scholarly journals A Case of Drug-Induced Interstitial Lung Disease Caused by Epirubicin and Cyclophosphamide Therapy Before Breast Cancer Surgery

Cureus ◽  
2021 ◽  
Author(s):  
Ayaka Egashira ◽  
Toyoshi Yanagihara ◽  
Naruhiko Ogo ◽  
Tatsuma Asoh ◽  
Takashige Maeyama
Keyword(s):  
Breast Cancer ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Cancer Surgery ◽  
Breast Cancer Surgery ◽  
Drug Induced ◽  
Cyclophosphamide Therapy

scholarly journals Drug-Induced Interstitial Lung Disease after Anthracycline-Combined Chemotherapy for Breast Cancer: A Case Report and Literature Review

2021 ◽  
pp. 1671-1676
Author(s):  
Hideko Hoshina ◽  
Hiroyuki Takei
Keyword(s):  
Breast Cancer ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Triple Negative ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
Combined Chemotherapy ◽  
Drug Induced ◽  
Node Biopsy

Drug-induced interstitial lung disease (DILD) has been occasionally reported with various causative drugs. In the context of breast cancer, anthracycline infrequently causes pulmonary adverse events. We report a 67-year-old woman with cT2N0M0 triple-negative breast cancer who received neoadjuvant chemotherapy with anthracycline-combined chemotherapy with pegfilgrastim. She developed fever, cough, and shortness of breath after 21 days of the scheduled fourth cycle of anthracycline. Computed tomography revealed drug-induced interstitial pneumonia. Prednisolone (1 mg/kg) was administrated and gradually decreased. Thereby, interstitial pneumonia quickly improved. Partial resection of the left breast and sentinel lymph node biopsy were performed, and we diagnosed ypT1bN0. The patient received 4 cycles of taxane and hypofractional radiotherapy and survived without any recurrences over the following 37 months. We report a rare case of DILD due to anthracycline-combined chemotherapy. Twenty-five cases of DILD with breast cancer after administration of anthracycline have been reported so far. However, 14 cases occurred during taxane. Most of the cases had remission by steroid treatment. The patients with respiratory symptoms during chemotherapy should be suspicious of not only infection but also DILD.

scholarly journals Prospective Study of Drug-induced Interstitial Lung Disease in Advanced Breast Cancer Patients Receiving Everolimus Plus Exemestane

2019 ◽  
Vol 14 (4) ◽  
pp. 441-451 ◽  
Author(s):  
Annelieke E. C. A. B. Willemsen ◽  
Jolien Tol ◽  
Nielka P. van Erp ◽  
Marianne A. Jonker ◽  
Maaike de Boer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Interstitial Lung Disease ◽  
Prospective Study ◽  
Advanced Breast Cancer ◽  
Lung Disease ◽  
Cancer Patients ◽  
Advanced Breast ◽  
Breast Cancer Patients ◽  
Drug Induced

Diagnostic and Curative Breast-Cancer Surgery: Presurgical Distress and Predictors

2006 ◽  
Author(s):  
Julie B. Schnur ◽  
Guy H. Montgomery ◽  
Michael N. Hallquist ◽  
Alisan B. Goldfarb ◽  
Jeffrey H. Silverstein ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Surgery ◽  
Breast Cancer Surgery
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