scholarly journals Case Series of Neonatal Extravasation Injury: Importance of Early Identification and Management

Cureus ◽  
2022 ◽  
Author(s):  
Chun Kai Yew ◽  
Siti Fatimah Noor Mat Johar ◽  
Wee Yi Lim
Keyword(s):  
Early Identification ◽  
Case Series

Early Identification of Severe COVID-19 in Hospitalised Patients: A Large, French Multicentre Case Series

2020 ◽  
Author(s):  
Orianne Weizman ◽  
Antonin Trimaille ◽  
Thibaut Pommier ◽  
Joffrey Cellier ◽  
Laura Geneste ◽  
...  
Keyword(s):  
Early Identification ◽  
Case Series ◽  
Hospitalised Patients

scholarly journals Ischemic Stroke in COVID-19: An Urgent Need for Early Identification and Management

2020 ◽  
Author(s):  
Dinesh V. Jillella ◽  
Nicholas J. Janocko ◽  
Fadi Nahab ◽  
Karima Benameur ◽  
James G. Greene ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Early Identification ◽  
Case Series ◽  
Reperfusion Therapy ◽  
Stroke Risk Factors ◽  
Global Pandemic ◽  
Potential Association ◽  
Co Morbidity ◽  
The Mean ◽  
Mean Time

AbstractObjectiveIn the setting of the Coronavirus Disease 2019 (COVID-19) global pandemic caused by SARS-CoV-2, a potential association of this disease with stroke has been suggested. We aimed to describe the characteristics of patients who were admitted with COVID-19 and had an acute ischemic stroke (AIS).MethodsThis is a case series of PCR-confirmed COVID-19 patients with ischemic stroke admitted to an academic health system in metropolitan Atlanta (USA) between March 24th,2020, and May 5th, 2020. Demographic, clinical, and radiographic characteristics were described.ResultsOf 124 ischemic stroke patients admitted during this study period, 8 (6.5%) were also diagnosed with COVID-19. The mean age of patients was 64.3 ± 6.5 years, 5 (62.5%) male, mean time from last-normal was 4.8 days [SD 4.8], and none received acute reperfusion therapy. All 8 patients had at least one stroke-associated co-morbidity. The predominant pattern of ischemic stroke was embolic; 3 were explained by atrial fibrillation while 5 (62.5%) were cryptogenic. In contrast, cryptogenic strokes were seen in 20 (16.1%) of 124 total stroke admissions during this time.ConclusionsIn our case series, ischemic stroke affected COVID-19 patients with traditional stroke risk factors with an age of stroke presentation typically seen in non-COVID populations. We observed a predominantly embolic pattern of stroke with a higher than expected rate of cryptogenic strokes and with a prolonged median time to presentation and symptom recognition limiting the use of acute reperfusion treatments. These results highlight the need for increased community awareness, early identification, and management of AIS in COVID-19 patients.

#26: Rhino-Orbital Mucormycosis in Immunocompromised Children: Treatment Outcomes of Three Cases

2021 ◽  
Vol 10 (Supplement_1) ◽  
pp. S23-S23
Author(s):  
G Valdés ◽  
M Martínez ◽  
A Morayta
Keyword(s):  
Risk Factors ◽  
Acute Lymphoblastic Leukemia ◽  
Fungal Infection ◽  
Amphotericin B ◽  
Antifungal Therapy ◽  
Early Identification ◽  
Liposomal Amphotericin ◽  
Lymphoblastic Leukemia ◽  
Case Series ◽  
Liposomal Amphotericin B

