scholarly journals Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome

Cureus ◽  
2019 ◽  
Author(s):  
Mai-Lynn Bui ◽  
Jordan K Gould ◽  
Akshay Mentreddy ◽  
Emily Sigsbee ◽  
Hector Lalama
Keyword(s):  
Neuromyelitis Optica ◽  
Rare Case ◽  
Spectrum Disorder ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Isolated Brainstem

scholarly journals Neuromyelitis Optica Spectrum Disorder with Tumefactive Demyelination mimicking Multiple Sclerosis: A Rare Case

2016 ◽  
Vol 7 ◽  
Author(s):  
Ujjawal Roy ◽  
Dinesh Satyanarayan Saini ◽  
Koushik Pan ◽  
Alak Pandit ◽  
Goutam Ganguly ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Neuromyelitis Optica ◽  
Rare Case ◽  
Spectrum Disorder ◽  
Neuromyelitis Optica Spectrum Disorder

scholarly journals A rare case of short-lasting unilateral neuralgiform headache with conjunctival injection and tearing with progression to neuromyelitis optica spectrum disorder

2020 ◽  
Vol 48 (10) ◽  
pp. 030006052096434
Author(s):  
Lu Wang ◽  
Hong-jun Su ◽  
Guan-jie Song
Keyword(s):  
Neuromyelitis Optica ◽  
Rare Case ◽  
Visual Loss ◽  
Primary Headache ◽  
Spectrum Disorder ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Conjunctival Injection ◽  
Headache Syndrome ◽  
Underlying Diseases

Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a rare primary headache syndrome. However, some cases of secondary SUNCT are attributed to underlying diseases such as demyelination. We herein report a case of SUNCT with progression to neuromyelitis optica spectrum disorder (NMOSD). A 43-year-old woman developed headaches; 6 weeks later, she developed bilateral visual loss and numbness on the left side of her body. She was ultimately diagnosed with NMOSD.

scholarly journals Relapse of Neuromyelitis Optica Spectrum Disorder Presented with Suspected Bacterial Meningomyelitis

2020 ◽  
Vol 38 (2) ◽  
pp. 129-132
Author(s):  
Geun Soo Kim ◽  
Bo Young Kim ◽  
Pamela Song ◽  
Jae Jung Lee ◽  
Hong-Kyun Park ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Neuromyelitis Optica ◽  
Rare Case ◽  
Demyelinating Disease ◽  
Neurological Diseases ◽  
Spectrum Disorder ◽  
Aquaporin 4 ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Antecedent Infection ◽  
Csf Findings

Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory demyelinating disease. Anti-aquaporin-4 antibodies serve as a specific biomarker, while other factors including antecedent infection may also play a role in the development of NMOSD. Abnormal cerebrospinal fluid (CSF) findings such as leukocytosis with concentration >50/mm<sup>3</sup> are one of the characteristics of NMOSD, but these were not specific for identifying other infective neurological diseases. Here we describe a rare case of NMOSD with CSF findings suggestive of bacterial meningomyelitis.

scholarly journals Neuromyelitis optica spectrum disorder with deafness and an extensive brainstem lesion

Heliyon ◽  
2021 ◽  
Vol 7 (1) ◽  
pp. e06106
Author(s):  
Asako Onda ◽  
Mikihiro Yamazaki ◽  
Takashi Shimoyama ◽  
Hiroshi Yaguchi
Keyword(s):  
Neuromyelitis Optica ◽  
Spectrum Disorder ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Brainstem Lesion

Sleep disorders as a possible predisposing attack factor in neuromyelitis optica spectrum disorder (NMOSD): A case-control study

2021 ◽  
Vol 204 ◽  
pp. 106606
Author(s):  
Samaneh Haji Molla Rabi ◽  
Shaghayegh Shahmirzaei ◽  
Mohammad Ali Sahraian ◽  
Razieh Sadat Kazemi Mozdabadi ◽  
Hossein Rezaei Aliabadi ◽  
...  
Keyword(s):  
Sleep Disorders ◽  
Neuromyelitis Optica ◽  
Case Control Study ◽  
Case Control ◽  
Spectrum Disorder ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Control Study

scholarly journals The possible role of Interleukin-6 as a regulator of insulin sensitivity in patients with neuromyelitis optica spectrum disorder

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhila Maghbooli ◽  
Abdorreza Naser Moghadasi ◽  
Nasim Rezaeimanesh ◽  
Abolfazl Omidifar ◽  
Tarlan Varzandi ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Neuromyelitis Optica ◽  
Serum Levels ◽  
Spectrum Disorder ◽  
Control Group ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Downstream Signaling ◽  
Reduce Insulin Sensitivity ◽  
Circulating Levels

Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) is associated with inflammatory mediators that may also trigger downstream signaling pathways leading to reduce insulin sensitivity. Methods We aimed to determine the risk association of hyperinsulinemia in NMOSD patients with seropositive AQP4-IgG and the serum levels of interleukin (IL)-6 and IL-17A compared with the control group. Serum levels of metabolic (Insulin, Fasting Blood Sugar (FBS), lipid profile) and inflammatory (IL-6 and IL-17) markers were assessed in 56 NMOSD patients and 100 controls. Results Hyperinsulinemia was more prevalent in NMOSD patients independent of age, sex and body mass index (BMI) (48.2% vs. 26%, p = 0.005) compared to control group. After adjusting age, sex and BMI, there was significant association between lower insulin sensitivity (IS) and NMOSD risk (95% CI: Beta = 0.73, 0.62 to 0.86, p = 0.0001). Circulating levels of IL-6 and IL-17 were higher in NMOSD patients, and only IL-6 had an effect modifier for the association between lower insulin sensitivity and NMOSD risk. Conclusions Our data suggests that inflammatory pathogenesis of NMOSD leads to hyperinsulinemia and increases the risk of insulin resistance.

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