scholarly journals Obscure Gastrointestinal Bleeding Due to Non-steroidal Anti-inflammatory Drug-Induced Colopathy

Cureus ◽  
2021 ◽  
Author(s):  
Huda A Meshikhes ◽  
Mohammed A Duhaileb ◽  
Ali A Alzahir ◽  
Sami A Almomen ◽  
Abdul-Wahed N Meshikhes
Keyword(s):  
Gastrointestinal Bleeding ◽  
Obscure Gastrointestinal Bleeding ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals Capsule Endoscopy for Obscure Gastrointestinal Bleeding in Patients with Comorbid Rheumatic Diseases

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Neal Shahidi ◽  
George Ou ◽  
Jessica Tong ◽  
Ricky Kwok ◽  
Cherry Galorport ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Rheumatic Diseases ◽  
Capsule Endoscopy ◽  
Vascular Lesions ◽  
Obscure Gastrointestinal Bleeding ◽  
Oral Steroid ◽  
Positive Finding ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Mass Lesions

Background and Aim. We evaluated the association between patients with rheumatic diseases (RD) suffering from obscure gastrointestinal bleeding (OGIB) and positive capsule endoscopy (CE) findings. Methods. All CE procedures performed on patients with RD and OGIB were assessed from a large database at St. Paul’s Hospital (Vancouver, BC, Canada) between December 2001 and April 2011. A positive finding on CE was defined as any pathology, including ulcers/erosions, vascular lesions, and mass lesions, perceived to be the source of bleeding. Results. Of the 1133 CEs performed, 41 (4%) complete CEs were for OGIB in patients with RD. Of these, 54% presented with overt bleeding. Mean age was 66 years. Positive findings were seen in 61% of patients. Ulcerations/erosions (36%) and vascular lesions (36%) were the most common findings. Significant differences between the RD versus non-RD populations included: inpatient status, nonsteroidal anti-inflammatory drug (NSAIDs) use, oral steroid use, and mean Charlson index score (all P≤0.008). Similar nonsignificant trends were seen between positive and negative CEs among the RD population. Conclusions. The correlation between RD and positive CE findings is likely influenced by ongoing anti-inflammatory drug use, poorer health status, and a predisposition for angiodysplastic lesions.

Non Steroidal Anti-Inflammatory Drug Induced Damage on Lower Gastro-Intestinal Tract: Is There an Involvement of Microbiota?

2014 ◽  
Vol 9 (3) ◽  
pp. 196-204 ◽  
Author(s):  
Lucia Montenegro ◽  
Giuseppe Losurdo ◽  
Raffaele Licinio ◽  
Maria Zamparella ◽  
Floriana Giorgio ◽  
...  
Keyword(s):  
Intestinal Tract ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Gastro Intestinal Tract

scholarly journals Back Pain and Radiculopathy from Non-Steroidal Anti-Inflammatory Drug-induced Dorsal Epidural Haematoma

2019 ◽  
Vol 12 (3) ◽  
pp. e229015 ◽  
Author(s):  
Jaime L Martinez Santos ◽  
Mohammed Alshareef ◽  
Stephen P Kalhorn
Keyword(s):  
Back Pain ◽  
Epidural Haematoma ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals Involvement of gliadin, a component of wheat gluten, in increased intestinal permeability leading to non-steroidal anti-inflammatory drug-induced small-intestinal damage

PLoS ONE ◽  
2019 ◽  
Vol 14 (2) ◽  
pp. e0211436 ◽  
Author(s):  
Sunao Shimada ◽  
Tetsuya Tanigawa ◽  
Toshio Watanabe ◽  
Akinobu Nakata ◽  
Naoki Sugimura ◽  
...  
Keyword(s):  
Intestinal Permeability ◽  
Wheat Gluten ◽  
Intestinal Damage ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Small Intestinal ◽  
Anti Inflammatory

Non-Steroidal Anti-Inflammatory Drug-Induced Gastropathy

1989 ◽  
Vol 4 (2) ◽  
pp. 77-94 ◽  
Author(s):  
S. Szabo ◽  
W. F. Spill ◽  
K. D. Rainsford
Keyword(s):  
Drug Induced ◽  
Inflammatory Drug ◽  
Anti Inflammatory
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