scholarly journals When Worlds Collide: An Interesting Case of Rhinocerebral Mucormycosis Exacerbated by COVID-19 and Diabetic Ketoacidosis Complicated by Intraorbital Hematoma

Cureus ◽  
2022 ◽  
Author(s):  
Andrew J Ortega ◽  
Sara Alhariri ◽  
M Ammar Kalas ◽  
Jeff Taclob ◽  
Angelica Padilla ◽  
...  
Keyword(s):  
Diabetic Ketoacidosis ◽  
Interesting Case ◽  
Rhinocerebral Mucormycosis ◽  
Intraorbital Hematoma

scholarly journals Rhinocerebral mucormycosis secondary to severe acute pancreatitis and diabetic ketoacidosis: a case report

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jinjing Wang ◽  
Yao Li ◽  
Shuai Luo ◽  
Hong Zheng
Keyword(s):  
Acute Pancreatitis ◽  
Diabetic Ketoacidosis ◽  
Severe Acute Pancreatitis ◽  
Clinical Findings ◽  
Severe Form ◽  
Optimal Treatment ◽  
Diabetic Patients ◽  
Rhinocerebral Mucormycosis ◽  
Patient Prognosis ◽  
Treatment Window

Abstract Introduction Rhinocerebral mucormycosis is a rare and severe form of opportunistic fungal infection that can develop rapidly and cause significant mortality, particularly among diabetic patients suffering from ketoacidosis. Diagnosing rhinocerebral mucormycosis during the early stages of infection is challenging. Case presentation We describe a case of rhinocerebral mucormycosis secondary to severe acute pancreatitis in a patient suffering from diabetic ketoacidosis. In this case, the condition was not diagnosed during the optimal treatment window. we therefore provide a thorough overview of related clinical findings and histopathological characteristics, and we discuss potential differential diagnoses. Conclusions In summary, we described a case of rhinocerebral mucormycosis secondary to severe acute pancreatitis in a patient suffering from diabetic ketoacidosis, with the optimal treatment window for this condition having been missed. This report suggests that a definitive mucormycosis diagnosis can be made based upon tissue biopsy that reveals the presence of characteristic hyphae. Early diagnosis and treatment are essential in order to improve patient prognosis.

scholarly journals Euglycemic Diabetic Ketoacidosis in a Patient with Cocaine Intoxication

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Asma Abu-Abed Abdin ◽  
Muhammad Hamza ◽  
Muhammad S. Khan ◽  
Awab Ahmed
Keyword(s):  
Metabolic Acidosis ◽  
Blood Glucose ◽  
Diabetic Ketoacidosis ◽  
Cocaine Abuse ◽  
Interesting Case ◽  
Anion Gap ◽  
Normal Blood ◽  
Diabetic Patients ◽  
Normal Blood Glucose ◽  
Insulin Dependent Diabetic

Diabetic ketoacidosis (DKA) is characterized by elevated anion gap metabolic acidosis, hyperglycemia, and elevated ketones in urine and blood. Hyperglycemia is a key component of DKA; however, a subset of DKA patients can present with near-normal blood glucose, an entity described as “euglycemic DKA.” This rare phenomenon is thought to be due to starvation and food restriction in insulin dependent diabetic patients. Cocaine abuse is considered a trigger for development of DKA. Cocaine also has anorexic effects. We describe an interesting case of euglycemic DKA in a middle-aged diabetic female presenting with elevated anion gap metabolic acidosis, with near-normal blood glucose, in the settings of noncompliance to insulin and cocaine abuse. We have postulated that cocaine abuse was implicated in the pathophysiology of euglycemic DKA in this case. This case highlights complex physiological interplay between type-1 diabetes, noncompliance to insulin, and cocaine abuse leading to DKA, with starvation physiology causing development of euglycemic DKA.

scholarly journals Rhinocerebral Mucormycosis Secondary to Severe Acute Pancreatitis and Diabetic Ketoacidosis: A Case Report

2021 ◽  
Author(s):  
Jinjing Wang ◽  
Yao Li ◽  
Shuai Luo ◽  
Hong Zheng
Keyword(s):  
Acute Pancreatitis ◽  
Diabetic Ketoacidosis ◽  
Severe Acute Pancreatitis ◽  
Clinical Findings ◽  
Severe Form ◽  
Optimal Treatment ◽  
Diabetic Patients ◽  
Rhinocerebral Mucormycosis ◽  
Patient Prognosis ◽  
Treatment Window

Abstract Introduction: Rhinocerebral mucormycosis is a rare and severe form of opportunistic fungal infection that can develop rapidly and cause significant mortality, particularly among diabetic patients suffering from ketoacidosis. Diagnosing rhinocerebral mucormycosis during the early stages of infection is challenging. Case presentation：We describe a case of rhinocerebral mucormycosis secondary to severe acute pancreatitis in a patient suffering from diabetic ketoacidosis. In this case, the condition was not diagnosed during the optimal treatment window. we therefore provide a thorough overview of related clinical findings and histopathological characteristics, and we discuss potential differential diagnoses.Conclusions: In summary, we described a case of rhinocerebral mucormycosis secondary to severe acute pancreatitis in a patient suffering from diabetic ketoacidosis, with the optimal treatment window for this condition having been missed. This report suggests that a definitive mucormycosis diagnosis can be made based upon tissue biopsy that reveals the presence of characteristic hyphae. Early diagnosis and treatment are essential in order to improve patient prognosis.

scholarly journals Rhinocerebral Mucormycosis in a Patient with AIDS: A Complication of Diabetic Ketoacidosis Following Pentamidine Therapy

1996 ◽  
Vol 23 (4) ◽  
pp. 845-846 ◽  
Author(s):  
V. Abril ◽  
E. Ortega ◽  
P. Segarra ◽  
F. Pedro ◽  
V. Sabater ◽  
...  
Keyword(s):  
Diabetic Ketoacidosis ◽  
Rhinocerebral Mucormycosis

Demodex mite infestation of unknown significance in a patient with rhinocerebral mucormycosis due to Apophysomyces elegans species complex

2013 ◽  
Vol 62 (6) ◽  
pp. 926-928 ◽  
Author(s):  
Vinaykumar Hallur ◽  
Gagandeep Singh ◽  
Shivaprakash M. Rudramurthy ◽  
Rakesh Kapoor ◽  
Arunaloke Chakrabarti
Keyword(s):  
Microscopic Examination ◽  
Species Complex ◽  
Interesting Case ◽  
Rhinocerebral Mucormycosis ◽  
Demodex Mite ◽  
The Past ◽  
Demodex Folliculorum ◽  
Direct Microscopic Examination ◽  
Unknown Significance ◽  
Immunosuppressed Patients

Demodex mites have been reported in the past as a cause of facial rash in immunosuppressed patients. Here, we report an interesting case of possible demodicosis associated with rhinocerebral mucormycosis. The association of mites with a fungus was detected on direct microscopic examination of the scrapings of a nasal ulcer. The mite and the fungus were identified as Demodex folliculorum and Apophysomyces elegans species complex, respectively.

The influence of ketoacids on plasma creatinine assays in diabetic ketoacidosis

2000 ◽  
Vol 248 (6) ◽  
pp. 511-517 ◽  
Author(s):  
F. A. W. Kemperman ◽  
J. A. Weber ◽  
J. Gorgels ◽  
A. P. Van Zanten ◽  
R. T. Krediet ◽  
...  
Keyword(s):  
Diabetic Ketoacidosis ◽  
Plasma Creatinine
Sign in / Sign up

Export Citation Format

Share Document