scholarly journals Rhabdomyolysis and Neurological Manifestation With Progressive Weakness in a Young Adult: A Rare Extrapulmonary Presentation of Mycoplasma Pneumoniae

Cureus ◽  
2021 ◽  
Author(s):  
Ojbindra KC ◽  
Punya H Dahal ◽  
Manisha Koirala ◽  
Afua D NtemMensah
Keyword(s):  
Young Adult ◽  
Mycoplasma Pneumoniae ◽  
Neurological Manifestation ◽  
Progressive Weakness

OP82 – 2546: Neurological manifestation in children with Mycoplasma pneumoniae infection

2015 ◽  
Vol 19 ◽  
pp. S26
Author(s):  
J. Kammer ◽  
S. Ziesing ◽  
L. Aguirre Davila ◽  
S. Illsinger ◽  
A.M. Das ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Neurological Manifestation ◽  
Mycoplasma Pneumoniae Infection

scholarly journals Effect of 23S rRNA gene mutations in Mycoplasma pneumoniae on severity of community-­acquired pneumonia in young adult patients treated at the Smolensk military hospital

2020 ◽  
Vol 22 (4) ◽  
pp. 306-312
Author(s):  
O.V. Ivanova ◽  
Inna A. Edelstein ◽  
O.I. Romashov ◽  
Roman S. Kozlov
Keyword(s):  
Young Adult ◽  
Mycoplasma Pneumoniae ◽  
Gene Mutations ◽  
Community Acquired Pneumonia ◽  
Adult Patients ◽  
23S Rrna ◽  
Military Hospital ◽  
Rrna Gene ◽  
Resistant Genotype ◽  
23S Rrna Gene

Objective. To evaluate effect of 23S rRNA gene mutations in Mycoplasma pneumoniae on severity of community-acquired pneumonia (CAP) in young adult patients. Materials and Methods. A total of 42 case histories of young adult patients with CAP treated at the Smolensk military hospital over the period of 25 October 2017 to 25 December 2019 were reviewed. «AmpliSens® Mycoplasma pneumoniae/Chlamydophila pneumoniae-FL» real-time PCR kit was used to detect M. pneumoniae from nasopharyngeal swabs collected prior to antimicrobial therapy. Testing for 23S rRNA gene mutations conferring macrolide resistance was performed by real-time PCR melt curve analysis (patent no. 2646123) and confirmed by DNA sequencing. Results. All patients had a clinical picture of non-severe CAP on hospital admission. All patients were treated with standard doses of azithromycin or clarithromycin. No respiratory failure or any other complications were observed. Macrolide-resistant genotype of M. pneumoniae was detected in 4 (9.5%) patients. Clinical, laboratory and radiological resolution of pneumonia in all cases occurred on day 10– 16, regardless of the presence of macrolide-resistant genotype. Conclusions. There were no differences in clinical course of severity between CAP caused by M. pneumoniae with 23S rRNA gene mutation and CAP caused by wild-type M. pneumoniae The presence of mutations in the 23S rRNA gene of M. pneumoniae did not worsen the clinical course of CAP.

scholarly journals Tuberculous pleurisy mimicking Mycoplasma pneumoniae infection in a previously healthy young adult

Medicine ◽  
2018 ◽  
Vol 97 (20) ◽  
pp. e10811
Author(s):  
Daizo Yaguchi ◽  
Motoshi Ichikawa ◽  
Masato Shizu ◽  
Noriko Inoue ◽  
Daisuke Kobayashi ◽  
...  
Keyword(s):  
Young Adult ◽  
Mycoplasma Pneumoniae ◽  
Healthy Young Adult ◽  
Tuberculous Pleurisy ◽  
Mycoplasma Pneumoniae Infection

scholarly journals Encephalomyelopathy associated with HTLV-I: A primary disease or coexisting with multiple sclerosis?

2013 ◽  
Vol 7 (4) ◽  
pp. 439-443 ◽  
Author(s):  
Ana Paula Silva Champs ◽  
Valéria Maria de Azeredo Passos ◽  
Sandhi Maria Barreto ◽  
Paulo Caramelli ◽  
Carla Meirelles de Melo ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Differential Diagnosis ◽  
Neurological Diseases ◽  
Cognitive Disorders ◽  
Signs And Symptoms ◽  
Neurological Manifestation ◽  
Motor Disorders ◽  
Sensory Disturbance ◽  
Brain Involvement ◽  
Progressive Weakness

ABSTRACT HTLV-I-associated myelopathy (HAM/TSP) is the most common neurological manifestation of HTLV-I, causing progressive weakness, sensory disturbance, and sphincter dysfunction. Although motor disorders have been well described, few studies have associated cognitive disorders and HTLV-I infection. In areas endemic for HTLV-I infection, the differential diagnosis between HAM/TSP and other myelopathy etiologies can be difficult, particularly if the patient has signs and symptoms of brain involvement, since seropositive HTLV-I patients can present other neurological diseases. Here, we report one case initially diagnosed as Multiple Sclerosis (MS) which, upon further investigation, was found to be HTLV-I seropositive.

Fine Structure of Interdental Cells in the Mouse Cochlea

1970 ◽  
Vol 28 ◽  
pp. 140-141
Author(s):  
Roberta M. Bruck
Keyword(s):  
Fine Structure ◽  
Electron Microscope ◽  
Young Adult ◽  
Uranyl Acetate ◽  
Ground Substance ◽  
Tectorial Membrane ◽  
Lead Citrate ◽  
Unusual Structure ◽  
Thin Sections ◽  
Collagenous Fibers

An unusual structure in the cochlea is the spiral limbus; this periosteal tissue consists of stellate fibroblasts and collagenous fibers embedded in a translucent ground substance. The collagenous fibers are arranged in vertical columns (the auditory teeth of Haschke). Between the auditory teeth are interdental furrows in which the interdental cells are situated. These epithelial cells supposedly secrete the tectorial membrane.The fine structure of interdental cells in the rat was reported by Iurato (1962). Since the mouse appears to be different, a description of the fine structure of mouse interdental cells' is presented. Young adult C57BL/6J mice were perfused intervascularly with 1% paraformaldehyde/ 1.25% glutaraldehyde in .1M phosphate buffer (pH7.2-7.4). Intact cochlea were decalcified in .1M EDTA by the method of Baird (1967), postosmicated, dehydrated, and embedded in Araldite. Thin sections stained with uranyl acetate and lead citrate were examined in a Phillips EM-200 electron microscope.

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