scholarly journals Investigation of the Relationship Between Hip and Knee Osteoarthritis and Disordered Spinal and Pelvic Morphology

Cureus ◽  
2022 ◽  
Author(s):  
Vasileios A Kechagias ◽  
Theodoros B Grivas ◽  
Panayiotis J Papagelopoulos ◽  
Vasileios A Kontogeorgakos ◽  
Konstantinos Vlasis
Keyword(s):  
Knee Osteoarthritis ◽  
Pelvic Morphology ◽  
The Relationship

The Relationship Between Changes in Movement and Activity Limitation or Pain in People With Knee Osteoarthritis: A Systematic Review

2021 ◽  
Vol 51 (10) ◽  
pp. 492-502
Author(s):  
Jay-Shian Tan ◽  
Edward Tikoft ◽  
Peter O'Sullivan ◽  
Anne Smith ◽  
Amity Campbell ◽  
...  
Keyword(s):  
Systematic Review ◽  
Knee Osteoarthritis ◽  
Activity Limitation ◽  
The Relationship

Higher dynamic medial knee load predicts greater cartilage loss over 12 months in medial knee osteoarthritis

2011 ◽  
Vol 70 (10) ◽  
pp. 1770-1774 ◽  
Author(s):  
Kim L Bennell ◽  
Kelly-Ann Bowles ◽  
Yuanyuan Wang ◽  
Flavia Cicuttini ◽  
Miranda Davies-Tuck ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Disease Progression ◽  
Cartilage Volume ◽  
Cartilage Defects ◽  
Medial Knee ◽  
Tibial Cartilage ◽  
Medial Knee Osteoarthritis ◽  
Structural Progression ◽  
The Relationship ◽  
Knee Load

ObjectiveMechanical factors, in particular increased medial knee joint load, are believed to be important in the structural progression of knee osteoarthritis. This study evaluated the relationship of medial knee load during walking to indices of structural disease progression, measured on MRI, in people with medial knee osteoarthritis.MethodsA longitudinal cohort design utilising a subset of participants (n=144, 72%) enrolled in a randomised controlled trial of lateral wedge insoles was employed. Medial knee load parameters including the peak knee adduction moment (KAM) and the KAM impulse were measured at baseline using three-dimensional gait analysis during walking. MRI at baseline and at 12 months was used to assess structural indices. Multiple regression with adjustment for covariates assessed the relationship between medial knee load parameters and the annual change in medial tibial cartilage volume. Binary logistic regression was used for the dichotomous variables of progression of medial tibiofemoral cartilage defects and bone marrow lesions (BML).ResultsA higher KAM impulse, but not peak KAM, at baseline was independently associated with greater loss of medial tibial cartilage volume over 12 months (β=29.9, 95% CI 6.3 to 53.5, p=0.01). No significant relationships were seen between medial knee load parameters and the progression of medial tibiofemoral cartilage defects or BML.ConclusionThis study suggests knee loading, in particular the KAM impulse, may be a risk factor for loss of medial tibial cartilage volume. As knee load is modifiable, load-modifying treatments may potentially slow disease progression.

scholarly journals Epidemiological study on the relationship among menopausal condition, bone fragility, and knee osteoarthritis

2020 ◽  
Author(s):  
Eiji Sasaki ◽  
Daisuke Chiba ◽  
Seiya Ota ◽  
Yuka Kimura ◽  
Shizuka Sasaki ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Knee Osteoarthritis ◽  
Epidemiological Study ◽  
Odds Ratio ◽  
Weight Bearing ◽  
Predictive Marker ◽  
P Value ◽  
Mineral Density ◽  
High Turnover ◽  
The Relationship

Abstract Background: Knee osteoarthritis (KOA) occurs more often in middle-aged females. While this age-group experiences comorbid osteoporosis with menopause, its influence on KOA has not been clarified. This epidemiological study aimed to investigate the relationship between menopausal conditions, bone mineral density (BMD), and KOA. Methods: A total of 518 female volunteers who participated in the Iwaki cohort study were enrolled and divided into groups (pre- and post-menopause). Antimullerian hormone (AMH) was measured as a predictive marker for menopause in the pre-menopausal subjects. Weight-bearing anterior-posterior knee radiographs were classified by Kellgren-Lawrence grade, and grade ≥ 2 was defined as definitive KOA (DKOA). Early KOA (EKOA) was defined by Luyten’s criteria, and BMD was measured at a distal radius. The relationship between menopausal condition, BMD, and KOA was analyzed by ROC and regression analysis. Results: Fifty-two participants (10.0%) were diagnosed with EKOA and 204 (39.4%) with DKOA. A total of 393 (75.9%) females began menopause, and the prevalence of DKOA was up to 48.1% and >12.0% in pre-menopause females (p < 0.001, Odds ratio: 6.79). From the ROC analysis in pre-menopausal females, cut-off value of AMH for detecting EKOA was 0.08 ng/ml (AUC: 0.712, p5%CI: 0.527 to 0.897, p-value: 0.025, Odds ratio: 8.28). Regression analysis showed that lower AMH was related to EKOA (p=0.035, Odds ratio: 5.55) and DKOA (p=0.032, Odds 1.59), and lower BMD and high turnover bone metabolism were correlated with DKOA. Conclusions: KOA increased after menopause and was correlated with lower BMD. Furthermore, reduction in AMH was a valuable biomarker for the detection of EKOA.