Abstract Background Mucormycosis is an aggressive opportunistic fungal infection of the family Mucoraceae, including the genera Mucor, Absidia, and Rhizopus. It is the third most common cause of invasive fungal infection, with low incidence, but high mortality (50–90%), and it usually presents in immunocompromised hosts. The fungus spores are ubiquitous in nature and are found in soil, air, and on decaying vegetation. Individuals get infected following inhalation of spores, ingestion, or contamination of wounds. Rhino-orbito-cerebral mucormycosis is the most common form of illness in children. An early diagnosis and a multidisciplinary approach to treatment are necessary to prevent mortality. Methods We present a case series of three immunocompromised children with rhino-orbital mucormycosis in Nacional Medical Center “20 de Noviembre” from 2015 to 2019. We describe time to diagnosis, start of antifungal therapy, surgery involvement, and patient outcomes. Results Patient 1 was a 9-year-old girl with aplastic anemia who developed right palpebral swelling (day 1 of initial symptoms) and was initially diagnosed with preseptal cellulitis. On day 5, a necrotic area appeared in the right inner canthus. Paranasal sinus CT scan showed opacified ethmoidal sinus. Liposomal amphotericin B therapy was started. At day 7, surgical debridement was performed. At day 18, the patient died and the culture of the debrided tissue showed Mucor ramosissimus. Patient 2 was a 15-year-old boy with acute lymphoblastic leukemia who developed a necrotic area in right side of the nose and palate (day 1). Liposomal amphotericin B therapy was initiated. At day 3 and 6, surgery was performed. At day 8, cultures resulted in Rhizopus oryzae, and treatment with caspofungin was added. He had progression of the infection, requiring multiple interventions. Antifungal therapy consisted of 75 days with amphotericin B and 67 days with caspofungin, with resolution. At day 152, he had a event of neutropenia and fever and died of septic shock Patient 3 was a 16-year-old girl with acute lymphoblastic leukemia who developed a necrotic lesion on the palate and right side of the nose (day 1). Direct examination of the lesion showed hyaline, non-septated hyphae. Amphotericin B therapy was initiated and surgery was performed at day 3. By day 7, there was good clinical evolution and resolution the infection. She died at day 12 because of intestinal bleeding and hypovolemic shock. Conclusions The diagnosis and treatment of mucormycosis remains a challenge. Clinical suspicion should be high in patients with risk factors, and early identification and prompt treatment with antifungals and surgical debridement can reduce mortality and improve the prognosis. The poor outcomes of the patients in this case series were mainly due to complications of the underlying disease and not because of mucormycosis. However, in the first case, delayed diagnosis and treatment might have contributed to the unfavorable outcome. The treatment of choice is liposomal amphotericin B. In case 2, a second antifungal therapy included caspofungin due to isolation of R. oryzae, sensitive to echinocandins. Posaconazole can be considered as an alternative option, but it is not available at our institution. Early identification of clinical manifestations and early multidisciplinary treatment with surgical services and antifungal are needed to eliminate the infection. Risk factors must be modified to increase patient survival.

Case series of dementia with Lewy bodies: consensus criteria in practice

2019 ◽  
Vol 28 (1) ◽  
pp. 80-83
Author(s):  
Richard Goodwin
Keyword(s):  
Mental Health ◽  
Neurodegenerative Disorders ◽  
Early Identification ◽  
Dementia With Lewy Bodies ◽  
Case Series ◽  
Lewy Bodies ◽  
Assessment Tools ◽  
Newly Diagnosed ◽  
Psychiatric Illnesses

Objectives: This case series considers three patients newly diagnosed with dementia with Lewy bodies (DLB) whilst under the care of mental health services. The cases demonstrate that the difficulties in diagnosing DLB as early symptoms may resemble other neurodegenerative disorders or psychiatric illnesses. Conclusion: The role of consensus criteria in diagnosis is explored. The use of screening and assessment tools in early identification of DLB is also considered.

A Clinical Study of Twenty-seven Children Exhibiting Functional Hearing Loss

1981 ◽  
Vol 12 (1) ◽  
pp. 26-35 ◽  
Author(s):  
Donald L. McCanna ◽  
Giacinto DeLapa
Keyword(s):  
Hearing Loss ◽  
Clinical Study ◽  
Early Identification ◽  
Behavioral Responses ◽  
Upper Elementary ◽  
Elementary Grades ◽  
Ability Level ◽  
Hearing Problem

This report reviews 27 cases of children exhibiting functional hearing loss. The study reveals that most students were in the upper elementary grades and were predominantly females. These subjects were functioning below their ability level in school and were usually in conflict with school, home, or peers. Tests used were selected on the basis of their helping to provide early identification. The subjects' oral and behavioral responses are presented, as well as ways of resolving the hearing problem. Some helpful counseling techniques are also presented.

The Need for Aggressive Pursuit of Healthy Childhood Voices

1989 ◽  
Vol 20 (1) ◽  
pp. 102-107 ◽  
Author(s):  
Joel C. Kahane ◽  
Robert Mayo
Keyword(s):  
Early Identification ◽  
Voice Disorders ◽  
Prevention Programs ◽  
Incidence Trends ◽  
Aggressive Management ◽  
Prevention And Treatment ◽  
Current Incidence

In this paper we argue for the aggressive management of voice disorders. Aggressive management includes early identification, prevention, and treatment of voice disorders. The argument for aggressive management is supported by current incidence trends, laryngologists' expectations, and the benefits of prevention programs.

From the President: The Power of Early Identification

ASHA Leader ◽  
2014 ◽  
Vol 19 (2) ◽  
pp. 8-9
Author(s):  
Elizabeth McCrea
Keyword(s):  
Early Identification
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