scholarly journals Large Coronary Arteries Mean No Chance of a Heart Attack, Right? An Acute Myocardial Infarction in the Setting of Holding Anticoagulation for a Routine Colonoscopy

Cureus ◽  
2019 ◽  
Author(s):  
Nathan Brewster ◽  
Jennifer Nesfeder ◽  
Ryan Murphy ◽  
Brian Holahan ◽  
Syed Rafay Ali Sabzwari
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Arteries ◽  
Heart Attack ◽  
Large Coronary Arteries

Studies on the Functionality of Newly Synthesized Fibrinogen after Treatment of Acute Myocardial Infarction with Streptokinase, Increase in the Rate of Fibrinopeptide Release

1993 ◽  
Vol 70 (06) ◽  
pp. 0978-0983 ◽  
Author(s):  
Edelmiro Regano ◽  
Virtudes Vila ◽  
Justo Aznar ◽  
Victoria Lacueva ◽  
Vicenta Martinez ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Molecular Weight ◽  
Steady State ◽  
High Molecular Weight ◽  
Coronary Arteries ◽  
Risk Index ◽  
Weight Fraction ◽  
High Molecular Weight Fraction ◽  
Fibrinopeptide A

SummaryIn 15 patients with acute myocardial infarction who received 1,500,000 U of streptokinase, the gradual appearance of newly synthesized fibrinogen and the fibrinopeptide release during the first 35 h after SK treatment were evaluated. At 5 h the fibrinogen circulating in plasma was observed as the high molecular weight fraction (HMW-Fg). The concentration of HMW-Fg increased continuously, and at 20 h reached values higher than those obtained from normal plasma. HMW-Fg represented about 95% of the total fibrinogen during the first 35 h. The degree of phosphorylation of patient fibrinogen increased from 30% before treatment to 65% during the first 5 h, and then slowly declined to 50% at 35 h.The early rates of fibrinopeptide A (FPA) and phosphorylated fibrinopeptide A (FPAp) release are higher in patient fibrinogen than in isolated normal HMW-Fg and normal fibrinogen after thrombin addition. The early rate of fibrinopeptide B (FPB) release is the same for the three fibrinogen groups. However, the late rate of FPB release is higher in patient fibrinogen than in normal HMW-Fg and normal fibrinogen. Therefore, the newly synthesized fibrinogen clots faster than fibrinogen in the normal steady state.In two of the 15 patients who had occluded coronary arteries after SK treatment the HMW-Fg and FPAp levels increased as compared with the 13 patients who had patent coronary arteries.These results provide some support for the idea that an increased synthesis of fibrinogen in circulation may result in a procoagulant tendency. If this is so, the HMW-Fg and FPAp content may serve as a risk index for thrombosis.

scholarly journals The protective effects of GLP-1 receptor agonist lixisenatide on oxygen-glucose deprivation/reperfusion (OGD/R)-induced deregulation of endothelial tube formation

RSC Advances ◽  
2020 ◽  
Vol 10 (17) ◽  
pp. 10245-10253 ◽  
Author(s):  
Mochao Xiao ◽  
Daifeng Lu ◽  
Jiali Tian ◽  
Yang Yu ◽  
Qin Zhang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Arteries ◽  
Receptor Agonist ◽  
Glucose Deprivation ◽  
Tube Formation ◽  
Oxygen Glucose Deprivation ◽  
Protective Effects ◽  
Endothelial Tube Formation

Acute myocardial infarction (AMI) is a complication of atherosclerosis that takes place in coronary arteries.

Multiple coronary thromboses in previously normal coronary arteries: a rare cause of acute myocardial infarction

1980 ◽  
Vol 99 (4) ◽  
pp. 506-509 ◽  
Author(s):  
Edward H. Schuster ◽  
Stephen C. Achuff ◽  
William R. Bell ◽  
Bernadine H. Bulkley
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Arteries ◽  
Normal Coronary Arteries

scholarly journals Trends in Prehospital Delay in Patients With Acute Myocardial Infarction (from the Worcester Heart Attack Study)

2008 ◽  
Vol 102 (12) ◽  
pp. 1589-1594 ◽  
Author(s):  
Jane S. Saczynski ◽  
Jorge Yarzebski ◽  
Darleen Lessard ◽  
Frederick A. Spencer ◽  
Jerry H. Gurwitz ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Heart Attack ◽  
Prehospital Delay
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