scholarly journals Mindsets Predict Physical Activity and Relate to Chosen Management Strategies in Individuals with Knee Osteoarthritis

2021 ◽  
Author(s):  
Melissa A. Boswell ◽  
Kris M. Evans ◽  
Sean R. Zion ◽  
Danielle Z. Boles ◽  
Jennifer L. Hicks ◽  
...  
Keyword(s):  
Physical Activity ◽  
Knee Osteoarthritis ◽  
Online Survey ◽  
Management Strategies ◽  
The Elderly ◽  
Activity Level ◽  
Activity Levels ◽  
Group A ◽  
Test Retest Reliability ◽  
The Relationship

Objectives. We compared mindsets about physical activity among those with and without knee osteoarthritis and investigated if these mindsets relate to physical activity level and symptom management. Methods. Participants with (n=150) and without (n=152) knee osteoarthritis completed an online survey at study enrollment (T1). Participants with knee osteoarthritis repeated the survey three weeks later (T2; n=62). The mindset questionnaire, scored from 1-4, assessed the extent to which individuals associate the process of exercising with less appeal-focused qualities (e.g., boring, painful, isolating, and depriving) vs. appeal-focused (e.g., fun, pleasurable, social, and indulgent) versus. Using linear regression, we examined the relationship between mindset and having knee osteoarthritis, and, in the subgroup of participants with knee osteoarthritis, the relationship between mindset at T1 and physical activity (via the Physical Activity Scale for the Elderly) at T2. We also compared mindsets between those who use medication for management and those who use exercise. Results. A less appeal-focused mindset regarding physical activity was marginally associated with having knee osteoarthritis (β=-0.125, P=0.096). Within the knee osteoarthritis group, a more appeal-focused mindset predicted higher future physical activity (β=20.68, P=0.039), controlling for current physical activity, demographics, and health. Individuals that used exercise with or without pain medication or injections had more appeal-focused process mindsets than those who used medication or injections without exercise (P<0.001). Further, the process mindset inventory demonstrated strong internal consistency (α=0.92 at T1 for n=150 and α=0.92 at T2 for n=62) and test-retest reliability (ICC>0.841, P<0.001) within the knee osteoarthritis population. Conclusion. In individuals with knee osteoarthritis, mindsets predict future physical activity levels and relate to an individual's management strategy. Mindsets are a reliable and malleable construct and may be a valuable target for increasing physical activity and improving adherence to rehabilitation strategies involving exercise among individuals with knee osteoarthritis.

scholarly journals Life course longitudinal growth and risk of knee osteoarthritis at age 53 years: evidence from the 1946 British birth cohort study

2020 ◽  
Author(s):  
Katherine A Staines ◽  
Rebecca J Hardy ◽  
Hasmik J Samvelyan ◽  
Kate A Ward ◽  
Rachel Cooper
Keyword(s):  
Life Course ◽  
Knee Osteoarthritis ◽  
Growth Curve ◽  
Birth Cohort Study ◽  
Childhood And Adolescence ◽  
Limited Evidence ◽  
Male And Female ◽  
Height Gain ◽  
Health And Development ◽  
The Relationship

Objectives To examine the relationship between height gain across childhood and adolescence with knee osteoarthritis in the MRC National Survey of Health and Development (NSHD). Methods Data are from 3035 male and female participants of the NSHD. Height was measured at ages 2, 4, 6, 7, 11 and 15 years, and self-reported at ages 20 and 26 years. Associations between (i) height at each age (ii) height gain during specific life periods (iii) Super-Imposition by Translation And Rotation (SITAR) growth curve variables of height size, tempo and velocity, and knee osteoarthritis at 53 years were tested. Results In sex-adjusted models, taller height at 4 and 6 years were modestly associated with decreased odds of knee osteoarthritis at age 53 (ORs per 1cm increase in height at age 6: 0.97 and age 4: 0.98 (95% CI: 0.95-1.00)). These associations were attenuated after adjustment for potential confounders. Similarly, taller adult achieved height measured at 26 and 53 years of age were associated with decreased odds of knee osteoarthritis (OR per 1cm increase in height: 0.98 (95% CI 0.96 to 1.00)). No associations were found between height gain during specific life periods or the SITAR growth curve variables and odds of knee osteoarthritis. Conclusions There was some limited evidence to suggest that taller height in childhood is associated with decreased odds of knee osteoarthritis at age 53 years in this cohort. This work enhances our understanding of osteoarthritis predisposition and the contribution of life course height to this.

scholarly journals The relationship between sex, bone and stress hormones and knee osteoarthritis

2020 ◽  
Vol 28 ◽  
pp. S409
Author(s):  
I.A. Szilagyi ◽  
J.H. Waarsing ◽  
M. Kavousi ◽  
J.B. van Meurs ◽  
S.M. Bierma-Zeinstra
Keyword(s):  
Knee Osteoarthritis ◽  
Stress Hormones ◽  
The Relationship

scholarly journals The relationship between pelvic drop during walking and radiographic medial knee osteoarthritis: the most study

2012 ◽  
Vol 20 ◽  
pp. S95-S96
Author(s):  
K. Gross ◽  
J. Niu ◽  
A. Chacko ◽  
Y. Zhang ◽  
D.J. Mattson ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Medial Knee ◽  
Medial Knee Osteoarthritis ◽  
The Relationship
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