scholarly journals A Case-Control Study on Chromosomal Anomalies in Parents Experiencing Repeated Spontaneous Abortions From Northern India

Cureus ◽  
2021 ◽  
Author(s):  
Malamoni Dutta ◽  
Putul Mahanta ◽  
Bharati Basumatary ◽  
Ranjumoni Konwar
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Chromosomal Anomalies ◽  
Spontaneous Abortions ◽  
Northern India ◽  
Control Study

Prevalence, Risk Factors, and Short-Term Outcomes of Full-Term Low Birth Weight Infants Born at a Tertiary Academic Center: A Prospective Case–Control Study

2021 ◽  
Author(s):  
Heidi K. Al-Wassia ◽  
Shahd K. Baarimah ◽  
Asmaa H. Mohammedsaleh ◽  
Manal O. Alsulami ◽  
Ragad S. Abbas ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Case Control Study ◽  
Case Control ◽  
Adverse Outcomes ◽  
Chromosomal Anomalies ◽  
Short Term ◽  
Term Infants ◽  
Control Study

Objective Low birth weight (LBW) infants (<2,500 g) continued to be a global health problem because of the associated short- and long-term adverse outcomes. The study aimed to determine the prevalence, risk factors, and short-term outcomes of term LBW infants Study Design A prospective and case–control study. All infants born consecutively from September 1, 2018 to August 31, 2019 were included. Cases, term LBW infants, were 1:1 matched to controls, appropriate for gestational age (AGA) term infants. Major congenital or chromosomal anomalies and multiple pregnancies were excluded. Results The prevalence of term LBW in the studied period was 4.8%. Mothers of term LBW infants had significantly lower body mass index (p = 0.05), gained less weight (p = 0.01), had a history of previous LBW (p = 0.01), and lower monthly income (p = 0.04) compared with mothers of term AGA infants even after adjustment for confounders. A nonsignificant higher number of term LBW infants needed NICU admission, while their need for phototherapy was deemed significant. Conclusion We identified nutritional and socioeconomic maternal factors that are significantly associated with LBW infants and should be targeted during antenatal visits to improve neonatal outcomes. Key Points

Biomass fuel and risk of tuberculosis: a case–control study from Northern India

2010 ◽  
Vol 66 (5) ◽  
pp. 457-461 ◽  
Author(s):  
P V M Lakshmi ◽  
Navkiran Kaur Virdi ◽  
J S Thakur ◽  
Kirk R Smith ◽  
Michael N Bates ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Biomass Fuel ◽  
Northern India ◽  
Control Study

Assessment of Reporting Consistency in a Case-Control Study of Spontaneous Abortions

1991 ◽  
Vol 133 (5) ◽  
pp. 477-488 ◽  
Author(s):  
Laura Fenster ◽  
Shanna H. Swan ◽  
Gayle C. Windham ◽  
Raymond R. Neutra
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Spontaneous Abortions ◽  
Control Study

LUPUS ANTICOAGULANT AND REPEATED ABORTIONS: A CASE- CONTROL STUDY

1987 ◽  
Author(s):  
T Barbui ◽  
S Cortelazzo ◽  
M Galli ◽  
F Parazzini ◽  
E Radici ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Lupus Anticoagulant ◽  
Case Control Study ◽  
Working Party ◽  
Sociodemographic Factors ◽  
Case Control ◽  
Spontaneous Abortions ◽  
Tenfold Increase ◽  
Clinical Series ◽  
Control Study

In the last few years a role of Lupus Anticoagulant (LAC) in the aetiology of repeated spontaneous abortions and intrauterine deaths has been repeatedly suggested. To quantify this association few da ta are available, since the published reports are generally based on uncontrolled and small clinical series. We have analyzed data from a case-control study conducted in Bergamo and Milan, two contiguous provinces in Lombardia, Italy. Cases were 63 women, mean age 30 years, range 23-40, with 2 or more "sine causa" spontaneous abortions (repeated abortions) admitted between March 1985 and December 1986 to the Ospedali Riuniti of Bergamo and Istituti Clinici di Perfezionamento of Milan. Controls were 63 women, mean age 32 years, range 20-49, with 1 or more live births and without spon taneous abortions, admitted to the same Institutions for neither gynaecological nor cardiovascular acute conditions. Informations were collected on sociodemographic factors, gynaecological and obstetrical data and related medical history. LAC was diagnosed according to the Working Party reccomandations (1983) and Systemic Lupus Erythematosus (SLE) according to the revised criteria of ihe American Rheumatism Association (1982). 11 out of 63 cases (17%) (95% confidence interval ranging from 9.5% to 34% based on the Poisson's approximation) were LAC positive, whereas in none of 63 controls this inhibitor was detected (X2 1adjusted for age = 10.1, p= 0.02). Similarly SLE was diagnosed in 4 cases (all having a Lupus Anticoagulant) and in none control (x2 1adjusted for age= 4.17, p=0.02). These findings confirm that LAC is associated with a positive history of repeated abortions, being present in about 10% of the cases. Conclusive estimate of relative risk is prevented by the small control gr'oup size (i.e. lack of positivity for LAC in controls), but very elevated risk (many tenfold increase) is sugge. sted.

Role of Functional Polymorphisms of P53 and P73 Genes with the Risk of Prostate Cancer in a Case-Control Study from Northern India

2011 ◽  
Vol 42 (2) ◽  
pp. 122-127 ◽  
Author(s):  
Rama Devi Mittal ◽  
Ginu P. George ◽  
Jyotsna Mishra ◽  
Tulika Mittal ◽  
Rakesh Kapoor
Keyword(s):  
Prostate Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Functional Polymorphisms ◽  
Northern India ◽  
Control Study

scholarly journals Detection of human herpes viruses 1-5 in miscarriage: A case-control study

2020 ◽  
Author(s):  
Javad Charostad ◽  
Talat Mokhtari-Azad ◽  
Jila Yavarian ◽  
Nastaran Ghavami ◽  
Seyed Mahmood Seyed Khorrami ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Spontaneous Abortions ◽  
Herpes Viruses ◽  
Human Herpes ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Intrauterine Infections ◽  
Control Study ◽  
Human Herpes Viruses

Background: Miscarriage is the spontaneous pregnancy loss before 24 wk of gestation. The incidence rate of miscarriage over the past few decades has shown steady or even growing trends. Viral intrauterine infections are one of the probable etiological causes of miscarriage. Previous evidence have shown that human herpes viruses (HHVs) could be considered as the potential reasons for intrauterine infections and adverse pregnancy outcomes. Objective: This case-control study aimed to detect HHV1-5 DNAs in placental tissues and assess their association with miscarriage during the first 24 wk of pregnancy in spontaneous and therapeutic abortions. Materials and Methods: Placental tissues from 83 women with spontaneous abortions during the first and the second trimesters of pregnancy and 81 women with therapeutic abortion during the same gestational age were collected. The DNA extraction was performed by the phenol/chloroform method. A part of the DNA polymerase gene of HHVs was amplified with multiplex nested-polymerase chain reaction. The polymerase chain reaction products were subjected to sequencing. Results: The results showed the presence of human cytomegalovirus genome in the placenta of both spontaneous (8.4%) and therapeutic (4.9%) abortions. No statistically significant differences were found between these two groups. The other investigated viruses were not detected here. Conclusion: In conclusion, like some other studies, no correlation was detected between the HHVs placental infections and the increased risk of spontaneous abortions. In order to find the actual role of HHVs infections in miscarriage, further investigations should be performed on a larger sample size in different areas. Key words: Spontaneous abortion, Therapeutic abortion, Infections, Human herpes viruses.

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