scholarly journals An Approach to Improve Accuracy of Optical Tracking Systems in Cranial Radiation Therapy

Cureus ◽  
2015 ◽  
Author(s):  
Patrick Stüber ◽  
Benjamin Wagner ◽  
Tobias Wissel ◽  
Ralf Bruder ◽  
Achim Schweikard ◽  
...  
2019 ◽  
Vol 24 (6) ◽  
pp. 680-688
Author(s):  
David S. Hersh ◽  
Kenneth Moore ◽  
Vincent Nguyen ◽  
Lucas Elijovich ◽  
Asim F. Choudhri ◽  
...  

OBJECTIVEStenoocclusive cerebral vasculopathy is an infrequent delayed complication of ionizing radiation. It has been well described with photon-based radiation therapy but less so following proton-beam radiotherapy. The authors report their recent institutional experience in evaluating and treating children with radiation-induced cerebral vasculopathy.METHODSEligible patients were age 21 years or younger who had a history of cranial radiation and subsequently developed vascular narrowing detected by MR arteriography that was significant enough to warrant cerebral angiography, with or without ischemic symptoms. The study period was January 2011 to March 2019.RESULTSThirty-one patients met the study inclusion criteria. Their median age was 12 years, and 18 (58%) were male. Proton-beam radiation therapy was used in 20 patients (64.5%) and photon-based radiation therapy was used in 11 patients (35.5%). Patients were most commonly referred for workup as a result of incidental findings on surveillance tumor imaging (n = 23; 74.2%). Proton-beam patients had a shorter median time from radiotherapy to catheter angiography (24.1 months [IQR 16.8–35.4 months]) than patients who underwent photon-based radiation therapy (48.2 months [IQR 26.6–61.1 months]; p = 0.04). Eighteen hemispheres were revascularized in 15 patients. One surgical patient suffered a contralateral hemispheric infarct 2 weeks after revascularization; no child treated medically (aspirin) has had a stroke to date. The median follow-up duration was 29.2 months (IQR 21.8–54.0 months) from the date of the first catheter angiogram to last clinic visit.CONCLUSIONSAll children who receive cranial radiation therapy from any source, particularly if the parasellar region was involved and the child was young at the time of treatment, require close surveillance for the development of vasculopathy. A structured and detailed evaluation is necessary to determine optimal treatment.


Epilepsia ◽  
1999 ◽  
Vol 40 (3) ◽  
pp. 341-344 ◽  
Author(s):  
Harvey J. Mamon ◽  
Patrick Y. Wen ◽  
Anne C. Burns ◽  
Jay S. Loeffler

1994 ◽  
Author(s):  
Gillian K. Groves ◽  
Kim M. Chacon ◽  
Kenneth E. Prager ◽  
Larisa Stephan

2017 ◽  
Vol 8 (1) ◽  
pp. 10
Author(s):  
Bert De Coninck ◽  
Jan Victor ◽  
Patrick De Baets ◽  
Stijn Herregodts ◽  
Matthias Verstraete

The use of mechanical pointers in optical tracking systems is needed to aid registration processes of unlocated rigid bodies. Error on the target point of a pointer can cause wrong positioning of vital objects and as such these errors have to be avoided. In this paper, the different errors that originate during this process are described, after which this error analysis is used for the optimisation of an improved pointer design. The final design contains six coplanar fiducials, favored by its robustness and low error. This configuration of fiducials is then analysed theoretically as well as practically to understand how it is performing. The error on tracking the target point of the pointer is found with simulation to be around 0.7 times the error of measuring one fiducial in space. However, practically this error is about equal to the fiducial tracking error, due to the non-normally distributed errors on each separate fiducial.


2016 ◽  
Vol 24 (2) ◽  
pp. 335-342
Author(s):  
彭树萍 PENG Shu-ping ◽  
李 博 LI Bo ◽  
姜润强 JIANG Run-qiang ◽  
陈长青 CHEN Chang-qing ◽  
于洪君 YU Hong-jun

2018 ◽  
Vol 33 (5) ◽  
pp. 359-366 ◽  
Author(s):  
Matthew Nordstrom ◽  
Erin Felton ◽  
Katherine Sear ◽  
Benita Tamrazi ◽  
Joseph Torkildson ◽  
...  

Among childhood cancer survivors, increased stroke risk after cranial radiation therapy may be caused by radiation-induced arteriopathy, but limited data exist to support this hypothesis. Herein, we assess the timing and presence of cerebral arteriopathy identified by magnetic resonance angiography (MRA) after cranial radiation therapy in childhood brain tumor survivors. In a cohort of 115 pediatric brain tumor survivors, we performed chart abstraction and prospective annual follow-up to assess the presence of large vessel cerebral arteriopathy by MRA. We identified 10 patients with cerebral arteriopathy. The cumulative incidence of arteriopathy 5 years post–cranial radiation therapy was 5.4% (CI 0.6%-10%) and 10 years was 16% (CI 4.6%-26%). One patient had an arterial ischemic stroke 2.4 years post–cranial radiation therapy in the distribution of a radiation-induced stenotic artery. We conclude that large vessel arteriopathies can occur within a few years of cranial radiation therapy and can become apparent on MRA in under a year.


Author(s):  
Sinchai Tsao ◽  
Niharika Gajawelli ◽  
Arthur Olch ◽  
Kenneth Wong ◽  
Nicholas Chapman ◽  
...  

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