scholarly journals Hematological Profile of Patients Having Malaria-positive Peripheral Blood Smears: A Cross-sectional Study at a Diagnostic Research Center in Khyber Pakhtunkhwa, Pakistan

Cureus ◽  
2018 ◽  
Author(s):  
Inam Ullah ◽  
Muhammad U Ali ◽  
Saeed Ali ◽  
Ahmad Rafiq ◽  
Zeeshan Sattar ◽  
...  
2013 ◽  
Vol 53 (6) ◽  
pp. 295 ◽  
Author(s):  
Mahrani Lubis ◽  
Rusdidjas Rusdidjas ◽  
Rafita Ramayati ◽  
Oke Rina Ramayani ◽  
Rosmayanti S Siregar ◽  
...  

Background Malaria-induced proteinuria has been observed insevere cases of malaria. Few studies have been done to assess foran association between proteinuria and malaria parasite countsbefore the disease becomes severe.Objective To investigate a possible association between proteinuriaand malaria parasite counts in children .Methods A cross-sectional study was conducted on school-agedchildren in Panyabungan, Mandailing Natal, between Septemberto November 2010. Malaria was diagnosed by microscopicexamination of peripheral blood smears. Children with malariaunderwent proteinuria t ests by urine dipstick method. Anassociation between proteinuria and malaria parasite counts wasanalyzed using linear regression test.Results Of 181 participants with Plasmodium fak:iparum malaria,53.6% were female and had a mean age of 7.8 years. Subjects'nutritional status were as follows: 50.8% normoweight, 28.2%mild malnutrition, 3 .3% moderate malnutrition, and 17. 7% severemalnutrition. Clinical manifestations showed 36.5% suffered fromsubfebrile temperatures and 29.8% had pallor. Proteinuria occurredin 45.9% participants and there was a weak association betweenproteinuria and malaria parasite counts (raa .261, Paa .0001).Conclusion There is a weak association between proteinuria andmalaria parasite counts in children.


2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Solomon Dhliwayo ◽  
Brighton Chihambakwe ◽  
Knowledge Taonezvi ◽  
Silvester M. Chikerema ◽  
Musavengana T. Tivapasi ◽  
...  

A cross-sectional study was done to determine ehrlichiosis seroprevalence and babesiosis prevalence in dogs that were presented to selected veterinary clinics in Harare. Sera from randomly selected dogs were tested for antibodies to Ehrlichia spp. using an enzyme-linked immunosorbent assay while microscopy of peripheral blood smears was used to confirm babesiosis. Overall, 75.2% (88/117, 95% CI: 66.2–82.5) of sera samples tested were positive to Ehrlichia spp. antibodies while the prevalence of canine babesiosis was 47.9% (56/117, 95% CI: 38.6–57.3). Age, breed, and sex were found not to be associated with the two disease conditions p>0.05. Most of the dogs with babesiosis (82.1%, 46/56) were also positive to Ehrlichia spp. antibodies. Hypoalbuminaemia (53.8%, 63/117), anaemia (53.0%, 62/117) and thrombocytopaenia (40.2%, 47/117) were the most common laboratory findings. Thrombocytopaenia and hypoalbuminaemia was more pronounced in dogs with babesiosis only while anaemia was more marked in dogs with babesiosis and positive to Ehrlichia spp. antibodies.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xingrui Wang ◽  
Qinglin Che ◽  
Xiaoxiao Ji ◽  
Xinyi Meng ◽  
Lang Zhang ◽  
...  

Abstract Background Coronavirus disease 2019 (COVID-19) has caused a global pandemic that has raised worldwide concern. This study aims to investigate the correlation between the extent of lung infection and relevant clinical laboratory testing indicators in COVID-19 and to analyse its underlying mechanism. Methods Chest high-resolution computer tomography (CT) images and laboratory examination data of 31 patients with COVID-19 were extracted, and the lesion areas in CT images were quantitatively segmented and calculated using a deep learning (DL) system. A cross-sectional study method was carried out to explore the differences among the proportions of lung lobe infection and to correlate the percentage of infection (POI) of the whole lung in all patients with clinical laboratory examination values. Results No significant difference in the proportion of infection was noted among various lung lobes (P > 0.05). The POI of total lung was negatively correlated with the peripheral blood lymphocyte percentage (L%) (r = − 0.633, P < 0.001) and lymphocyte (LY) count (r = − 0.555, P = 0.001) but positively correlated with the neutrophil percentage (N%) (r = 0.565, P = 0.001). Otherwise, the POI was not significantly correlated with the peripheral blood white blood cell (WBC) count, monocyte percentage (M%) or haemoglobin (HGB) content. In some patients, as the infection progressed, the L% and LY count decreased progressively accompanied by a continuous increase in the N%. Conclusions Lung lesions in COVID-19 patients are significantly correlated with the peripheral blood lymphocyte and neutrophil levels, both of which could serve as prognostic indicators that provide warning implications, and contribute to clinical interventions in patients.


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