scholarly journals Epidemiological Study of the Discoid Meniscus: Investigating Demographic-Based Predictors in Large-Scale Claims Database

Cureus ◽  
2021 ◽  
Author(s):  
Sahej Randhawa ◽  
Emily Tran ◽  
Nicole A Segovia ◽  
Theodore Ganley ◽  
Marc Tompkins ◽  
...  
2021 ◽  
Vol 9 (7_suppl3) ◽  
pp. 2325967121S0008
Author(s):  
Sahej S Randhawa ◽  
Emily P Tran ◽  
Nicole A Segovia ◽  
Theodore J Ganley ◽  
Marc Tompkins ◽  
...  

Background: Discoid meniscus epidemiology remains poorly defined for race and sex, in part, due to limitations of retrospective studies and small case series. A better understanding of epidemiology may improve clinical care and diagnostic precision. Purpose: Our purpose is to better define the epidemiology of discoid meniscus by analyzing a large, national database for incidence rates by sex and race. Methods: Analysis was conducted on the national-scale Clinformatics Data Mart Database by Optum. Proportions of the database’s racial categories (Asian, Black, Hispanic, White, and Unknown) in the total population of diagnosed discoid meniscus cases (n = 1,006) were calculated and compared via chi-squared tests to the total database population (n = 65,759,970). This analysis was repeated for the population of patients who received knee arthroscopies (81,205). Incidence rates were calculated from these populations as well. Finally, a multivariable logistic regression analysis based on the population of arthroscopy-receiving patients was performed to control for age, reported gender, and income. Results: Proportions of Asian, Black, Hispanic, and White racial categories in the discoid meniscus group were 5.7%, 7.3%, 20.6%, 66.4%, respectively; the proportions of each racial category in the total population were 5.2%, 10.3%, 13.5%, 71.0%, respectively. Incidence rates (per 10,000) for these groups in the arthroscopy population were 72.9, 25.6, 49.2, 25.6, respectively. Our logistic regression model indicated that race was not a statistically significant predictor for our dataset after income adjusting. Adjusting for other covariates, the odds of a discoid meniscus diagnosis decreased by 6% for each increase in age (p < 0.001) and were 41% lower for males compared to females (p < 0.001). Conclusion: Prior studies have suggested that race (Asian and Hispanic, is a predictor of higher incidence of discoid meniscus – this study did not show a difference in incidence based upon race. Patient sex and age was identified as significant predictors for discoid meniscus, and increasing age showed a decreasing incidence of this condition. This study’s analysis of a large, national claims database allows for a comprehensive epidemiological study on this topic, offering proportions and incidence rates by race appropriate for application to the US population. Its conclusions promote patient sex and age as significant predictors and question the beliefs on race-associated incidence often based on comparing results from the corpus of single-site cohort studies. Tables/Figures: [Table: see text]


Author(s):  
Pushpendra Singh ◽  
Ravindra Kumar ◽  
Aparup Das

Background: Tuberculosis (TB) elimination program in India relies on detecting symptomatic patients through molecular diagnosis and providing speedy treatment, leaving individuals with no classical symptoms of TB (asymptomatic) behind in the population. Considering the contribution of such asymptomatic individuals to transmission of TB, it is important to timely identify them, especially in high-endemic settings. However, no community-level study has so far been conducted to record the incidences of asymptomatic cases in India. Therefore, this study was planned to know whether Mycobacterium tuberculosis, the causal pathogen of TB is prevalent in individuals presenting no classical symptoms in a highly endemic populations belonging to Saharia tribe, a Particularly Vulnerable Tribal Group (PVTG) in India. Methods: We performed molecular epidemiological study in 15 villages (n= 808) of Pohri block, Shivpuri district, Madhya Pradesh, India following population-wide random sampling of both symptomatic (ns=216) and asymptomatic (na=592) individuals. Though a total of 890 subjects were involved in the study, the sputum samples for the qPCR test could be collected only from 808 subjects. Detection of M. tuberculosis in sputum samples was done using TaqMan chemistry-based qPCR assay. Results: Sixteen (2.7%) individuals were found to be positive of M. tuberculosis among the 592 asymptomatic cases. The prevalence of M. tuberculosis DNA positivity was comparable between symptomatic (2.3%) and asymptomatic (2.7%) individuals. Conclusion: The present findings, though preliminary, pending large-scale screening approaches in other high-endemic populations employing both classical and advanced diagnosis methods, are daunting. Such community-wide screening approaches should therefore be integrated in the program if TB-free India is to be achieved by the year 2025.


2019 ◽  
Vol 54 (7) ◽  
pp. 621-627 ◽  
Author(s):  
Hiroki Sato ◽  
Hiroshi Yokomichi ◽  
Kazuya Takahashi ◽  
Kentaro Tominaga ◽  
Takeshi Mizusawa ◽  
...  

2007 ◽  
Vol 10 (6) ◽  
pp. A430
Author(s):  
C Hankin ◽  
JD Dunn ◽  
R Fenrick ◽  
L Fish ◽  
Z Wang ◽  
...  

2009 ◽  
Vol 28 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Estefanía Rodríguez ◽  
Jose M. García-Garrido ◽  
Pedro A. García ◽  
Mercedes Campos

2017 ◽  
Vol 236 ◽  
pp. 137-143 ◽  
Author(s):  
Pikka Jokelainen ◽  
Maarja Tagel ◽  
Kerli Mõtus ◽  
Arvo Viltrop ◽  
Brian Lassen

Author(s):  
Anil Kumar Dadhich ◽  
Ramgopal Meena

Background: Varicocele, an abnormal dilatation and tortuosity of the pampiniform plexus of veins is found in about 15% of the general population with a marked left sided predominance. However this incidence rises to 35% in men with primary infertility and 70 to 80% in men with secondary infertility. Methods: Hospital based prospective study conducted on 100 cases reporting to General surgery department within the study duration and eligible as per inclusion criteria was included in study. Results: In our study out of Out of 100 patients maximum 42.00% patients were farmer followed by 22.00% patients were Coolies and Rickshaw Pullers, 17.00% patients were students, 10.00% were laborer and 9.00% were policemen. Conclusion: It conclude that Varicocele epidemiology remains incompletely understood. We need well‑designed, large‑scale studies that include evaluation of important clinical factors to comprehend fully the epidemiological aspects of this condition.


2014 ◽  
Vol 34 (5) ◽  
pp. 949-956 ◽  
Author(s):  
Hirotaka Katada ◽  
Naoichiro Yukawa ◽  
Hisashi Urushihara ◽  
Shiro Tanaka ◽  
Tsuneyo Mimori ◽  
...  

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