Thomas ◽  
Saul Flores ◽  
Joshua Wong ◽  
Rohit Loomba
Keyword(s):  
Blood Flow ◽  
Pulmonary Blood Flow ◽  
Acute Effects ◽  
Gas Admixtures

Acute effects of partial compression of ductus arteriosus on fetal pulmonary circulation

1989 ◽  
Vol 257 (2) ◽  
pp. H626-H634 ◽  
Author(s):  
S. H. Abman ◽  
F. J. Accurso
Keyword(s):  
Blood Flow ◽  
Pulmonary Artery ◽  
Pulmonary Vascular Resistance ◽  
Pulmonary Artery Pressure ◽  
Pulmonary Circulation ◽  
Pulmonary Blood Flow ◽  
Ductus Arteriosus ◽  
Base Line ◽  
Acute Effects ◽  
Artery Pressure

To determine the acute effects of increased pulmonary artery pressure and flow on the fetal pulmonary circulation, we studied the response of pulmonary blood flow and vascular reactivity to partial compression of the ductus arteriosus in 22 chronically prepared late-gestation fetal lambs. An inflatable occluder was placed loosely around the ductus arteriosus for compression. Partial compression of the ductus rapidly increased mean pulmonary artery pressure from 45 +/- 1 to 60 +/- 1 mmHg (mean +/- SE) and left pulmonary artery blood flow from 65 +/- 6 to 151 +/- 11 ml/min at 30 min (P less than 0.001; 12 animals). Despite keeping pulmonary artery pressure constant, pulmonary blood flow steadily declined and by 2 h was not different from base-line values. Pulmonary vascular resistance initially fell during the first 30 min of partial compression but then steadily increased and remained elevated above base-line values for at least 30 min after the release of the occluder (P less than 0.001). The decline of pulmonary vascular resistance during the first 30 min of compression was blunted after treatment with the cyclooxygenase inhibitor, meclofenamate (P less than 0.001; 6 animals). Rapid incremental ductus compressions demonstrated a decrease in the slope of the pressure-flow relationship from 3.30 +/- 0.27 (control) to 1.59 +/- 0.21 ml.min-1.mmHg-1 during the postcompression period (P less than 0.001; 12 animals). The vasodilation response to small increases of fetal PO2 was markedly blunted during the postcompression period (P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

Noninvasive Investigation of Pulmonary Blood Flow in Children with Pulmonary Hypertension Using the TRV/RVOT VTI Ratio

2017 ◽  
Vol 65 (S 02) ◽  
pp. S111-S142
Author(s):  
M. Koestenberger ◽  
D. Baumgartner ◽  
G. Hansmann ◽  
S. Schweintzger ◽  
G. Grangl ◽  
...  
Keyword(s):  
Blood Flow ◽  
Pulmonary Hypertension ◽  
Pulmonary Blood Flow

Additional pulmonary blood flow in Glenn anastomosis has no adverse effect on outcome of later TCPC

2004 ◽  
Vol 52 (S 1) ◽  
Author(s):  
PA Berdat ◽  
A Serraf ◽  
E Belli ◽  
F Lacour-Gayet ◽  
C Planch� ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Blood Flow ◽  
Pulmonary Blood Flow
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