scholarly journals Lymphangioma: A Rare Benign Cystic Pancreatic Lesion

Cureus ◽  
2022 ◽  
Author(s):  
Salman M Alrasheed ◽  
Maha F Alluqmani ◽  
Sabha H Almoallem ◽  
Anmar Y Alshibely ◽  
Hattan E Alharthi ◽  
...  
Keyword(s):  
Pancreatic Lesion

Cystic Pancreatic Lesion Discovered in the Setting of Abdominal Trauma: a Diagnostic Challenge

2016 ◽  
Vol 25 (3) ◽  
pp. 272
Author(s):  
Cosmin Caraiani ◽  
Marcel Tantau ◽  
Magda Rotaru ◽  
Anamaria Pop ◽  
Ioana Rusu ◽  
...  
Keyword(s):  
Abdominal Trauma ◽  
Diagnostic Challenge ◽  
Pancreatic Lesion

.

A retroperitoneal bronchogenic cyst mimicking a pancreatic lesion: a rare mass found in the retroperitoneal region

Chirurgia ◽  
2019 ◽  
Vol 32 (3) ◽  
Author(s):  
Fabrizio Cremona ◽  
Antonio Sciuto ◽  
Dario P. Cassano ◽  
Paola Parente ◽  
Felice Pirozzi
Keyword(s):  
Bronchogenic Cyst ◽  
Pancreatic Lesion ◽  
Retroperitoneal Bronchogenic Cyst

scholarly journals Ferumoxytol-enhanced MR imaging for differentiating intrapancreatic splenules from other tumors

2020 ◽  
Author(s):  
M. R. Muehler ◽  
V. R. Rendell ◽  
L. L. Bergmann ◽  
E. R. Winslow ◽  
S. B. Reeder
Keyword(s):  
Superparamagnetic Iron Oxide ◽  
Pancreatic Neuroendocrine Tumor ◽  
Symptomatic Patient ◽  
Splenic Tissue ◽  
Pancreatic Lesion ◽  
Delayed Imaging ◽  
Post Contrast ◽  
Computed Tomographic ◽  
Institutional Experience ◽  
Slow Intravenous Infusion

Abstract Objectives Ferumoxytol is an ultra-small superparamagnetic iron oxide (USPIO) agent that is taken up by splenic tissue. This study describes our initial institutional experience of ferumoxytol-enhanced MRI (feMRI) for differentiating intrapancreatic splenules (IPS) from other pancreatic lesions. Methods In this retrospective study, patients with computed tomographic imaging that identified small enhancing lesions in the tail of the pancreas subsequently underwent feMRI for further characterization. The feMRI protocol included T2-weighted (T2w) imaging with and without fat suppression (FS), R2* mapping, diffusion-weighted imaging (DWI), and T1-weighted (T1w) imaging with FS, prior to contrast injection. Immediately after slow intravenous infusion with 3 mg/kg body weight ferumoxytol, T1w was repeated. Delayed imaging with all sequences were obtained 24–72 h after ferumoxytol administration. Results Seven patients underwent feMRI. In two patients, the pancreatic lesions were presumed as pancreatic neuroendocrine tumor (PNET) from feMRI and in the remaining 5 IPS. One of the two patients with PNET was symptomatic for NET. In another symptomatic patient with pathologically proven duodenal NET and suspected PNET, the pancreatic lesion was proven to be an IPS on feMRI. IPS demonstrated strong negative enhancement in feMRI on T2w and increased R2* values consistent with splenic tissue, while the presumed PNETs did not enhance. T2w FS was helpful on the pre-contrast images to identify IPS, while R2* did on post-contrast images. Neither DWI nor T1w contributed to differentiating PNETs from IPS. Conclusions This study demonstrates the potential utility of feMRI as a helpful adjunct diagnostic tool for differentiating IPS from other pancreatic lesions. Further studies in larger patient cohorts are needed.

scholarly journals Thermal Liquid Biopsy (TLB) Focused on Benign and Premalignant Pancreatic Cyst Diagnosis

2020 ◽  
Vol 11 (1) ◽  
pp. 25
Author(s):  
Sonia Hermoso-Durán ◽  
Guillermo García-Rayado ◽  
Laura Ceballos-Laita ◽  
Carlos Sostres ◽  
Sonia Vega ◽  
...  
Keyword(s):  
Liquid Biopsy ◽  
Pancreatic Cyst ◽  
Point Of View ◽  
Invasive Technique ◽  
Background Current ◽  
Interesting Point ◽  
Pancreatic Lesion ◽  
Non Invasive ◽  
Patient Diagnosis ◽  
New Biomarkers

Background: Current efforts in the identification of new biomarkers are directed towards an accurate differentiation between benign and premalignant cysts. Thermal Liquid Biopsy (TLB) has been previously applied to inflammatory and tumor diseases and could offer an interesting point of view in this type of pathology. Methods: In this work, twenty patients (12 males and 8 females, average ages 62) diagnosed with a pancreatic cyst benign (10) and premalignant (10) cyst lesions were recruited, and biological samples were obtained during the endoscopic ultrasonography procedure. Results: Proteomic content of cyst liquid samples was studied and several common proteins in the different groups were identified. TLB cyst liquid profiles reflected protein content. Also, TLB serum score was able to discriminate between healthy and cysts patients (71% sensitivity and 98% specificity) and between benign and premalignant cysts (75% sensitivity and 67% specificity). Conclusions: TLB analysis of plasmatic serum sample, a quick, simple and non-invasive technique that can be easily implemented, reports valuable information on the observed pancreatic lesion. These preliminary results set the basis for a larger study to refine TLB serum score and move closer to the clinical application of TLB providing useful information to the gastroenterologist during patient diagnosis.

scholarly journals Egy különleges pancreaselváltozás: kevert differenciációjú nodularitás és diffúz szigetsejtes hyperplasia

2021 ◽  
Vol 162 (6) ◽  
pp. 227-232
Author(s):  
Attila Zalatnai ◽  
Judit Tőke ◽  
Gergely Huszty ◽  
Katalin Müllner ◽  
Miklós Tóth
Keyword(s):  
Progenitor Cells ◽  
Pancreatic Lesion ◽  
First Report ◽  
Pancreatic Differentiation ◽  
Trilineage Differentiation ◽  
Endocrine Symptoms

Összefoglaló. A szerzők egy különleges pancreaselváltozás esetét ismertetik, melyben az acinusok neuroendokrin jellegű transzformációja diffúz, atípusos megjelenésű szigetsejtes hyperplasiával társult, valamint a pancreas mindhárom sejtvonalát (acinaris, ductalis, insularis) tartalmazó nodulusok képződtek. A komplex megjelenés ellenére a kórfolyamat nem járt endokrin tünetekkel. Esetünkben a kiváltó ok hátterében a struktúrák kóros progenitorsejt-differenciációja állhatott. Az irodalomban ilyen közlés eddig nem ismert. Orv Hetil. 2021; 162(6): 227–232. Summary. The authors present a case of a peculiar pancreatic lesion, in which the neuroendocrine transformation of the acini was associated with a diffuse, atypical insular hyperplasia, and micronodules exhibiting trilineage differentiation. Despite the complex alteration, no endocrine symptoms were noted. The case may represent the result of an abnormal pancreatic differentiation raising the possibility of reprogramming of the progenitor cells. To the best of our knowledge, this is the first report of such a lesion in the literature. Orv Hetil. 2021; 162(6): 227–232.

Sign in / Sign up

Export Citation Format

Share Document